scholarly journals Central Neurogenic Diabetes Insipidus, Syndrome of Inappropriate Secretion of Antidiuretic Hormone, and Cerebral Salt-Wasting Syndrome in Traumatic Brain Injury

2012 ◽  
Vol 32 (2) ◽  
pp. e1-e7 ◽  
Author(s):  
Cynthia (Cindi) A. John ◽  
Michael W. Day

Central neurogenic diabetes insipidus, syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome are secondary events that affect patients with traumatic brain injury. All 3 syndromes affect both sodium and water balance; however, they have differences in pathophysiology, diagnosis, and treatment. Differentiating between hypernatremia (central neurogenic diabetes insipidus) and the 2 hyponatremia syndromes (syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome) is critical for preventing worsening neurological outcomes in patients with head injuries.

1992 ◽  
Vol 115 (3-4) ◽  
pp. 156-162 ◽  
Author(s):  
T. Yamaki ◽  
A. Tano-oka ◽  
A. Takahashi ◽  
T. Imaizumi ◽  
K. Suetake ◽  
...  

2017 ◽  
Author(s):  
Maria Manuel Costa ◽  
Cesar Esteves ◽  
Jose Luis Castedo ◽  
Josue Pereira ◽  
Davide Carvalho

2009 ◽  
Vol 40 (2) ◽  
pp. 84-87 ◽  
Author(s):  
Jainn-Jim Lin ◽  
Kuang-Lin Lin ◽  
Shao-Hsuan Hsia ◽  
Chang-Teng Wu ◽  
Huei-Shyong Wang

2011 ◽  
Vol 153 (8) ◽  
pp. 1719-1720 ◽  
Author(s):  
M. Kontogiorgi ◽  
P. Opsimoulis ◽  
E. Diamanti-Kandarakis ◽  
A. Karabinis

Author(s):  
Mohamed Aziz Daghmouri ◽  
Maroua Oueslati ◽  
Mohamed Amine Touati ◽  
Olfa Faten ◽  
Sameh Zakhama ◽  
...  

Following acute traumatic brain injury, cerebral salt wasting (CSW) syndrome is considered as an important cause of hyponatremia apart from syndrome of inappropriate antidiuretic hormone. Differentiation between the two syndromes is crucial for the initiation of an adequate treatment. So we report a pediatric case.


2021 ◽  
Vol 10 (3) ◽  
pp. 182-192
Author(s):  
Dhania A. Santosa ◽  
◽  
Nancy Margareta Rehatta

Electrolyte imbalance is an often incident in patients underwent neurosurgery and it potentially induces secondary brain injury, leading to a worse outcome, despite successful surgery. Diabetes insipidus is a frequent hypernatremic condition, commonly caused by abnormalities in the hypophysis; but rarely happens due to pineal tumor. A 21-year-old male with preoperative diabetes insipidus experienced episodes of diabetes insipidus complicated by cerebral salt wasting syndrome and tension pneumocephalus after a successful pineal tumor removal surgery. Closed observation on volume status, plasma glucose and electrolyte, along with optimal dose of desmopressin were keys of successful postoperative management in this patient in order to avoid the patient from secondary brain injury. An intensivist plays a key role, mainly in the understanding of intracranial pathophysiology and its implications to fluid and electrolyte balance.


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