scholarly journals VAGINAL MISOPROSTOL FOR SECOND AND THIRD TRIMESTER LABOUR INDUCTION IN WOMEN WITH INTRAUTERINE FETAL DEATH

2008 ◽  
Vol 12 (1) ◽  
pp. 43-52
Author(s):  
El-Gharib MN ◽  
Al-Ahwal LM
2010 ◽  
Vol 3 ◽  
pp. CMWH.S5797
Author(s):  
M.N. El-Gharib ◽  
M.T. El-Ebyary ◽  
T.S. Alhawary ◽  
S.H. Elshourbagy

Objectives The study was conducted to assess the effectiveness and side effects of vaginal misoprostol (Vagiprost® tablet) in termination of second and third trimester pregnancy complicated with intrauterine fetal death. Design A prospective observational cohort study. Setting Tanta University Hospital. Patients The study was carried out on 324 women with fetal demise in the second and third trimesters. Cases were collected during the period from January 2008 to December 2009. Intervention All patients were subjected to history taking, physical examination, Bishop Scoring. Application of 25 μg misoprostol in the posterior fornix of the vagina, this will be repeated every 4 hours over 24 hours. The adverse effects, progress, and outcomes were assessed. Results the success rate was 90% and 45% in women with third and second trimesters respectively. The mean induction-termination interval was 8.95 ± 2.63 and 15.3 ± 5.37 hours for women with third and second trimesters respectively. The induction termination interval correlated negatively with the duration of gestation. Approximately, 90% of second trimester and 55% of third trimester women required oxytocin augmentation. The mean value of total required dose of misoprostol was 166.3 ± 7.5 and 120 ± 28.79 μg for women with second and third trimesters respectively. Conclusion Vagiprost appears to be a safe, effective, practical, and inexpensive method for termination of third trimester pregnancy complicated with of intrauterine fetal death (IUFD), its effects increase with parity and duration of gestation.


2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Masafumi Yamamoto ◽  
Mio Takami ◽  
Ryosuke Shindo ◽  
Michi Kasai ◽  
Shigeru Aoki

Expectant management leads to successful vaginal delivery following intrauterine fetal death in a woman with an incarcerated uterus. Management of intrauterine fetal death in the second or third trimester of pregnancy in women with an incarcerated uterus is challenging. We report a case of successful vaginal delivery following intrauterine fetal death by expectant management in a woman with an incarcerated uterus. In cases of intrauterine fetal death in women with an incarcerated uterus, vaginal delivery may be possible if the incarceration is successfully reduced. If the reduction is impossible, expectant management can reduce uterine retroversion, thereby leading to spontaneous reduction of the incarcerated uterus. Thereafter, vaginal delivery may be possible.


2002 ◽  
Vol 99 (5, Part 1) ◽  
pp. 684-687
Author(s):  
Ariel Many ◽  
Ronit Elad ◽  
Yuval Yaron ◽  
Amiram Eldor ◽  
Joseph B. Lessing ◽  
...  

2014 ◽  
Vol 127 (3) ◽  
pp. 275-278 ◽  
Author(s):  
Chloé Maignien ◽  
Amélie Nguyen ◽  
Chloé Dussaux ◽  
Evelyne Cynober ◽  
Marie Gonzales ◽  
...  

2004 ◽  
Vol 191 (6) ◽  
pp. S7
Author(s):  
Ron Gonen ◽  
Noa Lavi ◽  
Dina Attias ◽  
Liliana Schliamser ◽  
Zvi Borochowitz ◽  
...  

2014 ◽  
Vol 52 (194) ◽  
pp. 785-790 ◽  
Author(s):  
Ajay Agrawal ◽  
Pritha Basnet ◽  
Achala Thakur ◽  
Pappu Rizal ◽  
Rubina Rai

Introduction: Rapid expulsion of fetus in intrauterine fetal death is usually requested without any medical grounds for it. So an efficient, safe method for induction of labor is required. The objective of this study is to determine if pre-treatment with mifepristone followed by induction of labor with misoprostol in late intrauterine fetal death is more efficacious. Methods: We conducted a randomized controlled trial in 100 patients in B.P.Koirala Institute of Health Sciences, Nepal from June 2011 to May 2013. Group A women received single oral dose of 200 mg mifepristone, followed by induction with vaginal misoprostol after 24 hours. Group B women were induced only with vaginal misoprostol. In each group, five doses of misoprostol was used four hourly. If first cycle was unsuccessful, after break of 12 hour, second course of misoprostol was started. The primary outcome was a measure of induction to delivery time and vaginal delivery within 24 hours. Secondary outcome was to measure need of oxytocin and complications. Results: Maternal age, parity and period of gestation were comparable between groups. Number of misoprostol dose needed in group A was significantly less than group B. Mann Whitney U test showed, women in group A had significantly earlier onset of labor, however total induction to delivery interval was not significant. In group A, 85.7% delivered within 24 hours of first dose of misoprostol while in group B 70% delivered within 24 hours (p=0.07). More women in Group B required oxytocin. Conclusions: Pretreatment with mifepristone before induction of labor following late intrauterine fetal death is an effective and safe regimen. It appears to shorten the duration of induction to onset of labor.  Keywords:  induction of labor; intrauterine fetal death; mifepristone; misoprostol. 


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