scholarly journals Hyaluronic acid abrogates ethanol-dependent inhibition of collagen biosynthesis in cultured human fibroblasts

2015 ◽  
pp. 6225 ◽  
Author(s):  
Andrzej Przylipiak ◽  
Magdalena Donejko ◽  
Edyta Rysiak ◽  
Wojciech Miltyk ◽  
Elżbieta Galicka ◽  
...  
1990 ◽  
Vol 265 (3) ◽  
pp. 659-665 ◽  
Author(s):  
G A C Murrell ◽  
M J O Francis ◽  
L Bromley

The major unexplained phenomenon in fibrotic conditions is an increase in replicating fibroblasts. In this report we present evidence that oxygen free radicals can both stimulate and inhibit proliferation of cultured human fibroblasts, and that fibroblasts themselves release superoxide (O2.-) free radicals. Fibroblasts released O2.- in concentrations which stimulated proliferation, a finding confirmed by a dose-dependent inhibition of proliferation by free radical scavengers. Oxygen free radicals released by a host of agents may thus provide a very fast, specific and sensitive trigger for fibroblast proliferation. Prolonged stimulation may result in fibrosis, and agents which inhibit free radical release may have a role in the prevention of fibrosis.


1988 ◽  
Vol 263 (26) ◽  
pp. 12886-12892 ◽  
Author(s):  
H Greve ◽  
Z Cully ◽  
P Blumberg ◽  
H Kresse

1987 ◽  
Vol 262 (36) ◽  
pp. 17412-17419 ◽  
Author(s):  
W B Rizzo ◽  
D A Craft ◽  
A L Dammann ◽  
M W Phillips

1971 ◽  
Vol 42 (2) ◽  
pp. 340-345 ◽  
Author(s):  
Reuben Matalon ◽  
J.A. Cifonelli ◽  
Albert Dorfman

1980 ◽  
Vol 255 (3) ◽  
pp. 929-936 ◽  
Author(s):  
G.C. Gazzola ◽  
V. Dall'Asta ◽  
G.G. Guidotti

1974 ◽  
Vol 249 (11) ◽  
pp. 3430-3435
Author(s):  
Richard E. Hillman ◽  
Elaine F. Otto

1985 ◽  
Vol 260 (3) ◽  
pp. 1445-1451
Author(s):  
N E Owen ◽  
M L Prastein

2018 ◽  
Vol 40 ◽  
pp. 751-759 ◽  
Author(s):  
Lorenzo Cecchi ◽  
Maria Bellumori ◽  
Caterina Cipriani ◽  
Alessandra Mocali ◽  
Marzia Innocenti ◽  
...  

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