Voltammetry Determination of Cefotaxime on Zinc Oxide Nanorod Modified Electrode

Background: The Glassy Carbon Electrode (GCE) was modified with zinc oxide nanoparticles to enhance the electrocatalytic activity of the redox behavior of cefotaxime ion. ATOMIC Force Microscopy (AFM) photographic studies showed the nanorod like structure of the zinc oxide, which was coated uniformly on the electrode surface. Methods: The zinc oxide nanorod modified electrode was used as novel voltammetric determination of cefotaxime. The results of voltammetric behavior are satisfactory in the electro oxidation of cefotaxime, and exhibit considerable improvement compared to glassy carbon electrode. Results: Under the optimized experimental conditions, the ZnO nanorod modified electrode exhibit better linear dynamic range from 300 ppb to 700 ppb with lower limit of detection 200 ppb for the stripping voltammetric determination of cefotaxime. Conclusion: The pharmaceutical and clinical formulation of cefotaxime was successfully applied for accurate determination of trace amounts on ZnO nanomateials modified electrode.

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Electrocatalytic Response and Determination of Noradrenaline in the Presence of L-Ascorbic and Uric Acids with Poly(Eriochrome Black T)-Modified Electrode

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc20071177 ◽

2007 ◽

Vol 72 (9) ◽

pp. 1177-1188 ◽

Cited By ~ 7

Author(s):

Xinhua Lin ◽

Wei Li ◽

Hong Yao ◽

Yuanyuan Sun ◽

Liying Huang ◽

...

Keyword(s):

Glassy Carbon Electrode ◽

Modified Electrode ◽

Glassy Carbon ◽

Dynamic Range ◽

Differential Pulse ◽

Carbon Electrode ◽

Modified Glassy Carbon Electrode ◽

Eriochrome Black T ◽

Wide Linear Dynamic Range

A poly(Eriochrome Black T) chemically modified glassy carbon electrode modified with Eriochrome Black T was prepared by cyclic voltammetry. The modified electrode showed an excellent electrocatalytic activity in oxidation of noradrenaline (NA) and could separate its electrochemical responses from those of L-ascorbic acid (AA) and uric acid (UA). Differences of the oxidation peak potentials for NA-AA and UA-NA were about 150 mV. The responses to NA, AA and UA of the modified electrode are relatively independent. Using differential pulse voltammetry, the peak currents of NA at modified glassy carbon electrode increased linearly with the concentration of NA from 0.5 to 100 μmol l-1. The detection limit was 0.2 μmol l-1. With the modified electrode, UA could be selectively determined in the presence of AA. The method showing a wide linear dynamic range and excellent sensitivity was successfully applied to the determination of NA in pharmaceutical injections and various samples.

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Preparation and Application of Keggin Silicomolybdic acid Modified Electrode

10.21203/rs.2.24140/v1 ◽

2020 ◽

Author(s):

Miao Liu ◽

Mingxuan Jia ◽

Dong Hui Li

Keyword(s):

Glassy Carbon Electrode ◽

Modified Electrode ◽

Glassy Carbon ◽

Photoelectron Spectroscopy ◽

Limit Of Detection ◽

Differential Pulse ◽

Carbon Electrode ◽

X Ray ◽

Linear Relationships

Abstract An innovative method for the determination of isoniazid tablets is studied through electrochemical method for the modification of glassy carbon electrode (GCE). Polyoxomolybdate, with stable structures, has not been widely used for the determination of substance. In this study, the mentioned polyoxomolybdate was characterized by Fourier transform infrared spectroscopy (FT-IR), UV-vis, X-ray diffraction (XRD), Atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS), and used to modify the glassy carbon electrode. The electrochemical performance of the polyoxomolybdate@GCE was investigated with cyclic voltammetry (CV) and differential pulse voltammetry (DPV), compared with the unmodified electrode, the proposed polyoxomolybdate modified electrode exhibited strong electro-catalytic activities towards isoniazid (INH). Under the optimized conditions, there was linear relationships between the DPV peak currents and the concentrations in the range of 1 × 10 -7 g/L to 3 × 10 -7 g/L for INH (R 2 = 0.9979), with the limit of detection (LOD) of 0.024 μg/L (based on S/N = 3). The modified electrode has proper reproducibility (RSD < 5%), stability, response time (< 3 min) and lifetime (up to 6 days).

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Voltammetric determination of ascorbic acid with zinc oxide modified glassy carbon electrode

Journal of the Iranian Chemical Society ◽

10.1007/s13738-019-01668-5 ◽

2019 ◽

Vol 16 (9) ◽

pp. 1957-1963 ◽

Cited By ~ 1

Author(s):

Nadia Ait Ahmed ◽

Houa Hammache ◽

Marielle Eyraud ◽

Carine Chassigneux ◽

Florence Vacandio ◽

...

Keyword(s):

Ascorbic Acid ◽

Zinc Oxide ◽

Glassy Carbon Electrode ◽

Glassy Carbon ◽

Voltammetric Determination ◽

Carbon Electrode ◽

Modified Glassy Carbon Electrode

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Preparation and Application of Keggin Silicomolybdic acid Modified Electrode

10.21203/rs.2.22798/v1 ◽

2020 ◽

Author(s):

Miao Liu ◽

Dong hui Li ◽

Ming xuan Jia

Keyword(s):

Glassy Carbon Electrode ◽

Modified Electrode ◽

Glassy Carbon ◽

Photoelectron Spectroscopy ◽

Limit Of Detection ◽

Differential Pulse ◽

Carbon Electrode ◽

X Ray ◽

Linear Relationships

Abstract An innovative method for the determination of isoniazid tablets is studied through electrochemical method for the modification of glassy carbon electrode (GCE). Polyoxomolybdate, with stable structures, has not been widely used for the determination of substance. In this study, the mentioned polyoxomolybdate was characterized by Fourier transform infrared spectroscopy (FT-IR), UV-vis, X-ray diffraction (XRD), Atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS), and used to modify the glassy carbon electrode (GCE). The electrochemical performance of the polyoxomolybdate@GCE was investigated with cyclic voltammetry (CV) and differential pulse voltammetry (DPV), compared with the unmodified electrode, the proposed polyoxomolybdate modified electrode exhibited strong electro-catalytic activities towards isoniazid (INH). Under the optimized conditions, there was linear relationships between the DPV peak currents and the concentrations in the range of 1 × 10 -7 g/L to 3 × 10 -7 g/L for INH (R 2 = 0.9979), with the limit of detection (LOD) of 0.024 μg/L (based on S/N = 3). The modified electrode has proper reproducibility (RSD < 5%), stability, response time (< 3 min) and lifetime (up to 6 days).

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Sensitive Voltammetric Determination of Bisphenol A Based on a Glassy Carbon Electrode Modified with Copper Oxide-Zinc Oxide Decorated on Graphene Oxide

Electroanalysis ◽

10.1002/elan.201800415 ◽

2018 ◽

Vol 31 (1) ◽

pp. 91-102 ◽

Cited By ~ 9

Author(s):

Şükriye Ulubay Karabiberoğlu

Keyword(s):

Zinc Oxide ◽

Graphene Oxide ◽

Bisphenol A ◽

Copper Oxide ◽

Glassy Carbon Electrode ◽

Glassy Carbon ◽

Voltammetric Determination ◽

Carbon Electrode

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Improved Voltammetric Determination of Kynurenine at the Nafion Covered Glassy Carbon Electrode – Application in Samples Delivered from Human Cancer Cells

International Journal of Tryptophan Research ◽

10.1177/11786469211023468 ◽

2021 ◽

Vol 14 ◽

pp. 117864692110234

Author(s):

Ilona Sadok ◽

Katarzyna Tyszczuk-Rotko ◽

Robert Mroczka ◽

Jędrzej Kozak ◽

Magdalena Staniszewska

Keyword(s):

Glassy Carbon Electrode ◽

Glassy Carbon ◽

Limit Of Detection ◽

Accurate Determination ◽

Differential Pulse ◽

Carbon Electrode ◽

Reliable Determination ◽

Accumulation Time ◽

Cell Extracts

Nowadays, development of analytical methods responding to a need for rapid and accurate determination of human metabolites is highly desirable. Herein, an electrochemical method employing a Nafion-coated glassy carbon electrode (Nafion/GCE) has been developed for reliable determination of kynurenine (a key tryptophan metabolite) using a differential pulse adsorptive stripping voltammetry. To our knowledge, this is the first analytical method to allow for kynurenine determination at the Nafion-coated electrode. The methodology involves kynurenine pre-concentration in 0.1 M H2SO4 in the Nafion film at the potential of +0.5 V and subsequent stripping from the electrode by differential pulse voltammetry. Under optimal conditions, the sensor can detect 5 nM kynurenine (for the accumulation time of 60 seconds), but the limit of detection can be easily lowered to 0.6 nM by prolonging the accumulation time to 600 seconds. The sensor shows sensitivity of 36.25 μAμM−1cm−2 and 185.50 μAμM−1cm−2 for the accumulation time of 60 and 600 seconds, respectively. The great advantage of the proposed method is easy sensor preparation, employing drop coating method, high sensitivity, short total analysis time, and no need for sample preparation. The method was validated for linearity, precision, accuracy (using a high-performance liquid chromatography), selectivity (towards tryptophan metabolites and different amino acids), and recovery. The comprehensive microscopic and electrochemical characterization of the Nafion/GCE was also conducted with different methods including atomic force microscopy (AFM), optical profilometry, time-of-flight secondary ion mass spectrometry (TOF-SIMS), electrochemical impedance spectroscopy (EIS), and cyclic voltammetry (CV). The method has been applied with satisfactory results for determination of kynurenine concentration in a culture medium collected from the human ovarian carcinoma cells SK-OV-3 and to measure IDO enzyme activity in the cancer cell extracts.

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