Lower Expression of HNF4α and PGC1α Might Impair Rifampicin-mediated CYP3A4 Induction under Conditions Where PXR Is Overexpressed in Human Fetal Liver Cells

2012 ◽  
Vol 27 (4) ◽  
pp. 430-438 ◽  
Author(s):  
Takashi Takezawa ◽  
Tamihide Matsunaga ◽  
Kaori Aikawa ◽  
Katsunori Nakamura ◽  
Shigeru Ohmori
Keyword(s):  
Fetal Liver ◽  
Liver Cells ◽  
Human Fetal Liver ◽  
Fetal Liver Cells ◽  
Human Fetal Liver Cells ◽  
Lower Expression ◽  
Cyp3a4 Induction

scholarly journals Comparison of Basal Gene Expression and Induction of CYP3As in HepG2 and Human Fetal Liver Cells

2007 ◽  
Vol 30 (11) ◽  
pp. 2091-2097 ◽  
Author(s):  
Masataka Maruyama ◽  
Tamihide Matsunaga ◽  
Eri Harada ◽  
Shigeru Ohmori
Keyword(s):  
Gene Expression ◽  
Fetal Liver ◽  
Liver Cells ◽  
Human Fetal Liver ◽  
Fetal Liver Cells ◽  
Human Fetal Liver Cells

scholarly journals Mechanisms of CYP3A Induction by Glucocorticoids in Human Fetal Liver Cells

2012 ◽  
Vol 27 (6) ◽  
pp. 653-657 ◽  
Author(s):  
Tamihide Matsunaga ◽  
Masataka Maruyama ◽  
Tsutomu Matsubara ◽  
Kiyoshi Nagata ◽  
Yasushi Yamazoe ◽  
...  
Keyword(s):  
Fetal Liver ◽  
Liver Cells ◽  
Human Fetal Liver ◽  
Fetal Liver Cells ◽  
Human Fetal Liver Cells

scholarly journals Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells

Hepatology ◽  
2011 ◽  
Vol 54 (6) ◽  
pp. 1901-1912 ◽  
Author(s):  
Linda Andrus ◽  
Svetlana Marukian ◽  
Christopher T. Jones ◽  
Maria Teresa Catanese ◽  
Timothy P. Sheahan ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Fetal Liver ◽  
Liver Cells ◽  
Human Fetal Liver ◽  
Fetal Liver Cells ◽  
Human Fetal Liver Cells

α-Fetoprotein production and erythropoiesis in cell cultures of human fetal liver

1977 ◽  
Vol 55 (5) ◽  
pp. 571-575 ◽  
Author(s):  
L. F. Congote ◽  
F. Bruno ◽  
S. Solomon
Keyword(s):  
Cell Function ◽  
Fetal Liver ◽  
Calf Serum ◽  
Liver Cells ◽  
Velocity Sedimentation ◽  
Erythroid Cell ◽  
Erythroid Cells ◽  
Human Fetal Liver ◽  
Fetal Liver Cells ◽  
Human Fetal Liver Cells

α-Fetoprotein and the synthesis of heme associated with hemoglobin were measured simultaneously in short-term cultures of human fetal liver cells to correlate the relationship of α-fetoprotein to erythroid cell function. Both synthetic processes decreased exponentially during the first 5 days of culture. The use of media supplemented with different batches of fetal calf serum and porcine portal vein serum indicated that the optimal conditions for the production of α-fetoprotein were different from those required for the synthesis of heme associated with hemoglobin. Moreover, the α-fetoprotein-producing cells could be separated from erythroid cells after velocity sedimentation in Ficoll gradients. Although it is well known that erythropoiesis and α-fetoprotein production occur simultaneously during ontogenesis, α-fetoprotein itself (0.01–100 μg/ml) did not stimulate heme synthesis in liver erythroid cells. Erythropoietin did not stimulate α-fetoprotein production. It is concluded that there is no cause–effect relationship between α-fetoprotein production and erythroid cell function in human fetal liver cells and that the two processes occur independently in different cell types.

Angiogenesis enhances the survival of cultured human fetal liver cells

2004 ◽  
Vol 199 (3) ◽  
pp. 97
Author(s):  
Anming Xiong ◽  
Eric Lagasse ◽  
Nobuko Uchida ◽  
Tim Austin ◽  
Stanley Tamaki ◽  
...  
Keyword(s):  
Fetal Liver ◽  
Liver Cells ◽  
Human Fetal Liver ◽  
Fetal Liver Cells ◽  
Human Fetal Liver Cells

Three-Dimensional Perfusion Bioreactor Culture Supports Differentiation of Human Fetal Liver Cells

2010 ◽  
Vol 16 (6) ◽  
pp. 2007-2016 ◽  
Author(s):  
Eva Schmelzer ◽  
Fabio Triolo ◽  
Morris E. Turner ◽  
Robert L. Thompson ◽  
Katrin Zeilinger ◽  
...  
Keyword(s):  
Fetal Liver ◽  
Three Dimensional ◽  
Liver Cells ◽  
Perfusion Bioreactor ◽  
Bioreactor Culture ◽  
Human Fetal Liver ◽  
Fetal Liver Cells ◽  
Human Fetal Liver Cells
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