Renal cell carcinoma with a pelvicalyceal system tumor thrombus: a case report

Abstract Background Renal cell carcinoma (RCCs) is the most common malignancy of the kidney. When RCC progresses, it is known to form tumor thrombus in the renal vein and/or inferior vena cava. However, RCC does not normally form tumor thrombus in the pelvicalyceal system. Case presentation A 56-year-old man presented to our department for the treatment of a renal tumor with asymptomatic gross hematuria. In a dynamic CT study, contrast enhancement revealed a tumor suspected to be RCC, but atypical finding as a tumor thrombus that filled the pelvicalyceal system was also observed. Nephroureterectomy was performed, and the tumor was diagnosed histopathologically as clear cell RCC and papillary RCC. Conclusion We report a rare case of RCC directly invading the pelvicalyceal system as a thrombus mass, with no microscopic individual tumor implants in the pelvicalyceal system wall, invasion of the renal vein, or invasion of adjacent organs. To our knowledge, only six such cases have been reported in English literature, and as a result, very few theories explaining pelvicalyceal system invasion have been presented. This highlights the signiﬁcance of adding invasion of the pelvicalyceal system as part of the most recent, updated tumor metastases classiﬁcation.

Download Full-text

Single Stage Resection of Renal Cell Carcinoma with Right Atrial Extension– A Case Report

Journal of Bangladesh College of Physicians and Surgeons ◽

10.3329/jbcps.v36i2.36070 ◽

2018 ◽

Vol 36 (2) ◽

pp. 77-79

Author(s):

Syed Al Nahian ◽

Sonjoy Biswas ◽

Rezaul Hassan ◽

M Zahid Hasan

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Right Atrium ◽

Primary Tumor ◽

Renal Cell ◽

Renal Vein ◽

Tumor Thrombus ◽

Vena Cava ◽

Single Stage ◽

Right Atrial

Renal cell carcinoma (RCC) is the commonest primary tumor of the kidney which may invade through the renal vein into the inferior vena cava (IVC), and then it can extend intraluminally with subsequent tumor-thrombus formation. Here we report a case involving excision of a primary RCC with tumor-thrombus involving IVC up to right atrium with the use of extracorporeal circulation. Single stage surgical procedure was performed in collaboration with a urological team aiming complete resection of primary tumor, para-aortic lymphadenectomy and removal of IVC thrombus extending to right atrium with the help of cardiopulmonary bypass. After arresting heart, RA was opened and the mass was removed through RA from IVC and hepatic vein level. Abdominal IVC was opened and the entire residual mass was removed from below also small amount of thrombus removed from left renal vein. Postoperative venous doppler showed no residual thrombus in venous system. Histopathology report confirmed papillary renal cell carcinoma. The patient was discharged from hospital in the 12th post-operative day without any complication.J Bangladesh Coll Phys Surg 2018; 36(2): 77-79

Download Full-text

Spermatic Vein Tumor Thrombus In Renal Cell Carcinoma

The Scientific World JOURNAL ◽

10.1100/tsw.2004.67 ◽

2004 ◽

Vol 4 ◽

pp. 192-194 ◽

Cited By ~ 8

Author(s):

Nicola J. Mabjeesh ◽

Yuval Bar-Yosef ◽

Letizia Schreiber-Bramante ◽

Issac Kaver ◽

Haim Matzkin

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Renal Cell ◽

Tumor Thrombus ◽

Inferior Vena ◽

English Literature ◽

Vena Cava ◽

Spermatic Vein ◽

Renal Veins ◽

The Right

Renal cell carcinoma has the tendency to form venous thrombi. This may involve the renal veins or the inferior vena cava and may extend cephalad/antegrade into the right atrium. We report a patient with renal cell carcinoma who had an intracaval tumor thrombus that had extended into the right spermatic vein. We believe this to be the first description in English literature of a histologically proven renal cell carcinoma thrombus in the spermatic vein.

Download Full-text