Role of NT-ProBNP to differentiate syndrome of inappropriate antidiuretic hormone secretion and cerebral salt wasting syndrome: The conundrum

2018 ◽  
Vol 66 (5) ◽  
pp. 1389
Author(s):  
Pinaki Dutta ◽  
Rimesh Pal ◽  
Ashutosh Rai ◽  
Sivashanmugam Dhandapani
Keyword(s):  
Antidiuretic Hormone ◽  
Hormone Secretion ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Inappropriate Antidiuretic Hormone Secretion ◽  
Salt Wasting ◽  
Antidiuretic Hormone Secretion ◽  
Wasting Syndrome ◽  
Salt Wasting Syndrome

Hyponatraemia secondary to cerebral salt wasting syndrome following routine pituitary surgery

1996 ◽  
Vol 135 (2) ◽  
pp. 245-247 ◽  
Author(s):  
Stephen L Atkin ◽  
Anne Marie Coady ◽  
Michael C White ◽  
Bruce Mathew
Keyword(s):  
Antidiuretic Hormone ◽  
Transsphenoidal Surgery ◽  
Venous Pressure ◽  
Hormone Secretion ◽  
Pituitary Surgery ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Salt Wasting Syndrome

Atkin SL, Coady AM. White MC, Mathew B. Hyponatraemia secondary to cerebral salt wasting syndrome following routine pituitary surgery. Eur J Endocrinol 1996;135:245–7. ISSN 0804–4643 A female aged 53 years was found to have a suprasellar lesion, which was shown to be a Rathke's cyst after removal by transsphenoidal surgery. She presented 16 days postoperatively, and following two grand mal seizures was found to be profoundly hyponatraemic (sodium 101 mmol/l). She was initially thought to have the syndrome of inappropriate antidiuretic hormone and was treated accordingly, but central venous pressure measurement revealed the hypovolaemia of cerebral salt wasting syndrome. The patient subsequently developed severe neurological sequelae after the correction of her hyponatraemia, following the development of extrapontine myelinolysis. Cerebral salt wasting syndrome is a rare cause of hyponatraemia following pituitary transsphenoidal surgery, which may mimic the syndrome of inappropriate antidiuretic hormone secretion. This case emphasizes the poor prognosis that may result from the rapid correction of profound hyponatraemia. SL Atkin, Michael White Centre for Diabetes and Endocrinology, Royal Hull Hospitals, 220-236 Anlaby Road, Hull HU3 2RW, UK

scholarly journals Central Neurogenic Diabetes Insipidus, Syndrome of Inappropriate Secretion of Antidiuretic Hormone, and Cerebral Salt-Wasting Syndrome in Traumatic Brain Injury

2012 ◽  
Vol 32 (2) ◽  
pp. e1-e7 ◽  
Author(s):  
Cynthia (Cindi) A. John ◽  
Michael W. Day
Keyword(s):  
Traumatic Brain Injury ◽  
Diabetes Insipidus ◽  
Antidiuretic Hormone ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Inappropriate Secretion ◽  
Salt Wasting Syndrome ◽  
Neurogenic Diabetes Insipidus

Central neurogenic diabetes insipidus, syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome are secondary events that affect patients with traumatic brain injury. All 3 syndromes affect both sodium and water balance; however, they have differences in pathophysiology, diagnosis, and treatment. Differentiating between hypernatremia (central neurogenic diabetes insipidus) and the 2 hyponatremia syndromes (syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome) is critical for preventing worsening neurological outcomes in patients with head injuries.

Cerebral salt wasting syndrome distinct from the syndrome of inappropriate secretion of antidiuretic hormone (SIADH)

1992 ◽  
Vol 115 (3-4) ◽  
pp. 156-162 ◽  
Author(s):  
T. Yamaki ◽  
A. Tano-oka ◽  
A. Takahashi ◽  
T. Imaizumi ◽  
K. Suetake ◽  
...  
Keyword(s):  
Antidiuretic Hormone ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Inappropriate Secretion ◽  
Salt Wasting Syndrome

scholarly journals Syndrome of inappropriate antidiuretic hormone secretion and cerebral salt wasting as the common causes of hyponatremia in tertiary care hospital

2020 ◽  
Vol 7 (4) ◽  
pp. 577
Author(s):  
Yogesh Pralhad Bade ◽  
Harishchandra Rameshchandra Chaudhari
Keyword(s):  
Antidiuretic Hormone ◽  
Tertiary Care ◽  
Hormone Secretion ◽  
Cerebral Salt Wasting ◽  
Common Cause ◽  
Inappropriate Antidiuretic Hormone Secretion ◽  
Salt Wasting ◽  
Antidiuretic Hormone Secretion ◽  
Common Causes ◽  
The Common

Background: Hyponatremia is a typical condition of electrolyte disturbance that may be euvolemic, hypovolemic or hypervolemic. Proper interpretation through laboratory tests helps to differentiate the types and causes of hyponatremia. This study was conducted to evaluate the syndrome of inappropriate antidiuretic hormone secretion (SIADH) and cerebral salt wasting (CSW) as the common causes of hyponatremia in tertiary care hospital.Methods: A prospective interventional study was conducted, including hyponatremia cases, admitted in NTU/ICU/CCU and other medical wards at Ruby Hall Clinic from August 2011 to December 2013.Results: Of 150 patients enrolled in this study, 33.33% patients were euvolemic, 34% patients were hypervolemic and 32.66% patients were hypovolemic. For the euvolemic patients, SIADH (68%) was the most common cause; whereas, CSW (34.39%) was the common cause for hypovolemic type of hyponatremia. Stroke was found to be the most common cause of SIADH (55.88%), Intra-cerebral bleeding was observed to be the most common causative factor between SIADH and CSW associated hyponatremia.Conclusions: Hyponatremia in central nervous system disorder patients frequently occurred due to SIADH and CSW. Most common cause of SIADH was stroke and for CSW it was intra cerebral bleed.

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