Effect of Local Paclitaxel Delivery Following Stenting on Restenosis and Morphology in the Porcine Coronary Artery

2008 ◽  
Vol 2 (1) ◽  
pp. 299-303
Author(s):  
Martin Oberhoff ◽  
Matthias Lerch ◽  
Christian Herdeg ◽  
Axel Kuttner ◽  
Stephen Schroder ◽  
...  
1992 ◽  
Vol 67 (05) ◽  
pp. 582-584 ◽  
Author(s):  
Ichiro Miki ◽  
Akio Ishii

SummaryWe characterized the thromboxane A2/prostaglandin H2 receptors in porcine coronary artery. The binding of [3H]SQ 29,548, a thromboxane A2 antagonist, to coronary arterial membranes was saturable and displaceable. Scatchard analysis of equilibrium binding showed a single class of high affinity binding sites with a dissociation constant of 18.5 ±1.0 nM and the maximum binding of 80.7 ± 5.2 fmol/mg protein. [3H]SQ 29,548 binding was concentration-dependently inhibited by thromboxane A2 antagonists such as SQ 29,548, BM13505 and BM13177 or the thromboxane A2 agonists such as U46619 and U44069. KW-3635, a novel dibenzoxepin derivative, concentration-dependently inhibited the [3H]SQ 29,548 binding to thromboxane A2/prosta-glandin H2 receptors in coronary artery with an inhibition constant of 6.0 ± 0.69 nM (mean ± S.E.M.).


2000 ◽  
Vol 27 (9) ◽  
pp. 680-683
Author(s):  
Tetsuya Sasaki ◽  
Michio Hashimoto ◽  
Seishi Nosaka ◽  
Tomoki Hanada ◽  
Yuhei Saitoh ◽  
...  

2012 ◽  
Vol 59 (13) ◽  
pp. E315
Author(s):  
Takeshi Ijichi ◽  
Gaku Nakazawa ◽  
Toshiro Shinke ◽  
Daisuke Matsumoto ◽  
Hiromasa Otake ◽  
...  

1987 ◽  
Vol 64 (1) ◽  
pp. 21-25 ◽  
Author(s):  
J.M. Davies ◽  
S.E. Epstein ◽  
J.E. Pierce ◽  
P.W. Ramwell ◽  
D. Sprecher

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