scholarly journals Abortive lytic Epstein–Barr virus replication in tonsil-B lymphocytes in infectious mononucleosis and a subset of the chronic fatigue syndrome

2012 ◽  
pp. 85 ◽  
Author(s):  
Martin Lerner ◽  
Safedin Beqaj
Biomolecules ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 185
Author(s):  
Maria Eugenia Ariza

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) or Systemic Exertion Intolerance Disease (SEID) is a chronic multisystem illness of unconfirmed etiology. There are currently no biomarkers and/or signatures available to assist in the diagnosis of the syndrome and while numerous mechanisms have been hypothesized to explain the pathology of ME/CFS, the triggers and/or drivers remain unknown. Initial studies suggested a potential role of the human herpesviruses especially Epstein-Barr virus (EBV) in the disease process but inconsistent and conflicting data led to the erroneous suggestion that these viruses had no role in the syndrome. New studies using more advanced approaches have now demonstrated that specific proteins encoded by EBV could contribute to the immune and neurological abnormalities exhibited by a subgroup of patients with ME/CFS. Elucidating the role of these herpesvirus proteins in ME/CFS may lead to the identification of specific biomarkers and the development of novel therapeutics.


Author(s):  
Leonard C. Archard ◽  
John L. Peters ◽  
Peter O. Behan ◽  
David Doyle ◽  
Michael Mackett ◽  
...  

Intervirology ◽  
1995 ◽  
Vol 38 (5) ◽  
pp. 269-273 ◽  
Author(s):  
Takeshi Sairenji ◽  
Koichi Yamanishi ◽  
Yoichi Tachibana ◽  
Giuseppe Bertoni ◽  
Takeshi Kurata

2005 ◽  
Vol 19 (2) ◽  
pp. 91-103 ◽  
Author(s):  
Ronald Glaser ◽  
David A. Padgett ◽  
Monica L. Litsky ◽  
Robert A. Baiocchi ◽  
Eric V. Yang ◽  
...  

2012 ◽  
Vol 84 (12) ◽  
pp. 1967-1974 ◽  
Author(s):  
Tessa Watt ◽  
Stephanie Oberfoell ◽  
Raymond Balise ◽  
Mitchell R. Lunn ◽  
Aroop K. Kar ◽  
...  

PEDIATRICS ◽  
2009 ◽  
Vol 124 (1) ◽  
pp. 189-193 ◽  
Author(s):  
B. Z. Katz ◽  
Y. Shiraishi ◽  
C. J. Mears ◽  
H. J. Binns ◽  
R. Taylor

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