scholarly journals Optimization of the future remnant liver: review of the current strategies in Europe

2021 ◽  
Vol 10 (3) ◽  
pp. 350-363
Author(s):  
Riccardo Memeo ◽  
Maria Conticchio ◽  
Emmanuel Deshayes ◽  
Silvio Nadalin ◽  
Astrid Herrero ◽  
...  
Author(s):  
Klaus STEINBRÜCK ◽  
Jefferson ALVES ◽  
Reinaldo FERNANDES ◽  
Marcelo ENNE ◽  
Lúcio Filgueiras PACHECO-MOREIRA

BACKGROUND: Portal vein embolization is an accepted procedure that provides hypertrophy of the future remnant liver in order to reduce post-hepatectomy complications. AIM: To present a series submitted to portal vein embolization using an adapted hysterosalpingography catheter via transileocolic route. METHODS: Were performed right portal branch embolization in 19 patients using hysterosalpingography catheter. For embolizing the vessel, was used Gelfoam(r) powder with absolute alcohol solution. Indications for hepatectomy were colorectal liver metastases in all cases. RESULTS: An adequate growth of the future remnant liver was achieved in 15 patients (78.9%) and second time hepatectomy could be done in 14 (73.7%). In one patient (5.2%), tumor progression prevented surgery. One patient presented acute renal failure after portal embolization. CONCLUSIONS: The hysterosalpingography catheter is easy to handle and can be introduced into the portal vein with a wire guide. There were no major post-embolization complication. Its use is safe, cheap and effective.


Author(s):  
Yu. N. Likar ◽  
D. G. Akhaladze ◽  
A. G. Rumyantsev

Liver resection remains one of the most important option in combined treatment for liver tumors; however, it harbors the risk of developing posthepatectomy liver failure. The principal risk is associated with the quality and quantity of the future remnant liver. Therefore, preoperative assessment of the future remnant liver is essential in patients scheduled for major hepatectomy. Technetium-99m-mebrofenin hepatobiliary scintigraphy is increasingly applied for the quantitative assessment of liver function before major liver resection.


2010 ◽  
Vol 17 (8) ◽  
pp. 2081-2089 ◽  
Author(s):  
Thierry de Baere ◽  
Christophe Teriitehau ◽  
Frederic Deschamps ◽  
Laurence Catherine ◽  
Pramod Rao ◽  
...  

2021 ◽  
pp. 000313482110110
Author(s):  
Masashi Kudo ◽  
Naoto Gotohda ◽  
Motokazu Sugimoto ◽  
Masaru Konishi ◽  
Shinichiro Takahashi ◽  
...  

Background The liver-to-spleen signal intensity ratio (LSR) on magnetic resonance imaging with gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid has been used as a parameter to assess liver function. LSR of the future remnant liver region (FR-LSR) is included in preoperative assessment of regional liver function. The aim of this study was to investigate the predictability of post-hepatectomy liver failure (PHLF) by FR-LSR. Methods Between May 2013 and May 2019, 127 patients underwent standardized EOB-MRI for diagnosis of liver tumor before major hepatectomy. The FR-LSR on EOB-MRI was calculated by a semiautomated three-dimensional volumetric analysis system. The cutoff value of FR-LSR in association with clinically relevant PHLF was determined according to the areas under the receiver operating characteristic curves. Then, FR-LSR and clinical variables were analyzed to assess the risk of clinically relevant PHLF. Results In patients with preoperative biliary drainage, metastatic liver tumor, estimated future remnant liver volume <50%, biliary reconstruction, operation time ≥ 480 min, estimated blood loss ≥ 1000 g, blood transfusion and a FR-LSR < 2.00 were associated with clinically relevant PHLF ( P < .05 for all) in univariable analysis. The liver-to-spleen signal intensity ratio of the future remnant liver region < 2.00 was the only independent risk factor for clinically relevant PHLF in multivariable risk analysis (OR, 27.90; 95% CI: 7.99-136.40; P < .05). Discussion The present study revealed that FR-LSR calculated using a 3-dimensional volumetric analysis system was an independent risk factor for clinically relevant PHLF. The liver-to-spleen signal intensity ratio of the future remnant liver region might be a reliable preoperative parameter in liver functional assessment, enabling safe performance of major hepatectomy.


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