Autoantibodies as risk factors for threatened miscarriage in women with early pregnancy loss

2021 ◽  
Vol 8_2021 ◽  
pp. 94-101
Author(s):  
Menzhinskaya I.V. Menzhinskaya ◽  
Ionanidze T.B. Ionanidze ◽  
Van’ko L.V. Van’ko ◽  
Tetruashvili N.K. Tetruashvili N ◽  
Krechetova L.V. Krechetova ◽  
...  
2019 ◽  
Vol 70 (11) ◽  
pp. 3818-3823
Author(s):  
Mihai Cristian Dumitrascu ◽  
Madalina Iliescu ◽  
Razvan Cosmin Petca ◽  
Florica Sandru ◽  
Claudia Mehedintu ◽  
...  

The chemical pregnancy is an early pregnancy loss occurring shortly after implantation. 50-75% of all miscarriages are considered to be chemical pregnancies. Although the pregnancy test is positive, the fetus cannot be detected on ultrasounds; it can be asymptomatic or it can have menstrual-like cramping and bleeding. There are numerous risk factors associated with miscarriage, such as: epidemiological, genetic, anatomical, endometrial, endocrine and immune factors, infections, inherited thrombophilia and antiphospholipid syndrome. Many drugs are related with spontaneous miscarriage, significant evidence being found for nonsteroidal anti-inflammatory drugs, inhaled corticosteroids, antidepressant medication, antiepileptic and antihypertensive drugs, the artemisinin-based combination therapy and for the diclofenac/misoprostol combination. Besides the common diseases like asthma, chronic hypertension, chronic kidney disease, thyroid disorders, diabetes mellitus, polycystic ovary syndrome and rheumatoid arthritis, there was also found a higher correlation with the risk of miscarriage for the Zika Virus infection. In conclusion, chemical pregnancy is a type of early pregnancy loss which usually doesn�t need prevention, associated with multiple risk factors.


2019 ◽  
Vol 124 ◽  
pp. 18-23 ◽  
Author(s):  
A.M. de Mestre ◽  
B.V. Rose ◽  
Y.M. Chang ◽  
D.C. Wathes ◽  
K.L.P. Verheyen

Epidemiology ◽  
1990 ◽  
Vol 1 (5) ◽  
pp. 382-385 ◽  
Author(s):  
Allen J. Wilcox ◽  
Clarice R. Weinberg ◽  
Donna D. Baird

2014 ◽  
Vol 46 ◽  
pp. 16-16 ◽  
Author(s):  
B. Rose ◽  
M. Firth ◽  
B. Morris ◽  
C. Nicholson ◽  
K. Verheyen ◽  
...  

2000 ◽  
Vol 95 (4) ◽  
pp. 519-524 ◽  
Author(s):  
WILLIANNE L. D. M. NELEN ◽  
HENK J. BLOM ◽  
ERIC A. P. STEEGERS ◽  
MARTIN DEN HEIJER ◽  
CHRIS M. G. THOMAS ◽  
...  

2019 ◽  
Vol 70 (11) ◽  
pp. 3818-3823
Author(s):  
Mihai Cristian Dumitrascu ◽  
Madalina Iliescu ◽  
Razvan Cosmin Petca ◽  
Florica Sandru ◽  
Claudia Mehedintu ◽  
...  

The chemical pregnancy is an early pregnancy loss occurring shortly after implantation. 50-75% of all miscarriages are considered to be chemical pregnancies. Although the pregnancy test is positive, the fetus cannot be detected on ultrasounds; it can be asymptomatic or it can have menstrual-like cramping and bleeding. There are numerous risk factors associated with miscarriage, such as: epidemiological, genetic, anatomical, endometrial, endocrine and immune factors, infections, inherited thrombophilia and antiphospholipid syndrome. Many drugs are related with spontaneous miscarriage, significant evidence being found for nonsteroidal anti-inflammatory drugs, inhaled corticosteroids, antidepressant medication, antiepileptic and antihypertensive drugs, the artemisinin-based combination therapy and for the diclofenac/misoprostol combination. Besides the common diseases like asthma, chronic hypertension, chronic kidney disease, thyroid disorders, diabetes mellitus, polycystic ovary syndrome and rheumatoid arthritis, there was also found a higher correlation with the risk of miscarriage for the Zika Virus infection. In conclusion, chemical pregnancy is a type of early pregnancy loss which usually doesn�t need prevention, associated with multiple risk factors.


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