scholarly journals Effect of Sodium Valproate on Cardiac Function in Epileptic Children by Tissue Doppler Echocardiography

2020 ◽  
Author(s):  
Ali Kamani ◽  
Hadis Omidi ◽  
Fatemeh Dorreh ◽  
Fakhredin Shariatmadari ◽  
Yazdan Ghandi
Keyword(s):  
Ventricular Function ◽  
Cardiac Dysfunction ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Control Group ◽  
Oxidative Balance ◽  
Increased Risk ◽  
Epileptic Children ◽  
Pulsed Wave Doppler

The antiepileptic Valproic acid (VPA) changes the oxidative/ anti-oxidative balance that results in oxidative stress and maybe an increased risk of cardiac dysfunction. The aim of this study was to investigate the effect of VPA on ventricular function in epileptic children. We designed a study to evaluate ventricular function in epileptic children who had received VPA for at least one year. All subjects were evaluated using standard echocardiography, pulsed wave Doppler (PWD), and tissue Doppler imaging (TDI). This study consisted of 60 patients with epilepsy (mean age 10.30±3.21 years) and 60 healthy subjects in the control group (mean age 10.28±3.18 years). The duration of antiepilepsy medication ranged from 1.4 to 10 years, and the dose of VPA was 5-30 mg/kg. The ejection fraction and fractional shortening (P=0.841 and 0.064, respectively) were not significantly different between the two groups. The present study reports subclinical right and left ventricular systolic and diastolic dysfunction along with longitudinal ventricular motion disorder. It is recommended the evaluation of subclinical cardiac dysfunction in children treated by VPA.

Assessment of Left Ventricular Function and Tei Index by Tissue Doppler Imaging in Patients with Slow Coronary Flow

2009 ◽  
Vol 26 (10) ◽  
pp. 1167-1172 ◽  
Author(s):  
Merih Baykan ◽  
Emre Cumhur Baykan ◽  
Salih Turan ◽  
Ömer Gedikli ◽  
Şahin Kaplan ◽  
...  
Keyword(s):  
Left Ventricular Function ◽  
Ventricular Function ◽  
Tissue Doppler Imaging ◽  
Coronary Flow ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Tei Index ◽  
Slow Coronary Flow

scholarly journals Assessment of left ventricular systolic and diastolic functions in severely malnourished children

2019 ◽  
Vol 67 (1) ◽  
Author(s):  
Gihan M. Bebars ◽  
Hany T. Askalany
Keyword(s):  
Diastolic Dysfunction ◽  
Diastolic Function ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Control Group ◽  
Nutritional Rehabilitation ◽  
Malnourished Children ◽  
Grade Ii ◽  
Diastolic Functions

Abstract Background Malnourished children endure many changes in body composition and lose heart and skeletal muscle mass. Diastolic dysfunction is one of the major causes of heart failure with preserved ejection fraction. Aim To assess left ventricular systolic and diastolic functions in children with severe acute malnutrition using tissue Doppler imaging technique and to evaluate the effect of nutritional rehabilitation. Patients and Methods A follow-up case-control study conducted on 60 severely malnourished children (WHZ < -3SD) and 120 age and sex-matched healthy children as a control group. Tissue Doppler imaging (TDI) was done for all included malnourished children at admission and for control to measure left ventricular systolic and diastolic functions. Nutritional rehabilitation was done according to WHO protocol and tissue doppler was repeated after rehabilitation when (WHZ > -2SD) to detect any changes in systolic or diastolic functions. Results Systolic function was normal in malnourished children and control. Grade I diastolic dysfunction was detected in 40% and grade II in 30% of severely malnourished children in comparison to 100% normal diastolic function in control group. No correlations between diastolic dysfunction and either anthropometric measurements, electrolyte disturbances or Hb% in malnourished children before nutritional rehabilitation. Mortality from sepsis with associated ventricular dysfunction grade II documented in 3.3% of malnourished children. After nutritional rehabilitation diastolic function improved significantly as 65.6% of children attained normal diastolic function, 31% grade1 and 3.4% grade II. Positive correlations between diastolic function and WAZ, HAZ, WHZ and MUAC after rehabilitation. Conclusion Severe acute malnutrition affects diastolic function in children which is reversible in most of these cases with rehabilitation. TDI is an easy and practical method for detection and follow-up of ventricular function in malnourished children.

Global left-ventricular function by tissue Doppler imaging in pediatric dialysis patients

2008 ◽  
Vol 23 (5) ◽  
pp. 779-785 ◽  
Author(s):  
Tayfun Uçar ◽  
Ercan Tutar ◽  
Fatoş Yalçınkaya ◽  
Nilgün Çakar ◽  
Z. Birsin Özçakar ◽  
...  
Keyword(s):  
Left Ventricular Function ◽  
Ventricular Function ◽  
Tissue Doppler Imaging ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Dialysis Patients ◽  
Pediatric Dialysis ◽  
Global Left Ventricular Function ◽  
Pediatric Dialysis Patients
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