In Vivo Assessment of Cytochrome P450 3A4 and P-Glycoprotein Activity:Impact on Clinical Practice

Current Enzyme Inhibition ◽

10.2174/157340807781369065 ◽

2007 ◽

Vol 3 (3) ◽

pp. 217-241 ◽

Author(s):

Wim Lemahieu ◽

Bart Maes

Keyword(s):

Cytochrome P450 ◽

Clinical Practice ◽

Cytochrome P450 3A4 ◽

P Glycoprotein ◽

In Vivo Assessment

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P-glycoprotein and cytochrome P450 3A4 involvement in risperidone transport using an in vitro Caco-2/TC7 model and an in vivo model

Progress in Neuro-Psychopharmacology and Biological Psychiatry ◽

10.1016/j.pnpbp.2007.01.028 ◽

2007 ◽

Vol 31 (4) ◽

pp. 878-886 ◽

Author(s):

Etienne Cousein ◽

Christine Barthélémy ◽

Stéphanie Poullain ◽

Nicolas Simon ◽

Sophie Lestavel ◽

...

Keyword(s):

Cytochrome P450 ◽

In Vivo Model ◽

Cytochrome P450 3A4 ◽

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Pharmacogenetics of Clozapine: In Vivo Role of Cytochrome P450 Isoforms and P-Glycoprotein

Pharmacopsychiatry ◽

10.1055/s-0028-1088256 ◽

2008 ◽

Vol 41 (05) ◽

Author(s):

E Jaquenoud-Sirot ◽

B Knezevic ◽

G Perla Morena ◽

P Baumann ◽

CB Eap

Keyword(s):

Cytochrome P450 ◽

P Glycoprotein ◽

Cytochrome P450 Isoforms

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Effects of myricetin, an antioxidant, on the pharmacokinetics of losartan and its active metabolite, EXP-3174, in rats: possible role of cytochrome P450 3A4, cytochrome P450 2C9 and P-glycoprotein inhibition by myricetin

Journal of Pharmacy and Pharmacology ◽

10.1211/jpp.62.07.0012 ◽

2010 ◽

Vol 62 (7) ◽

pp. 908-914 ◽

Author(s):

Dong-Hyun Choi ◽

Cheng Li ◽

Jun-Shik Choi

Keyword(s):

Cytochrome P450 ◽

Active Metabolite ◽

Cytochrome P450 3A4 ◽

Cytochrome P450 2C9 ◽

P Glycoprotein ◽

Glycoprotein Inhibition

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Simultaneous determination of dexamethasone and 6β-hydroxydexamethasone in urine using solid-phase extraction and liquid chromatography: applications to in vivo measurement of cytochrome P450 3A4 activity

Journal of Chromatography B ◽

10.1016/j.jchromb.2004.01.053 ◽

2004 ◽

Vol 804 (2) ◽

pp. 421-429 ◽

Author(s):

K Zurbonsen ◽

F Bressolle ◽

I Solassol ◽

P.J Aragon ◽

S Culine ◽

...

Keyword(s):

Cytochrome P450 ◽

Liquid Chromatography ◽

Solid Phase Extraction ◽

Simultaneous Determination ◽

Solid Phase ◽

Cytochrome P450 3A4 ◽

Phase Extraction ◽

In Vivo Measurement

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Cytochrome P450 3A4 and P-glycoprotein mediate the interaction between an oral erythromycin breath test and rifampin

Clinical Pharmacology & Therapeutics ◽

10.1067/mcp.2002.128387 ◽

2002 ◽

Vol 72 (5) ◽

pp. 524-535 ◽

Author(s):

M Paine

Keyword(s):

Cytochrome P450 ◽

Breath Test ◽

Cytochrome P450 3A4 ◽

P Glycoprotein ◽

Erythromycin Breath Test

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Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: a comparative analysis in paired tissue specimens

Clinical Pharmacology & Therapeutics ◽

10.1016/j.clpt.2003.10.008 ◽

2004 ◽

Vol 75 (3) ◽

pp. 172-183 ◽

Author(s):

O VONRICHTER ◽

O BURK ◽

M FROMM ◽

K THON ◽

M EICHELBAUM ◽

...

Keyword(s):

Cytochrome P450 ◽

Comparative Analysis ◽

Cytochrome P450 3A4 ◽

P Glycoprotein ◽

Small Intestinal ◽

Tissue Specimens ◽

Intestinal Enterocytes

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In vitro and in vivo assessment of cytochrome P450-mediated herb–drug interaction of Ssang-hwa-tang

Food Chemistry ◽

10.1016/j.foodchem.2012.08.069 ◽

2013 ◽

Vol 136 (2) ◽

pp. 450-457 ◽

Author(s):

Sang Yoon Lee ◽

Ji-Yoon Lee ◽

Wonku Kang ◽

Kwang-il Kwon ◽

Soo Jin Oh ◽

...

Keyword(s):

Cytochrome P450 ◽

Drug Interaction ◽

In Vivo Assessment

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Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4–dependent pharmacokinetics in humans

Clinical Pharmacology & Therapeutics ◽

10.1016/j.clpt.2006.01.005 ◽

2006 ◽

Vol 79 (5) ◽

pp. 449-460 ◽

Author(s):

L BECQUEMONT ◽

H GLAESER ◽

S DRESCHER ◽

M HITZL ◽

N SIMON ◽

...

Keyword(s):

Cytochrome P450 ◽

Ursodeoxycholic Acid ◽

Cytochrome P450 3A4 ◽

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Investigation of the Coordinated Functional Activities of Cytochrome P450 3A4 and P‐Glycoprotein in Limiting the Absorption of Xenobiotics in Caco‐2 Cells

Journal of Pharmaceutical Sciences ◽

10.1002/jps.1173 ◽

2002 ◽

Vol 91 (1) ◽

pp. 117-128 ◽

Author(s):

Christine D.H. Tran ◽

Peter Timmins ◽

Barbara R. Conway ◽

William J. Irwin

Keyword(s):

Cytochrome P450 ◽

Cytochrome P450 3A4 ◽

Functional Activities ◽

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The Interaction of Selected Phytochemicals, HIV Drugs, and Commercial-Source Herbal Teas and Capsules with Human Cytochrome P450 3A4 and P-glycoprotein

Pharmaceutical Biology ◽

10.1080/13880200701729844 ◽

2008 ◽

Vol 46 (1-2) ◽

pp. 53-65 ◽

Author(s):

Jason W. Budzinski ◽

Brian C. Foster ◽

Vance L. Trudeau ◽

Cathy E. Drouin ◽

Nana Bafi-Yeboa ◽

...

Keyword(s):

Cytochrome P450 ◽

Cytochrome P450 3A4 ◽

P Glycoprotein ◽

Human Cytochrome ◽

Commercial Source ◽

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