The role of superficial layer cells in maintenance of articular cartilage surface integrity

2017 ◽  
Vol 2 ◽  
pp. 23-23
Author(s):  
John D. Sandy ◽  
Anna Plaas
2015 ◽  
Vol 6 (7) ◽  
pp. 2398 ◽  
Author(s):  
Nicolai Brill ◽  
Jörn Riedel ◽  
Björn Rath ◽  
Markus Tingart ◽  
Holger Jahr ◽  
...  

2017 ◽  
Vol 69 (8) ◽  
pp. 625-629 ◽  
Author(s):  
Pei-tong Jia ◽  
Xing-lin Zhang ◽  
Hai-ning Zuo ◽  
Xing Lu ◽  
Peng-zhou Gai

Author(s):  
M H Naka ◽  
Y Morita ◽  
K Ikeuchi

In this work, the hypothesis that water content and substances present on the articular surface play an important role in lubrication through the formation of a layer with a high content of water on the articular surface is analysed. The hydrophilic properties of proteoglycans exposed at the articular surface and hydration of tissue are the main responsible factors for the formation of this layer. The role of the articular surface in the frictional characteristics of articular cartilage was examined using specimens (femoral condyles of pigs) with intact and wiped surfaces tested in intermittent friction tests. Results indicated that the intact condition presented low friction in comparison with the wiped condition. The measured water loss of the articular cartilage after sliding and loading indicated a gradual decrease in the water content as the time evolved, and rehydration was observed after the submersion of unloaded specimens in the saline bath solution. Micrographic analyses indicated the presence of a layer covering the articular surface, and histological analyses indicated the presence of proteoglycans in this superficial layer. The hydration of the cartilage surface layer and proteoglycan in this layer influence lubrication.


2001 ◽  
Vol 26 (3) ◽  
pp. 254-260 ◽  
Author(s):  
S.Y. Hu ◽  
S. Wang ◽  
R.T. Zuo ◽  
K.L. Wang ◽  
L. Qin

Seven healthy mature rabbits were used to study both the surface morphology of the meniscus using both transmission electronmicroscopy (TEM) and scanning electronmicroscopy (SEM) and articular cartilage of the femoral condyle using SEM. Results showed that the membrane covering the meniscus was structurally the extension of synovial membrane of the knee joint capsule. Additionally, the presence of canal-like openings over the membranous surface to the meniscus was noted, which were absent over the articular cartilage surface. Key words: transmission and scanning electronmicroscopy, meniscus, articular cartilage, rabbits


Author(s):  
Jonathan T. Henderson ◽  
Corey P. Neu

Osteoarthritis (OA) is a disabling disease, commonly thought of as the “wear and tear” of articular cartilage, afflicting 27 million Americans [1]. Multiple (e.g. biomechanical and biochemical) factors [2] contribute to maintenance of healthy joints through chondrocyte and extracellular matrix interactions. Interestingly, volumetric contractions of nuclei exhibit a zonal dependence [3], suggesting that nuclear mechanics may play a key role in the maintenance of healthy tissue by mechanically-mediated pathways.


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