Targeting the Alpha 7 Nicotinic Acetylcholine Receptor to Reduce Amyloid Accumulation in Alzheimers Disease Pyramidal Neurons

Current Pharmaceutical Design ◽

10.2174/138161206775474224 ◽

2006 ◽

Vol 12 (6) ◽

pp. 677-684 ◽

Author(s):

Michael D'Andrea ◽

Robert Nagele

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Pyramidal Neurons ◽

Alzheimers Disease ◽

Nicotinic Acetylcholine ◽

Amyloid Accumulation ◽

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Reduced Size and Macrophage Content of Advanced Atherosclerotic Lesions in Mice with Bone Marrow Specific Deficiency of Alpha 7 Nicotinic Acetylcholine Receptor

PLoS ONE ◽

10.1371/journal.pone.0124584 ◽

2015 ◽

Vol 10 (3) ◽

pp. e0124584 ◽

Author(s):

Robert H. Lee ◽

Guillermo Vazquez

Keyword(s):

Bone Marrow ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Atherosclerotic Lesions ◽

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P4-310: Preclinical characterization of a selective alpha-7 neuronal nicotinic acetylcholine receptor agonist ABT-126: A novel therapeutic agent for the treatment of cognitive impairment in Alzheimer's disease and schizophrenia

Alzheimer s & Dementia ◽

10.1016/j.jalz.2013.05.1755 ◽

2013 ◽

Vol 9 ◽

pp. P817-P818 ◽

Author(s):

Robert Bitner ◽

David Anderson ◽

Karla Drescher ◽

Kathy Kohlhaas ◽

Halvard Gronlien ◽

...

Keyword(s):

Cognitive Impairment ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Therapeutic Agent ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Alpha 7 ◽

Novel Therapeutic

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Chronic Nicotine Inhalation‐Induced Vascular Dysfunction is Mediated by the Alpha 7 Nicotinic Acetylcholine Receptor

The FASEB Journal ◽

10.1096/fasebj.2021.35.s1.02657 ◽

2021 ◽

Vol 35 (S1) ◽

Author(s):

Anna Whitehead ◽

Nicholas Fried ◽

Tamara Morris ◽

Charlotte Pearson ◽

Zhen Li ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Vascular Dysfunction ◽

Nicotinic Acetylcholine ◽

Chronic Nicotine ◽

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S59. Alpha-7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator Galantamine in Autism Spectrum Disorder

Biological Psychiatry ◽

10.1016/j.biopsych.2018.02.950 ◽

2018 ◽

Vol 83 (9) ◽

pp. S369-S370

Author(s):

Asif Rahman ◽

Robert Freedman ◽

Eric Hollander

Keyword(s):

Autism Spectrum Disorder ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Autism Spectrum ◽

Spectrum Disorder ◽

Allosteric Modulator ◽

Positive Allosteric Modulator ◽

Nicotinic Acetylcholine ◽

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The Alpha 7 Nicotinic Acetylcholine Receptor

Bursting Neurons and Fading Memories ◽

10.1016/b978-0-12-801979-5.00011-4 ◽

2015 ◽

pp. 95-98

Author(s):

Michael R. D’Andrea

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

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Abstract 1394: Beta-cryptoxanthin suppresses cancer cell motility and angiogenesis via inhibiting alpha 7-nicotinic acetylcholine receptor-mediated PI3K pathway

10.1158/1538-7445.am2011-1394 ◽

2011 ◽

Author(s):

Benchun Miao ◽

Xiang-Dong Wang

Keyword(s):

Cell Motility ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Cancer Cell ◽

Pi3k Pathway ◽

Nicotinic Acetylcholine ◽

Cancer Cell Motility ◽

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P.689 Cognitive enhancers in schizophrenia: A meta-analysis of Alpha-7 nicotinic acetylcholine receptor agonists for cognitive deficits and negative symptoms

European Neuropsychopharmacology ◽

10.1016/j.euroneuro.2019.09.657 ◽

2019 ◽

Vol 29 ◽

pp. S465-S466

Author(s):

M. Recio-Barbero ◽

A. Zabala ◽

R. Segarra ◽

B. Santos ◽

F.J. Ballesteros

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Cognitive Deficits ◽

Negative Symptoms ◽

Meta Analysis ◽

Nicotinic Acetylcholine ◽

Cognitive Enhancers ◽

Receptor Agonists ◽

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The roles of nicotinic acetylcholine receptor alpha 7 in mediating effects of smoking in lung cancer

10.5353/th_991043982884003414 ◽

2017 ◽

Author(s):

Ziyu Ning

Keyword(s):

Lung Cancer ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Mediating Effects ◽

Nicotinic Acetylcholine ◽

Receptor Alpha ◽

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Insights from modelling the 3D structure of the extracellular domain of $alpha;7 nicotinic acetylcholine receptor*1

Biochemical and Biophysical Research Communications ◽

10.1016/s0006-291x(04)00968-4 ◽

2004 ◽

Author(s):

K CHOU

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

3D Structure ◽

Extracellular Domain ◽

Nicotinic Acetylcholine ◽

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AB0138 Mice lacking the alpha 7 nicotinic acetylcholine receptor have increased bone mass

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2012-eular.138 ◽

2013 ◽

Vol 71 (Suppl 3) ◽

pp. 645.11-645

Author(s):

P. Mandl ◽

S. Hayer ◽

S. Huck ◽

B. Niederreiter ◽

P. Scholze ◽

...

Keyword(s):

Bone Mass ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

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