scholarly journals Response to the Letter to the Editor Entitled "Duloxetine-induced Hyponatremia can Occur in Not Only Syndrome of Inappropriate Secretion of Antidiuretic Hormone but Also Cerebral Salt Wasting Syndrome"

2022 ◽  
Author(s):  
Toru Hamada ◽  
Shinya Furukawa
Keyword(s):  
Antidiuretic Hormone ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Inappropriate Secretion ◽  
Letter To The Editor ◽  
Salt Wasting Syndrome

scholarly journals Central Neurogenic Diabetes Insipidus, Syndrome of Inappropriate Secretion of Antidiuretic Hormone, and Cerebral Salt-Wasting Syndrome in Traumatic Brain Injury

2012 ◽  
Vol 32 (2) ◽  
pp. e1-e7 ◽  
Author(s):  
Cynthia (Cindi) A. John ◽  
Michael W. Day
Keyword(s):  
Traumatic Brain Injury ◽  
Diabetes Insipidus ◽  
Antidiuretic Hormone ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Inappropriate Secretion ◽  
Salt Wasting Syndrome ◽  
Neurogenic Diabetes Insipidus

Central neurogenic diabetes insipidus, syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome are secondary events that affect patients with traumatic brain injury. All 3 syndromes affect both sodium and water balance; however, they have differences in pathophysiology, diagnosis, and treatment. Differentiating between hypernatremia (central neurogenic diabetes insipidus) and the 2 hyponatremia syndromes (syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome) is critical for preventing worsening neurological outcomes in patients with head injuries.

scholarly journals Cerebral Salt Wasting Syndrome (CSWS) and Potentially Fatal Neurosurgical Hyponatremia

2021 ◽  
Keyword(s):  
Antidiuretic Hormone ◽  
Study Data ◽  
University Hospital ◽  
Electrolyte Imbalance ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Cross Sectional ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Salt Wasting Syndrome

Background: Hyponatremia is considered as a common electrolyte imbalance in hospitalized patients. Cerebral salt wasting syndrome (CSWS) is an abnormality in the renal sodium transport in patients with intracranial disease, in the face of preserved thyroid and adrenal function. However, treatment of CSW and syndrome of inappropriate antidiuretic hormone (SIADH) varies, making an accurate diagnosis significant. In order to differentiate CSWS from syndrome of inappropriate antidiuretic hormone (SIADH), this study aimed to detect CSWS related hyponatremia (benign and reversible condition) in its early stages. Methods: This retrospective cross-sectional study was conducted at the Department of Neurosurgery, Ziauddin Medical University Hospital, Karachi, Pakistan from August 2016 to August 2019. All patients who had a cerebral lesion along with hyponatremia and natriuresis were included. Patients with SIADH, though considered in the differential diagnosis, were not included in the study. Data was analyzed by using SPSS (Statistical Package for the Social Sciences) and p<0.05 was considered statistically significant. Results: A total of 39 patients in a period of three years were found with CSWS-related hyponatremia, predominantly males 28(71.8%), who were operated for cranial tumors 15(38.46%). All 39(100%) had an increased uric acid level. After treatment 31(79.5%) developed post-florinef hypokalemia, while, potassium remained unaffected in 8(20.5%). Hypokalemia was noted in majority of the patients 31(79.5%) treated with fludrocortisones. Conclusion: Cerebral salt wasting syndrome was found high among males with cranial tumors. Hyponatremia in CSWS patients was found challenging if untreated might lead to mortality. However, treatment with intravenous normal saline and fludrocortisone was successful in this course. Keywords: Hyponatremia; Natriuresis; Hypovolemia; Syndrome.

scholarly journals Cerebral Salt-wasting Syndrome and Inappropriate Antidiuretic Hormone Syndrome after Subarachnoid Hemorrhaging

2017 ◽  
Vol 56 (6) ◽  
pp. 677-680 ◽  
Author(s):  
Hanako Nakajima ◽  
Hiroshi Okada ◽  
Kazuki Hirose ◽  
Toru Murakami ◽  
Yayoi Shiotsu ◽  
...  
Keyword(s):  
Antidiuretic Hormone ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Salt Wasting Syndrome

Hyponatraemia secondary to cerebral salt wasting syndrome following routine pituitary surgery

1996 ◽  
Vol 135 (2) ◽  
pp. 245-247 ◽  
Author(s):  
Stephen L Atkin ◽  
Anne Marie Coady ◽  
Michael C White ◽  
Bruce Mathew
Keyword(s):  
Antidiuretic Hormone ◽  
Transsphenoidal Surgery ◽  
Venous Pressure ◽  
Hormone Secretion ◽  
Pituitary Surgery ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Salt Wasting Syndrome

Atkin SL, Coady AM. White MC, Mathew B. Hyponatraemia secondary to cerebral salt wasting syndrome following routine pituitary surgery. Eur J Endocrinol 1996;135:245–7. ISSN 0804–4643 A female aged 53 years was found to have a suprasellar lesion, which was shown to be a Rathke's cyst after removal by transsphenoidal surgery. She presented 16 days postoperatively, and following two grand mal seizures was found to be profoundly hyponatraemic (sodium 101 mmol/l). She was initially thought to have the syndrome of inappropriate antidiuretic hormone and was treated accordingly, but central venous pressure measurement revealed the hypovolaemia of cerebral salt wasting syndrome. The patient subsequently developed severe neurological sequelae after the correction of her hyponatraemia, following the development of extrapontine myelinolysis. Cerebral salt wasting syndrome is a rare cause of hyponatraemia following pituitary transsphenoidal surgery, which may mimic the syndrome of inappropriate antidiuretic hormone secretion. This case emphasizes the poor prognosis that may result from the rapid correction of profound hyponatraemia. SL Atkin, Michael White Centre for Diabetes and Endocrinology, Royal Hull Hospitals, 220-236 Anlaby Road, Hull HU3 2RW, UK

scholarly journals Early hyponatraemia after pituitary surgery: cerebral salt-wasting syndrome

2007 ◽  
Vol 156 (6) ◽  
pp. 611-616 ◽  
Author(s):  
R Guerrero ◽  
A Pumar ◽  
A Soto ◽  
M A Pomares ◽  
S Palma ◽  
...  
Keyword(s):  
Specific Treatment ◽  
Pituitary Surgery ◽  
Pituitary Tumour ◽  
Common Complication ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Inappropriate Secretion ◽  
Salt Wasting Syndrome

Hyponatraemia is a common complication in patients undergoing neurosurgery. It can be caused either by the syndrome of inappropriate secretion of antidiuretic hormone or by the cerebral salt-wasting syndrome (CSWS). CSWS frequently occurs in patients suffering from subarachnoid haemorrhage and brain injury, but it is rare after pituitary tumour surgery. However, this diagnostic possibility should be considered as these disorders require specific treatment and have different prognoses. In this article, we present a case of acute and early hyponatraemia caused by CSWS after pituitary tumour surgery. We also revise the aetiology, mechanisms, differential diagnosis and treatment of hyponatraemia after pituitary surgery.

Sign in / Sign up

Export Citation Format

Share Document