Background: The aim of the study is evaluation of the possible role of the
scintigraphic estimation of the relative liver perfusion in diagnosis and the
choice of treatment of liver carcinomas. Material and methods: Hepatic
perfusion index was obtained by dynamic scintigraphy in 126 patients.
Results: In the control group values did not differ from the value in the
patients with benign tumors (p>0.05). However, in hepatocellular carcinoma
and liver metastases of different tumors, HPI values were significantly
decreased in comparison to controls and benign tumors (p<0.01), but they
didn?t differ between themselves (p>0.05). The values were especially low in
the patients with malignant diseases in the liver accosciated with vascular
disturbances in the portal system. Conclusion: HRA could be easily done
during the different conventional nuclear medicine methods. It can be an
useful method for the assessment of different degrees of hemodynamic
alterations in portal system, for differential diagnosis of benign and
malignant liver tumors, as well as for assessment of the liver tissue and
tumor perfusion, which might be helpful in the decision making for the
undertaking of intraarterial (radionuclide, chemotherapy etc.) therapy.
Role of percutaneous image-guided ablation of malignant liver tumors: global trends and Croatian perspective
