Case: We describe a case of 72-year-old male with dedifferentiated chondrosarcoma with osteosarcomatous
and epithelioid (squamous) dedifferentiation. As first described in the literature by Dahlin and Beabout, a
well-differentiated benign chondral lesion abruptly juxtaposed to a high-grade non-cartilaginous component
is the classical definition of a chondrosarcoma [1]. The non-cartilaginous component is typically an
osteosarcoma, fibrosarcoma or malignant fibrous histiocytoma with rare instances of leiomyosarcoma, giant
cell tumor and rhabdomyosarcoma [2].
Conclusion: We report our rare instance of squamous dedifferentiation of a dedifferentiated
chondrosarcoma along with other five cases that have been reported so far in the literature
Dedifferentiated Chondrosarcoma of the Larynx: A Case Report and Review of the Literature
