scholarly journals Studies on the Metabolic Fate of Roxatidine Acetate Hydrochloride. (10). Blood and Plasma Concentrations, Metabolism and Excretion after a Single Intravenous Administration to Male Dogs.

1995 ◽  
Vol 10 (6) ◽  
pp. 766-778
Author(s):  
Hiroyuki OCHIAI ◽  
Kouji NAGAO ◽  
Akira FUJIKATA ◽  
Yoshihiro KAWABE ◽  
Kunio TSUKAMOTO ◽  
...  
Keyword(s):  
Intravenous Administration ◽  
Plasma Concentrations ◽  
Metabolic Fate ◽  
Roxatidine Acetate ◽  
Single Intravenous Administration ◽  
Acetate Hydrochloride

scholarly journals Metabolic Fate of NKH477. (3). Feto-Placental Transfer and Excretion into Milk in Rats after a Single Intravenous Administration.

1998 ◽  
Vol 13 (3) ◽  
pp. 229-236
Author(s):  
Tsuyoshi IRIE ◽  
Shin-ichi MATSUMOTO ◽  
Rika GODA ◽  
Toshiko EKI ◽  
Kouwa YAMASHITA
Keyword(s):  
Intravenous Administration ◽  
Placental Transfer ◽  
Metabolic Fate ◽  
Single Intravenous Administration

scholarly journals Studies on the Metabolic Fate of Loprinone Hydrochloride. (1): Blood Level, Distribution, Metabolism, Excretion after a Single Intravenous Administration to Rats.

1994 ◽  
Vol 9 (2) ◽  
pp. 149-162
Author(s):  
Kazuhiro KANEKO ◽  
Kyoichi TADANO ◽  
Kiyomi NAKAJIMA ◽  
Yoshihisa SANO ◽  
Teruaki YUZURIHA ◽  
...  
Keyword(s):  
Blood Level ◽  
Intravenous Administration ◽  
Metabolic Fate ◽  
Single Intravenous Administration

scholarly journals Penetration of Piperacillin/Tazobactam Into Gynecologic Tissues Following a Single Loading Dose Prior to Hysterectomy

1994 ◽  
Vol 2 (1) ◽  
pp. 20-24
Author(s):  
William F. O'Brien ◽  
Shelley George
Keyword(s):  
Intravenous Administration ◽  
Genital Tract ◽  
Plasma Concentrations ◽  
Female Genital Tract ◽  
Loading Dose ◽  
Effective Agent ◽  
Tissue Concentrations ◽  
Tissue Samples ◽  
Single Intravenous Administration ◽  
Female Genital

Objective:This study was undertaken to determine plasma and pelvic tissue concentrations of piperacillin/tazobactam following a single intravenous administration.Methods:Plasma and tissue samples were obtained following administration of 3 g of piperacillin and 0.375 g of tazobactam. Concentrations of these agents were determined by chromatography.Results:Plasma concentrations (mean ±SD) for piperacillin/tazobactam were 208 ± 87/27 ± 8 and 95 ± 53/14 ± 2, respectively, at 30 and 60 min after the start of the infusion. The 8:1 ratio between piperacillin and tazobactam in plasma remained constant for up to 96 min. Tissue concentrations yielded a broader range, but each agent achieved significant penetration in each of the tissues studied.Conclusions:Piperacillin/tazobactam demonstrates favorable penetration in female genital tract tissues and Should be considered a potentially effective agent for female pelvic infections.

scholarly journals Metabolic fate of KRN8601: Plasma level, distribution, metabolism and excretion of 125I-KRN8601 after a single intravenous administration to rats.

1990 ◽  
Vol 5 (3) ◽  
pp. 283-305
Author(s):  
Tadashi MISAIZU ◽  
Hiroshi SHINKAI ◽  
Hideji TANAKA ◽  
Masumi TANIMOTO ◽  
Hideaki TAKAHASHI ◽  
...  
Keyword(s):  
Plasma Level ◽  
Intravenous Administration ◽  
Metabolic Fate ◽  
Single Intravenous Administration
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