scholarly journals Hemodynamic changes in superficial arteriovenous malformation surgery measured by intraoperative ICG fluorescence videoangiography with FLOW 800 software

2020 ◽  
Author(s):  
Xun Ye ◽  
Liang Wang ◽  
Ming-tao Li ◽  
Xiao-lin Chen ◽  
Hao Wang ◽  
...  

Abstract To analyze the application of intraoperative indocyanine green (ICG) angiography with FLOW 800 software in arteriovenous malformation (AVM) surgeries. Data on 17 patients undergoing surgery with ICG fluorescence were collected. To analyze the hemodynamic features of AVM and the influence on the peripheral cortex of AVM resection, we assessed the following hemodynamic parameters: maximum intensity, slope of rise, time to half-maximal fluorescence, and transit time from arteries to veins. In the 17 superficial AVMs studied, the time delay color mode of FLOW 800 software was superior to the traditional playback mode for identifying feeding arteries, draining veins, and their relation to normal cortical vessels.The maximum fluorescence intensity and slope of the ICG fluorescence curve of feeder arteries and draining veins were higher than those of normal peripheral vessels (P < 0.05). The transit times in AVMs were significantly shorter than those in normal peripheral vessels (P < 0.05).After AVM resection, cerebral flow increased in the cortex, and local cycle time become longer, although the differences were not significant (P > 0.05). Hemodynamic parameter analysis provided quality guidance for the resection of AVMs and could also be used in estimating changes in blood flow in the local cortex to identify abnormal hyperperfusion and residual nidus.

2020 ◽  
Author(s):  
Xun Ye ◽  
Liang Wang ◽  
Ming-tao Li ◽  
Xiao-lin Chen ◽  
Hao Wang ◽  
...  

Abstract Background: Arteriovenous malformation(AVM) have long-term “blood stealing” characteristics, which result in complicated hemodynamic features. To analyze the application of intraoperative indocyanine green angiography with FLOW 800 software in AVM surgeries.Methods: Data on 17 patients undergoing surgery with ICG fluorescence were collected. To analyze the hemodynamic features of AVM and the influence on the peripheral cortex of AVM resection, we assessed the following hemodynamic parameters: maximum intensity, slope of rise, time to half-maximal fluorescence, and transit time from arteries to veins.Results:In the 17 superficial AVMs studied, the time delay color mode of FLOW 800 software was superior to the traditional playback mode for identifying feeding arteries, draining veins, and their relation to normal cortical vessels.The maximum fluorescence intensity and slope of the ICG fluorescence curve of feeder arteries and draining veins were higher than those of normal peripheral vessels (P < 0.05). The transit times in AVMs were significantly shorter than those in normal peripheral vessels (P < 0.05).After AVM resection, cerebral flow increased in the cortex, and local cycle time become longer, although the differences were not significant (P > 0.05).Conclusions:Hemodynamic parameter analysis provided quality guidance for the resection of AVMs and could also be used in estimating changes in blood flow in the local cortex to identify abnormal hyperperfusion and residual nidus.


2013 ◽  
Vol 10 (2) ◽  
pp. 231-239 ◽  
Author(s):  
Vincent Prinz ◽  
Nils Hecht ◽  
Naoki Kato ◽  
Peter Vajkoczy

Abstract BACKGROUND: FLOW 800 delivers a color-coded map for snapshot visualization of the temporal distribution dynamics after indocyanine green angiography with post hoc calculation of FLOW 800-specific hemodynamic parameters. However, the value of these parameters regarding quantitative flow assessment remains unclear. OBJECTIVE: To determine the value of FLOW 800-specific hemodynamic parameters in neurosurgical patients that permit assessment of hemodynamic changes within the microcirculation and macrocirculation. METHODS: FLOW 800 was performed in 25 patients undergoing superficial temporal artery to middle cerebral artery bypass grafting and in 5 patients undergoing high- or intermediate-flow bypass grafting. The time to half-maximum fluorescence (t1/2max) and the cerebral blood flow index were calculated in the recipient vessel (macrocirculation) and the cortical territory (microcirculation) surrounding the anastomosis. For further evaluation, FLOW 800-specific hemodynamic parameters were compared with cortical laser speckle imaging and quantitative Doppler flow within the graft. RESULTS: FLOW 800 provided color-coded information on the temporospatial distribution dynamics of the dye with excellent assessment of bypass patency. In the recipient vessel and in the cortical territory surrounding the anastomosis, FLOW 800 detected hemodynamic changes after superficial temporal artery to middle cerebral artery bypass grafting in terms of a significant decrease in t1/2max and increase in cerebral blood flow index. Interestingly, comparison of t1/2max with semiquantitative laser speckle imaging-specific cortical perfusion within the microcirculation demonstrated poor agreement, and neither t1/2max nor the cerebral blood flow index within the graft correlated with quantitative graft flow assessed by Doppler. CONCLUSION: FLOW 800 may detect procedure-related hemodynamic changes within the microcirculation and macrocirculation but should not be used as a stand-alone tool for quantitative flow assessment.


2003 ◽  
Vol 60 (4) ◽  
pp. 435-442
Author(s):  
Gordana Arandjelovic-Minic

Progresson of extracranial carotid disease is considered to be significant independent predictor in the evaluation of individual cerebrovascular prognosis. Doppler ultrasonography is a useful screening method in the diagnosis and evaluation of extracranial carotid disease. The aim of this study was to establish the most sensitive hemodynamic parameter of Doppler-ultrasonographic spectral analysis in clinical evaluation of extracranial carotid disease. Investigation included 90 patients (of both sexes) in hospital and outpatient clinic care. Spectral analysis (M-scanning technique) was used for the evaluation of hemodynamic status of carotid sinus, including the following parameters: Pourcelot (A-D/A), Gosling (A/B) and Mol (A/D) resistance parameters. After statistical processing the results of the research affirmed hemodynamic parameters' values and correlation between Pourcelot hemodynamic parameter and the degree of carotid stenosis ?=0,59 for all patients, and ?=0,58 for patients with pathological values. Correlation between Mol parameter and the degree of carotid stenosis was ?=0,50 for all patients, and ?=0,57 for patients with pathological values. Gosling parameter was not significantly different in mean value and was present in all three groups. Functional relationship between the degree of carotid stenosis and each of hemodynamic parameters was established. It was concluded that Pourcelot and Mol parameters were significant indicators of asimptomatic carotid disease, but Pourcelot parameter was considered as a more sensitive indicator in the evaluation of extracranial carotid disease.


2017 ◽  
Vol 11 (1) ◽  
pp. 88-96
Author(s):  
Fang-Ting Chen ◽  
An-Hsun Chou ◽  
Chun-Yu Chen ◽  
Pei-Chi Ting ◽  
Ming-Wen Yang ◽  
...  

Background and Objective: Hemodynamic consequences during video-assisted thoracoscopic surgery (VATS) with decortication during empyema drainage are unclear. The aim of the study was to assess the perioperative hemodynamic changes decortication during empyema drainage. Methods: A prospective study enrolled 23 patients with empyema who underwent decortication. Hemodynamic parameters were continuously obtained at 15 time points: supine two lung ventilation after induction, lateral decubitus position and two lung ventilation, lateral decubitus position and one-lung ventilation, every 5 min after decortication upto 60 minutes and at the end of surgery. We divided patients into three groups according to microorganisms, group 1: patients with no growth of organism; group 2: patients with staphylococcus aureus and pseudomonas; group 3: patients with streptococcus, yeast and fungus, gram-positive bacilli, and mycobacterium tuberculosis. The hemodynamic variables were recorded by the third-generation Vigileo/FloTracTM system and variables for each time interval were compared with the baseline by Wilcoxon Signed Ranks Test. Results: In group 1, hemodynamic parameters showed no significant changes over time. However, in group 2 and 3, both CO and CI increased 10 to 15 minutes after decortication and remained elevated during the remainder of surgery. However, SVR and SVRI decreased 10 to 15 minutes after decortication in both groups, especially, with a more significant decrease noted in group 2 than group 3. Conclusion: Close perioperative hemodynamic monitoring during decortication in empyema patients is required because of potential hemodynamic disturbances especially patients with toxic microorganisms.


2019 ◽  
Vol 6 (1) ◽  
pp. 17
Author(s):  
Caterina Di Bella ◽  
Luca Lacitignola ◽  
Laura Fracassi ◽  
Despoina Skouropoulou ◽  
Antonio Crovace ◽  
...  

Pneumoperitoneum may induce important hemodynamic alterations in healthy subjects. Pulse pressure variation (PPV) is a hemodynamic parameter able to discriminate preload dependent subjects. Anesthesia records of dogs undergoing laparoscopy were retrospectively evaluated. The anesthetic protocol included acepromazine, methadone, propofol and isoflurane administered with oxygen under mechanical ventilation. The hemodynamic parameters were considered five minutes before (BASE) and ten minutes after (P10) the pneumoperitoneum. Based on the cardiac index (CI) variation, at P10, dogs were classified as sensitive (S group, CI ≤ 15%) and non-sensitive (NO-S group). Data were analyzed with the ANOVA test and the ROC curve (p < 0.05). Fifty-five percent of dogs (S) had a reduction of CI ≥ 15% at P10 (2.97 ± 1.4 L/min/m2) compared to BASE (4.32 ± 1.62 L/min/m2) and at P10 in the NO-S group (4.51 ± 1.41 L/min/m2). PPV at BASE was significantly higher in the S group (22.4% ± 6.1%) compared to the NO-S group (10.9% ± 3.3%). The ROC curve showed a threshold of PPV > 16% to distinguish the S and NO-S groups. PPV may be a valid predictor of the hemodynamic response to pneumoperitoneum in dogs. A PPV > 16% can identify patients that may require fluid administration before the creation of pneumoperitoneum.


2011 ◽  
Vol 18 (11) ◽  
pp. 1556-1557 ◽  
Author(s):  
Sukhdeep S. Jhawar ◽  
Yoko Kato ◽  
Junpei Oda ◽  
Daikichi Oguri ◽  
Hirotoshi Sano ◽  
...  

2020 ◽  
Author(s):  
Nasibova EM

Aim: Optimization of anesthetic benefits in one-day surgery by using propofol. Materials: The study included 58 patients operated on for inguinal and umbilical hernias, dropsy of testicular membranes, cryptorchidism, varicocele, hemangiomas of various localization, phimosis and paraphimosis. Depending on the age of the children, this group was divided into 3 subgroups: IA (n=12) age 0-3 years, IB (n=33)-4-7 years old and IC (n=13)-8-16 years old. This study was carried out in five stages. Results: Basically, in all age groups, the performance of the cardiovascular system remained at the level of the initial values, however, certain hemodynamic changes characterizing the effect of propofol were revealed. The characteristic imbalances of the main parameters of the volumetric blood flow indicate hemodynamic stress that occurred against the background of the action of propofol in all groups during the induction of anesthesia. All this clearly and objectively characterizes the vasodilating properties of propofol, as a factor that causes the most typical changes in central hemodynamics. Indices of external respiration after premedication at the induction stage tended to decrease and indicated moderate hypoventilation. At the traumatic stage of the study, an increase in BH was observed, which was associated with the appearance of pain. Thus, propofol induction proceeded with a hypodynamic type of blood circulation. At the most traumatic time of the operation, despite an increase in the dose of fentanyl, hemodynamic parameters were hyperdynamic type of blood circulation, associated with insufficient relief of the pain component. And an increase in the dose of fentanyl led to the development of hypoventilation with subsequent apnea, which required mechanical ventilation. Thus, analyzing the results obtained, it should be noted that anesthesia during 'small' surgical interventions with propofol and fentanyl is not an optimal method. Since at the most traumatic time of the operation, it is necessary to increase the dose of fentanyl, and this leads to hypoventilation with the subsequent development of apnea, which requires correction. Conclusion: Analyzing the results obtained, it should be noted that anesthesia during "small" surgical interventions with propofol and fentanyl is not an optimal method. Since at the most traumatic time of the operation, it is necessary to increase the dose of fentanyl, and this leads to hypoventilation with the subsequent development of apnea, which requires correction.


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