scholarly journals Synthesis, Characterization of some New 1, 3, 4-Oxadiazole derivatives based on 4- amino benzoic acid

2016 ◽  
Vol 13 (2) ◽  
pp. 289-297
Author(s):  
Shatha Al-Zobaydi ◽  
◽  
Bushra Karim ◽  
Sanaa Al-Sahib ◽  
Ban Ismael ◽  
...  
Keyword(s):  
Benzoic Acid ◽  
Oxadiazole Derivatives ◽  
Amino Benzoic Acid

scholarly journals Synthesis and Characterization of some New 1,3,4-Oxadiazole derivatives based on 4-amino benzoic acid

2016 ◽  
Vol 13 (4) ◽  
pp. 762-769
Author(s):  
Baghdad Science Journal
Keyword(s):  
Schiff Base ◽  
Benzoic Acid ◽  
Spectral Data ◽  
1H Nmr ◽  
Synthesis And Characterization ◽  
Oxadiazole Derivatives ◽  
Ft Ir ◽  
Amino Benzoic Acid

Various of 2,5- disubstituted 1,3,4-oxadiazole (Schiff base, ?- lactam and azo) were synthesized from 2,5-di (4,4?-amino-1,3,4-oxadiazole which usequently synth-esized from mixture of 4- amino benzoic acid and hydrazine arch of polyphosphorus acid. The synthesized compounds were cherecterized by using some spectral data (UV, FT-IR , and 1H-NMR)

scholarly journals Synthesis, Characterization of some New 1, 3, 4-Oxadiazole derivatives based on 4- amino benzoic acid

2016 ◽  
Vol 13 (2) ◽  
pp. 289-297
Author(s):  
Baghdad Science Journal
Keyword(s):  
Schiff Base ◽  
Benzoic Acid ◽  
Spectral Data ◽  
1H Nmr ◽  
Oxadiazole Derivatives ◽  
Ft Ir ◽  
Amino Benzoic Acid

In this research various of 2,5-disubstituted 1,3,4-oxadiazole (Schiff base, oxo-thiazolidine , and other compounds) were synthesized from 2,5-di(4,4?- amino-1,3,4-oxadiazole ) which use quently synthesized from mixture of 4-amino benzoic acid and hydrazine in the presence of polyphosphorus acid. The synthesized compounds were characterized by using some Spectral data (UV, FT-IR, and 1H-NMR).

Synthesis and Characterization of some new Schiff base Compounds derived from 4-Amino benzoic acid and study their Biological activity

2019 ◽  
Vol 12 (5) ◽  
pp. 2207
Author(s):  
Mahdi F. Radi ◽  
Suhair S. Husain ◽  
Abrar Natek Mohammed Zaki ◽  
Alaa A. Sultan ◽  
Wejdan Mahmmod Hamed ◽  
...  
Keyword(s):  
Biological Activity ◽  
Schiff Base ◽  
Benzoic Acid ◽  
Synthesis And Characterization ◽  
Amino Benzoic Acid

scholarly journals Synthesis and In Vitro Evaluation of C-methylcalix[4]resorcinaryl octacinnamate and C-methylcalix[4]resorcinaryl octabenzoate as the Sunscreen

2017 ◽  
Vol 17 (1) ◽  
pp. 63 ◽  
Author(s):  
Budiana I Gusti M. Ngurah ◽  
Jumina Jumina ◽  
Chairil Anwar ◽  
Sunardi Sunardi ◽  
Mustofa Mustofa
Keyword(s):  
Benzoic Acid ◽  
Mtt Assay ◽  
13C Nmr ◽  
Benzoyl Chloride ◽  
Spectroscopic Method ◽  
Activity Test ◽  
Acid Catalyzed ◽  
Amino Benzoic Acid

The present study was aimed to synthesize and evaluate sunscreen activity of C-methylcalix[4]resorcinaryl octacinnamate and C-methylcalix[4]resorcinaryl octabenzoate. The target compounds were synthesized in 2 steps. They were a synthesis of C-methylcalix[4]-resorcinarene via acid catalyzed the condensation of resorcinol and acetaldehyde by using HCl catalyst, followed by esterification using cinnamoyl chloride and benzoyl chloride. The characterization of the target compounds was performed by IR, 1H-NMR, 13C-NMR, and LC-MS spectrometers. The sunscreen activity test was conducted by spectroscopic method and MTT-assay. Commercial sunscreen p-amino benzoic acid (PABA) was used as a comparator to the MTT assay. The sunscreen activity test used spectroscopic showed that C-methylcalix[4]resorcinaryl octacinnamate and C-methylcalix[4]resorcinaryl octabenzoate can absorb the ultraviolet radiation between 280 and 320 nm (UV-B) with the maximum absorption at 290 nm (ε = 31.535 M-1 cm-1) and 282 nm (ε = 42.217 M-1 cm-1), respectively. The results of MTT-assay indicated that the IC50 of C-methylcalix[4]resorcinaryl octacinnamate, C-methylcalix[4]resorcinaryl octabenzoate and PABA are 12.006, 20.568 and 12.564 ppm, respectively, it means that the order of sunscreen activity is C-methylcalix-[4]resorcinaryl octacinnamate, PABA and C-methylcalix[4]resorcinaryl octabenzoate.

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