scholarly journals Imaging findings and differential diagnosis of hepatic sinusoidal occlusion syndrome and Budd-Chiari syndrome

Author(s):  
Cui yu Jia ◽  
Da wei Zhao ◽  
Ji liang Feng ◽  
Rui li Li ◽  
Xin xin Wang ◽  
...  

Abstract Objective To retrospectively analyze the clinical and imaging manifestations differential points between hepatic sinusoidal obstruction syndrome (SOS) and Budd-Chiari syndrome (BCS). Material The clinical symptoms, laboratory examination and imaging findings of 15 cases of hepatic sinusoidal obstruction syndrome and 33 cases of Budd-Chiari syndrome were statistically analyzed, find the identification points. The study used the Fisher test, P values of 0.05 or less were considered to indicate significant differences. The retrospective study was approved by the hospital's ethics committee. Results Laboratory tests: There were significant differences in total protein reduction rate (66.7% vs 9.1%, p༜0.01), albumin reduction rate (66.7% vs 9.1%, p༜0.01), Gamma-glutamyltransferase elevation rate (100% vs 6.1%, P༜0.01), alkaline phosphatase elevation rate (60% vs 6.1%, p༜0.01), and abnormal rate of prothrombin time (100% vs 21.2%, p༜0.01) between the two groups (BCS vs SOS). It also indicates that the liver function of SOS patients is more seriously impaired. Image findings: The following image findings were observed significant more frequently in SOS than in BCS and were statistically significant: gallbladder wall thickening (66.7% vs 78.2%, p༜0.01), ascites (80% vs 27.3%, p༜0.01), cloverleaf or claw-like shapes (80% vs 0%, p༜0.01). The following images appeared more frequently in BCS than in BCS and were statistically significant: caudate lobe enlargement (33.3% vs 75.8%, p༜0.01), collateral circulation (46.7% vs 93.9%, p༜0.01), diffuse patchy enhancement (20% vs 93.9%, p༜0.01), homogeneous in delayed phase (13.3% vs 90.1%, p༜0.01). Conclusion To Identification of SOS and BCS should be based on the patient's laboratory examination and imaging findings to improve diagnostic accuracy.

2021 ◽  
Vol 94 (1120) ◽  
pp. 20201157
Author(s):  
Yashwant Patidar ◽  
Chandan Kumar Pal ◽  
Amar Mukund ◽  
Guresh Kumar ◽  
Shiv Kumar Sarin

Objective: Comparing the efficacy, safety and outcome of percutaneous intrervention for Budd-Chiari Syndrome (BCS) patients with bilirubin less than 3 and 3–6 mg dl−1. Methods and materials: 188 BCS patients having serum bilirubin ≤6 mg dl−1 and underwent percutaneous interventions were divided into two groups based on bilirubin level: 151 patients having bilirubin <3 mg dl−1 were included in Group 1; and 37 patients having bilirubin 3–6 mg dl−1 were included in Group 2. Both group were compare for technical success (successful recanalization of hepatic venous stenosis or creation of portocaval shunt with post-procedure gradient ≤5 mm of Hg), Safety (procedure-related mortality/morbidity or patient required transplantation) and outcome (resolution of clinical symptoms and survival). Results: Technical success was 94.7% in Group 1–89.1% in Group 2 with overall success rate was 93.6%. No significant differences observed between the two groups in regards to procedure related complication. Overall transplant-free survival at 1 and 5 years after intervention in both groups was 96.3 and 91.2% respectively. 1-year and 5-year survivals in Group 1 was 96.7%, and 93.1%, whereas Group 2 was 94.6 and 90.1% with no statically significantly difference between the two groups (p = 0.59). Percutaneous intervention results are good in patients having bilirubin up to 6 mg dl−1, i.e. mild to moderate liver dysfunctions. Conclusion: Technical success, survival and outcome of percutaneous intervention in BCS patients having serum bilirubin 3–6 mg dl−1 was comparable to patients having bilirubin level <3 mg dl−1. Advances in knowledge: Percutaneous intervention treatment is suitable for treatment for symptomatic BCS patients having bilirubin up to 6 mg  dl−1.


Author(s):  
Shyam Kumar Nandhakumar ◽  
Amirthaganesh Balasubramanium ◽  
Prabhu Sugumaran ◽  
Lokesh Kumar Thilagaraj ◽  
Armel Arputha Sivarajan

2021 ◽  
Vol 2 (3) ◽  
pp. 4-7
Author(s):  
Niveditha Dileep ◽  
John Thomas ◽  
Jisha James ◽  
Abhijith V

Background: Budd Chiari Syndrome (BCS) is the king of disorders which will mimic other disorders like chronic biliary disease, constrictive pericarditis, sinusoidal obstruction syndrome and so on, as it be like that, it is less diagnosed and treated in many countries. The prevalence of BCS is one in one million population, so it is a very rare case therefore it should be treated properly because many disorders like hematologic or malignant disease are the complications of BCS [1], [2]. Objective: To access the clinical variants of BCS along with the similarities and differences in clinical presentation, diagnostic approaches, and general treatment pattern which mimic, BCS thus gives the physician a clear outline about those disorders. Method: A man of 42 years old having BCS was taken for the study to carry out the differences in clinical features of BCS which distinguish the mimicking disorders. Clinical presentations were noted. Laboratory tests and diagnostic tests showed that the patient is having comorbidities including fatty liver with cholelithiasis, mild splenomegaly, liver parenchyma diseases, large esophageal varies with signs of recent hemorrhage, port hypertensive gastropathy and minimal ascites [3]. Patient get discharged after feeling better. Result: This patient is having chronic BCS with DIPS dysfunction. The patient had no history of liver disease before diagnosing BCS. BCS is almost curable when it is diagnosed correctly as early as possible. If not diagnosed early and treated well, comorbidities will occur, and it will affect the patient quality of life. Discussion: Early detection and proper treatment will help to control the disease up to an extent. This is depending on the physician’s knowledge. Hence, this case study clearly explains the disorders which mimic BCS for better understanding.


1993 ◽  
Vol 161 (2) ◽  
pp. 307-312 ◽  
Author(s):  
P Millener ◽  
E G Grant ◽  
S Rose ◽  
A Duerinckx ◽  
V L Schiller ◽  
...  

2021 ◽  
pp. 50-50
Author(s):  
Sangita Rathod ◽  
Shweta Pandher

Budd chiari syndrome is an uncommon disorder dened as hepatic vein outow tract obstruction, which is independent of the level and mechanism of obstruction( except pericardial disease and cardiac cirrhosis and sinusoidal obstruction syndrome)


2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Sayf Al-Katib ◽  
Robert Colvin ◽  
Farnoosh Sokhandon

Intravascular large B-cell lymphoma is a rare subtype of extranodal diffuse B-cell lymphoma characterized by proliferation of neoplastic cells within the lumen of small and medium sized vessels. Clinical and imaging findings are nebulous as the intravascular subtype of lymphoma can involve a multitude of organs. Involvement of the gallbladder is extremely uncommon, and imaging findings can be easily confused for more prevalent pathologies. We report a case of intravascular large B-cell lymphoma in an 83-year-old male and review clinical presentation and imaging findings on CT, ultrasound, hepatobiliary iminodiacetic acid (HIDA) scan, and MRI. It is important for the radiologist to know about this disease as the imaging findings are atypical of other types of lymphoma, and this may lead to a delay in diagnosis and treatment.


2007 ◽  
Vol 188 (2) ◽  
pp. W168-W176 ◽  
Author(s):  
Giuseppe Brancatelli ◽  
Valérie Vilgrain ◽  
Michael P. Federle ◽  
Antoine Hakime ◽  
Roberto Lagalla ◽  
...  

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