ESTROGENIC ACTIVITY OF LAMBDA-CYHALOTHRIN IN THE MCF-7 HUMAN BREAST CARCINOMA CELL LINE

2007 ◽  
Vol preprint (2008) ◽  
pp. 1
Author(s):  
Meirong Zhao ◽  
Ying Zhang ◽  
Weiping Liu ◽  
Chao Xu ◽  
Lumei Wang ◽  
...  
Nature ◽  
1974 ◽  
Vol 252 (5480) ◽  
pp. 247-250 ◽  
Author(s):  
CHARLES M. MCGRATH ◽  
PETER M. GRANT ◽  
HERBERT D. SOULE ◽  
TERRY GLANCY ◽  
MARVIN A. RICH

2011 ◽  
Vol 26 (6) ◽  
pp. 539-551 ◽  
Author(s):  
Milena Ignatova ◽  
Lilia Yossifova ◽  
Elena Gardeva ◽  
Nevena Manolova ◽  
Reneta Toshkova ◽  
...  

The antiproliferative activity of electrospun mats of poly(L-lactide- co-D,L-lactide) (coPLA) containing quaternized chitosan (QCh) and/or doxorubicin hydrochloride (DOX) was evaluated against the Michigan Cancer Foundation-7(MCF-7) human breast carcinoma cell line. QCh- and DOX-containing nanofibrous mats possess good antiproliferative activity and decrease considerably the viability of the MCF-7 cells for the different periods of cell incubation as confirmed by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Fluorescent microscopy analyses and scanning electron microscopy observations revealed that apoptosis was one of the major mechanisms of MCF-7 cell death induced by the QCh- and DOX-containing mats.


Author(s):  
J. Russo ◽  
R.H. Bradley

The epithelial cells of the normal human breast are tightly joined by junctional complexes composed of tight junctions, intermediate junctions, and desmosomes. Similar junctions have been reported in several types of breast carcinoma. In the present paper we report on the junctional systems observed in a human breast carcinoma cell line (MCF-7) (1).MCF-7 cells cultured in Eagle's minimum essential medium, after 40-160 transfers were fixed simultaneously in glutaraldehyde and osmium according to the method of Hirsch and Fedorko (2), and were stained in uranyl acetate in block. After dehydration, the samples were detached with propylene oxide and embeded in Epon-Araldite (3). Sections were examined in an Hitachi HU-11A electron microscope after staining with uranyl acetate.


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