scholarly journals Determination of azole antifungal drug resistance mechanisms involving Cyp51A gene in clinical isolates of Aspergillus fumigatus and Aspergillus niger

2016 ◽  
Author(s):  
Rajendran, M. ◽  
Khaithir, T. M. N. ◽  
Santhanam, J.
Keyword(s):  
Drug Resistance ◽  
Aspergillus Niger ◽  
Aspergillus Fumigatus ◽  
Resistance Mechanisms ◽  
Antifungal Drug ◽  
Clinical Isolates ◽  
Antifungal Drug Resistance

scholarly journals Environmental Isolates of Azole-Resistant Aspergillus fumigatus in Germany

2015 ◽  
Vol 59 (7) ◽  
pp. 4356-4359 ◽  
Author(s):  
Oliver Bader ◽  
Jana Tünnermann ◽  
Anna Dudakova ◽  
Marut Tangwattanachuleeporn ◽  
Michael Weig ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Aspergillus Fumigatus ◽  
Antifungal Drug ◽  
Clinical Samples ◽  
Environmental Isolates ◽  
Northern Germany ◽  
Content Type ◽  
Antifungal Drug Resistance ◽  
The World

ABSTRACTAzole antifungal drug resistance inAspergillus fumigatusis an emerging problem in several parts of the world. Here we investigated the distribution of such strains in soils from Germany. At a general positivity rate of 12%, most prevalently, we found strains with the TR34/L98H and TR46/Y121F/T289A alleles, dispersed along a corridor across northern Germany. Comparison of the distributions of resistance alleles and genotypes between environment and clinical samples suggests the presence of local clinical clusters.

Emerging Antifungal Drug Resistance in Aspergillus fumigatus and Among Other Species of Aspergillus

2018 ◽  
Vol 12 (3) ◽  
pp. 105-111 ◽  
Author(s):  
Takahito Toyotome ◽  
Daisuke Hagiwara ◽  
Hiroki Takahashi ◽  
Akira Watanabe ◽  
Katsuhiko Kamei
Keyword(s):  
Drug Resistance ◽  
Aspergillus Fumigatus ◽  
Antifungal Drug ◽  
Antifungal Drug Resistance
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