Introduction. Lipoma arborescens is a rare, tumor-like lesion commonly
involving synovial joints and less commonly bursae and synovial tendon
sheaths. Case Outline. We report a case of a 12-year-old boy with symmetric
involvement of the bicipitoradial bursae, synovial sheaths of extensor
compartments of both hands and medial ankles. The diagnosis of polyarticular
lipoma arborescens was proposed on magnetic resonance (MR) imaging and this
diagnosis was histologically proven after biopsy of the bursae and later by
open surgery of the synovial sheath of the right ankle tendons. Literature
search was performed and twelve cases with polyarticular involvement were
analyzed. Lipoma arborescens commonly involves suprapatellar recess of the
knee and very rarely other joints or bursae. Histological analysis revealed
an accompanying non-necrotizing granulomatous synovial inflammation.
Conclusion. Polyarticular lipoma arborescens is a rare entity and symmetrical
involvement of the joints other than the knees is exceedingly rare. MR
imaging plays a significant role in the diagnostic protocol, and the
characteristic fatty signal on MR imaging is highly suggestive of lipoma
arborescens.