scholarly journals The Analgesic Efficacy of Ultrasound-guided Transversus Abdominis Plane (TAP) Block Combined With Oral Multimodal Analgesia In Comparison With Oral Multimodal Analgesia After Caesarean Delivery: A Randomized Controlled Trial

2021 ◽  
Author(s):  
Yang Yu ◽  
Shenshan Gao ◽  
Vivian Manying Yuen ◽  
Wai Siu Choi ◽  
Xuebing Xu

Abstract Background: The transversus abdominis plane (TAP) block is used increasingly in parturients after caesarean delivery. This is a randomized controlled trial to evaluate the effectiveness of bilateral single-shot of TAP blocks in patients who received multimodal oral analgesia for postoperative pain relief.Methods: Parturients who were scheduled for elective caesarean delivery under spinal anaesthesia were recruited and randomized to receive bilateral single-shot of TAP blocks or placebo in addition to multimodal oral analgesia which consisted of regular tramadol, celecoxib and paracetamol, with oral oxycodone used as a rescue for breakthrough pain. Only parturients in the TAP group would receive the TAP blocks with an injection of 15ml (0.25%) ropivacaine on each side under aseptic techniques. All the parturients were evaluated for pain or related complications in the first 24 hours after surgery. The primary outcome is the percentage of parturients who required oxycodone as a rescue analgesia. Results: 80 and 79 parturients were allocated to the TAP and placebo group respectively. 9 out of 79 (11.4%) parturients in the TAP group and 15 out of 73 (20.5%) parturients in the placebo group required oxycodone for breakthrough pain, P = 0.122. Conclusions: Bilateral single-shot of TAP blocks confer little additional benefit when a multimodal oral analgesic regimen is used for pain control after caesarean section under spinal anaesthesia.Trial registration: Clinical Trial Registry of China (http://www.chictr.org.cn) identifier:ChiCTR-INR-16010130, retrospectively registered on Dec 12, 2016.

2020 ◽  
Author(s):  
YANG YU ◽  
Shenshan GAO ◽  
Vivian Manying YUEN ◽  
Wai Siu CHOI ◽  
Xuebing XU

Abstract Background: The transversus abdominis plane (TAP) block is used increasingly in parturients after caesarean delivery. This is a randomized controlled trial to evaluate the effectiveness of bilateral single-shot TAP blocks in patients who received multimodal oral analgesia for postoperative pain relief.Methods: Parturients who were scheduled for elective caesarean delivery under spinal anaesthesia were recruited and randomized to receive bilateral single-shot of TAP blocks or placebo in addition to multimodal oral analgesia which consisted of regular tramadol, celecoxib and paracetamol, with oral oxycodone used as rescue for breakthrough pain. Only parturients in TAP group would receive the TAP blocks with an injection of 15ml (0.25%) ropivacaine on each side under aseptic techniques. All the parturients were evaluated for pain or related complications in the first 24 hours after surgery. Primary outcome is the percentage of parturients who required oxycodone as rescue analgesia. Results: Eighty and seventy-nine parturients were allocated to TAP and placebo group respectively. Nine out of 79 (11.4%) parturients in TAP group and fifteen out of 73 (20.5%) parturients in placebo group required oxycodone for breakthrough pain, P = 0.122.Conclusions: Bilateral single-shot of TAP blocks confer little additional benefit when multimodal oral analgesic regimen is used for pain control after caesarean section under spinal anaesthesia.Trial registration:Clinical Trial Registry of China (http://www.chictr.org.cn, ChiCTR-INR-16010130). Retrospective registered on Dec 12, 2016


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yang Yu ◽  
Shenshan Gao ◽  
Vivian Man-ying Yuen ◽  
Siu-Wai Choi ◽  
Xuebing Xu

Abstract Background The transversus abdominis plane (TAP) block is used increasingly in parturients after caesarean delivery. This is a randomized controlled trial to evaluate the effectiveness of bilateral single-shot of TAP blocks in patients who received multimodal oral analgesia for postoperative pain relief. Methods Parturients who were scheduled for elective caesarean delivery under spinal anaesthesia were recruited and randomized to receive bilateral single-shot of TAP blocks or placebo in addition to multimodal oral analgesia which consisted of regular tramadol, celecoxib and paracetamol, with oral oxycodone used as a rescue for breakthrough pain. Only parturients in the TAP group would receive the TAP blocks with an injection of 15 ml (0.25%) ropivacaine on each side under aseptic techniques. All the parturients were evaluated for pain or related complications in the first 24 h after surgery. The primary outcome is the percentage of parturients who required oxycodone as a rescue analgesia. Results Eighty and 79 parturients were allocated to the TAP and placebo group respectively. Nine out of 79 (11.4%) parturients in the TAP group and 15 out of 73 (20.5%) parturients in the placebo group required oxycodone for breakthrough pain, P = 0.122. Conclusions Bilateral single-shot of TAP blocks confer little additional benefit when a multimodal oral analgesic regimen is used for pain control after caesarean section under spinal anaesthesia. Trial registration Clinical Trial Registry of China (http://www.chictr.org.cn) identifier: ChiCTR-INR-16010130, retrospectively registered on Dec 12, 2016.


2020 ◽  
Author(s):  
Yang Yu ◽  
Shenshan Gao ◽  
Vivian Manying Yuen ◽  
Wai Siu Choi ◽  
Xuebing Xu

Abstract Background: The transversus abdominis plane (TAP) block is used increasingly in parturients after caesarean delivery. This is a randomized controlled trial to evaluate the effectiveness of bilateral single-shot of TAP blocks in patients who received multimodal oral analgesia for postoperative pain relief.Methods: Parturients who were scheduled for elective caesarean delivery under spinal anaesthesia were recruited and randomized to receive bilateral single-shot of TAP blocks or placebo in addition to multimodal oral analgesia which consisted of regular tramadol, celecoxib and paracetamol, with oral oxycodone used as a rescue for breakthrough pain. Only parturients in the TAP group would receive the TAP blocks with an injection of 15ml (0.25%) ropivacaine on each side under aseptic techniques. All the parturients were evaluated for pain or related complications in the first 24 hours after surgery. The primary outcome is the percentage of parturients who required oxycodone as a rescue analgesia. Results: 80 and 79 parturients were allocated to the TAP and placebo group respectively. 9 out of 79 (11.4%) parturients in the TAP group and 15 out of 73 (20.5%) parturients in the placebo group required oxycodone for breakthrough pain, P = 0.122. Conclusions: Bilateral single-shot of TAP blocks confer little additional benefit when a multimodal oral analgesic regimen is used for pain control after caesarean section under spinal anaesthesia.Trial registration:Clinical Trial Registry of China (http://www.chictr.org.cn, ChiCTR-INR-16010130). Retrospective registered on Dec 12, 2016


2020 ◽  
Author(s):  
YANG YU ◽  
Shenshan GAO ◽  
Vivian Manying YUEN ◽  
Wai Siu CHOI ◽  
Xuebing XU

Abstract Background: The transversus abdominis plane (TAP) block is used increasing in parturients after caesarean delivery. This is a randomized controlled trial to evaluate the effectivenss of TAP in patients who received multimodal oral analgesia for postoperative pain relief.Methods: Parturient who were scheduled for elective caesarean delivery under spinal anaesthesia were recruited and randomized to receive TAP block or placebo in addition to multimodal oral analgesia which consisted of regular tramadol, celecoxib and paracetamol, with oral oxycodone used as rescue for breakthrough pain. Only parturient in TAP group would have an injection of local anaesthesia under aseptic techniques. All the parturient were evaluated for pain or related complications in the first 24 hours after surgery. Results: Eighty and 79 parturients were allocated to TAP and placebo group respectively. Nine out of 79 (11.4%) and 15 out of 73 (20.5%) parturients required oxycodone for breakthrough pain, P = 0.122. There was no difference in postoperative pain score and patient satisfactory score between the two groups. Conclusions: TAP block confers little additional benefit when multi-modal oral analgesic regimen is used for postoperative pain control after caesarean section under spinal anaesthesia.Trial registration:Clinical Trial Registry of China (http://www.chictr.org.cn, ChiCTR-INR-16010130). Retrospective registered on Dec 12, 2016


2020 ◽  
Author(s):  
Mária Földi ◽  
Alexandra Soós ◽  
Péter Hegyi ◽  
Szabolcs Kiss ◽  
Zsolt Szakács ◽  
...  

Abstract Purpose Pain after bariatric surgery can prolong recovery. This patient group is highly susceptible to opioid-related side effects. Enhanced Recovery After Surgery guidelines strongly recommend the administration of multimodal medications to reduce narcotic consumption. However, the role of ultrasound-guided transversus abdominis plane (USG-TAP) block in multimodal analgesia of weight loss surgeries remains controversial. Materials and Methods A systematic search was performed in four databases for studies published up to September 2019. We considered randomized controlled trials that assessed the efficacy of perioperative USG-TAP block as a part of multimodal analgesia in patients with laparoscopic bariatric surgery. Results Eight studies (525 patients) were included in the meta-analysis. Pooled analysis showed lower pain scores with USG-TAP block at every evaluated time point and lower opioid requirement in the USG-TAP block group (weighted mean difference (WMD) = − 7.59 mg; 95% CI − 9.86, − 5.39; p < 0.001). Time to ambulate was shorter with USG-TAP block (WMD = − 2.22 h; 95% CI − 3.89, − 0.56; p = 0.009). This intervention also seemed to be safe: only three non-severe complications with USG-TAP block were reported in the included studies. Conclusion Our results may support the incorporation of USG-TAP block into multimodal analgesia regimens of ERAS protocols for bariatric surgery.


2019 ◽  
Vol 3 (1) ◽  
pp. 52
Author(s):  
I Wayan Budi Artana ◽  
Ida Ayu Manik Damayanti

Pendahuluan: Blok pada bidang transversus abdominis (transversus abdominis plane / TAP) merupakan teknik yang dilakukan dengan injeksi lokal anestesi secara bolus dengan dosis besar tunggal pada bidang transversus abdominis. Dalam penanganan nyeri pasca operasi seksio sesarea, Transversus Abdominis Plane (TAP) block, sebagai komponen regimen analgetik multimodal, memberikan analgesia yang paling baik diantara tehnik non-opioid. Metode: Penelitian ini menggunakan rancangan penelitian Randomized Controlled Trial (RCT). Kelompok A mendapat TAP blok bilateral dengan levobupivacaine 0,5% masing-masning 15 ml, dan kelompok B (kontrol) tidak mendapat TAP blok. Hasil: Penelitian ini menunjukkan bahwa derajat nyeri pada  kelompok blok TAP lebih rendah dibanding kelompok kontrol pada jam ke-4 sampai jam ke-12 pasca operasi. Penelitian ini memperlihatkan bahwa kebutuhan fentanil total selama 24 jam pasca bedah lebih sedikit pada kelompok yang mendapatkan blok TAP (54 +  43.10 μg) dibanding kelompok kontrol (95 +  43.30 μg). Perbedaan ini bermakna secara statistik (p<0,05).Diskusi: Pada penelitian ini diketahui TAP blok dengan panduan USG sebagai komponen analgesia multimodal, memberikan analgesia yang efektif dan mengurangi kebutuhan dosis obat anelgetik pasca operasi seksio sesarea.Kata Kunci : Transversus Abdominis Plane (TAP), analgetik, operasi sesarea


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