Preparation and Application of Keggin Silicomolybdic acid Modified Electrode

Mapping Intimacies ◽

10.21203/rs.2.22798/v1 ◽

2020 ◽

Author(s):

Miao Liu ◽

Dong hui Li ◽

Ming xuan Jia

Keyword(s):

Glassy Carbon Electrode ◽

Modified Electrode ◽

Glassy Carbon ◽

Photoelectron Spectroscopy ◽

Limit Of Detection ◽

Differential Pulse ◽

Carbon Electrode ◽

X Ray ◽

Linear Relationships

Abstract An innovative method for the determination of isoniazid tablets is studied through electrochemical method for the modification of glassy carbon electrode (GCE). Polyoxomolybdate, with stable structures, has not been widely used for the determination of substance. In this study, the mentioned polyoxomolybdate was characterized by Fourier transform infrared spectroscopy (FT-IR), UV-vis, X-ray diffraction (XRD), Atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS), and used to modify the glassy carbon electrode (GCE). The electrochemical performance of the polyoxomolybdate@GCE was investigated with cyclic voltammetry (CV) and differential pulse voltammetry (DPV), compared with the unmodified electrode, the proposed polyoxomolybdate modified electrode exhibited strong electro-catalytic activities towards isoniazid (INH). Under the optimized conditions, there was linear relationships between the DPV peak currents and the concentrations in the range of 1 × 10 -7 g/L to 3 × 10 -7 g/L for INH (R 2 = 0.9979), with the limit of detection (LOD) of 0.024 μg/L (based on S/N = 3). The modified electrode has proper reproducibility (RSD < 5%), stability, response time (< 3 min) and lifetime (up to 6 days).

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Preparation and Application of Keggin Silicomolybdic acid Modified Electrode

10.21203/rs.2.24140/v1 ◽

2020 ◽

Author(s):

Miao Liu ◽

Mingxuan Jia ◽

Dong Hui Li

Keyword(s):

Glassy Carbon Electrode ◽

Modified Electrode ◽

Glassy Carbon ◽

Photoelectron Spectroscopy ◽

Limit Of Detection ◽

Differential Pulse ◽

Carbon Electrode ◽

X Ray ◽

Linear Relationships

Abstract An innovative method for the determination of isoniazid tablets is studied through electrochemical method for the modification of glassy carbon electrode (GCE). Polyoxomolybdate, with stable structures, has not been widely used for the determination of substance. In this study, the mentioned polyoxomolybdate was characterized by Fourier transform infrared spectroscopy (FT-IR), UV-vis, X-ray diffraction (XRD), Atomic force microscope (AFM) and X-ray photoelectron spectroscopy (XPS), and used to modify the glassy carbon electrode. The electrochemical performance of the polyoxomolybdate@GCE was investigated with cyclic voltammetry (CV) and differential pulse voltammetry (DPV), compared with the unmodified electrode, the proposed polyoxomolybdate modified electrode exhibited strong electro-catalytic activities towards isoniazid (INH). Under the optimized conditions, there was linear relationships between the DPV peak currents and the concentrations in the range of 1 × 10 -7 g/L to 3 × 10 -7 g/L for INH (R 2 = 0.9979), with the limit of detection (LOD) of 0.024 μg/L (based on S/N = 3). The modified electrode has proper reproducibility (RSD < 5%), stability, response time (< 3 min) and lifetime (up to 6 days).

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Electrocatalytic Response and Determination of Noradrenaline in the Presence of L-Ascorbic and Uric Acids with Poly(Eriochrome Black T)-Modified Electrode

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc20071177 ◽

2007 ◽

Vol 72 (9) ◽

pp. 1177-1188 ◽

Cited By ~ 7

Author(s):

Xinhua Lin ◽

Wei Li ◽

Hong Yao ◽

Yuanyuan Sun ◽

Liying Huang ◽

...

Keyword(s):

Glassy Carbon Electrode ◽

Modified Electrode ◽

Glassy Carbon ◽

Dynamic Range ◽

Differential Pulse ◽

Carbon Electrode ◽

Modified Glassy Carbon Electrode ◽

Eriochrome Black T ◽

Wide Linear Dynamic Range

A poly(Eriochrome Black T) chemically modified glassy carbon electrode modified with Eriochrome Black T was prepared by cyclic voltammetry. The modified electrode showed an excellent electrocatalytic activity in oxidation of noradrenaline (NA) and could separate its electrochemical responses from those of L-ascorbic acid (AA) and uric acid (UA). Differences of the oxidation peak potentials for NA-AA and UA-NA were about 150 mV. The responses to NA, AA and UA of the modified electrode are relatively independent. Using differential pulse voltammetry, the peak currents of NA at modified glassy carbon electrode increased linearly with the concentration of NA from 0.5 to 100 μmol l-1. The detection limit was 0.2 μmol l-1. With the modified electrode, UA could be selectively determined in the presence of AA. The method showing a wide linear dynamic range and excellent sensitivity was successfully applied to the determination of NA in pharmaceutical injections and various samples.

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Voltammetry Determination of Cefotaxime on Zinc Oxide Nanorod Modified Electrode

Current Pharmaceutical Analysis ◽

10.2174/1573412915666190716140230 ◽

2020 ◽

Vol 17 (1) ◽

pp. 40-46

Author(s):

Vanitha Vasantharaghavan ◽

Ravichandran Cingaram

Keyword(s):

Zinc Oxide ◽

Glassy Carbon Electrode ◽

Modified Electrode ◽

Glassy Carbon ◽

Dynamic Range ◽

Limit Of Detection ◽

Accurate Determination ◽

Voltammetric Determination ◽

Carbon Electrode

Background: The Glassy Carbon Electrode (GCE) was modified with zinc oxide nanoparticles to enhance the electrocatalytic activity of the redox behavior of cefotaxime ion. ATOMIC Force Microscopy (AFM) photographic studies showed the nanorod like structure of the zinc oxide, which was coated uniformly on the electrode surface. Methods: The zinc oxide nanorod modified electrode was used as novel voltammetric determination of cefotaxime. The results of voltammetric behavior are satisfactory in the electro oxidation of cefotaxime, and exhibit considerable improvement compared to glassy carbon electrode. Results: Under the optimized experimental conditions, the ZnO nanorod modified electrode exhibit better linear dynamic range from 300 ppb to 700 ppb with lower limit of detection 200 ppb for the stripping voltammetric determination of cefotaxime. Conclusion: The pharmaceutical and clinical formulation of cefotaxime was successfully applied for accurate determination of trace amounts on ZnO nanomateials modified electrode.

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Determination of Mercury (II) Ion on Aryl Amide-Type Podand-Modified Glassy Carbon Electrode

International Journal of Electrochemistry ◽

10.4061/2011/529415 ◽

2011 ◽

Vol 2011 ◽

pp. 1-6 ◽

Cited By ~ 4

Author(s):

Sevgi Güney ◽

Gülcemal Yıldız ◽

Gönül Yapar

Keyword(s):

Glassy Carbon Electrode ◽

Modified Electrode ◽

Glassy Carbon ◽

Reference Electrode ◽

Differential Pulse ◽

Acetate Buffer Solution ◽

Carbon Electrode ◽

Modified Glassy Carbon Electrode ◽

Buffer Solution

A new voltammetric sensor based on an aryl amide type podand, 1,8-bis(o-amidophenoxy)-3,6-dioxaoctane, (AAP) modified glassy carbon electrode, was described for the determination of trace level of mercury (II) ion by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). A well-defined anodic peak corresponding to the oxidation of mercury on proposed electrode was obtained at 0.2 V versus Ag/AgCl reference electrode. The effect of experimental parameters on differential voltammetric peak currents was investigated in acetate buffer solution of pH 7.0 containing 1 × 10−1 mol L−1NaCl. Mercury (II) ion was preconcentrated at the modified electrode by forming complex with AAP under proper conditions and then reduced on the surface of the electrode. Interferences of Cu2+, Pb2+, Fe3+, Cd2+, and Zn2+ions were also studied at two different concentration ratios with respect to mercury (II) ions. The modified electrode was applied to the determination of mercury (II) ions in seawater sample.

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Electrocatalytic Property Toward Dopamine and Uric Acid of the Nanoparticles TiO2 Modified Electrode

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.785-786.508 ◽

2013 ◽

Vol 785-786 ◽

pp. 508-511

Author(s):

Ying Zhang ◽

Guo Bao Li ◽

Qiu Xia Yang

Keyword(s):

Uric Acid ◽

Linear Relationship ◽

Glassy Carbon Electrode ◽

Modified Electrode ◽

Glassy Carbon ◽

Differential Pulse ◽

Carbon Electrode ◽

Oxidation Peak ◽

Good Electrocatalytic Activity

The titanium sol was prepared by depositing the organic titanium on glassy carbon electrode surface. Electrophoresis time and the applied voltage as well can markedly influence the electrochemical behavior of the nanoTiO2film. In contrast with bare glassy carbon electrode, the nanoTiO2film on glassy carbon electrode had a good electrocatalytic activity to dopamine (DA) and uric acid (UA) in PBS solution. The result showed that there was a linear relationship between the oxidation peak currents and the concentration of DA from 8.0×10-6to 4.0×10-4mol·L-1by differential pulse voltammetry (DPV) and there was a linear relationship between the oxidation peak currents and the concentration of UA from 8×10-6to 1.0×10-3mol·L-1. This modified electrode was quite effective to detect DA and UA in simultaneous determination of these species in a mixture.

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Simultaneous Determination of Hydroquinone and Catechol at Poly-Histidine Film Modified Glassy Carbon Electrode

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.781-784.89 ◽

2013 ◽

Vol 781-784 ◽

pp. 89-92

Author(s):

Qiu Xia Yang ◽

Wei Ping Sui ◽

Da Wei Fan ◽

Guo Bao Li

Keyword(s):

Simultaneous Determination ◽

Glassy Carbon Electrode ◽

Modified Electrode ◽

Glassy Carbon ◽

Differential Pulse ◽

Electrode Reaction ◽

Carbon Electrode ◽

Selective Determination ◽

Peak Separation

The poly-histidine (poly-HTD) film was prepared at glassy carbon electrode by electropolymerization, and its electrochemical behavior was investigated by cyclic voltammetry. Results show that the behavior of this poly-HTD film is in good agreement with quasi-reversible process characteristic. At low scan rates, the electronic transfer process of electrode reaction is controlled by surface process. At this poly-HTD film modified electrode, an excellent electrocatalytic ability towards the redox of hydroquinone (HQ) and catechol (CC) with decrease of the overpotential and improvement of the redox peak currents was found. Differential pulse voltammetry was used for the simultaneous determination of HQ and CC in their mixture, and the peak-to-peak separation ΔEpfor HQ and CC was 110 mV. Therefore, this polymer modified electrode can be used for the simultaneously selective determination of HQ and CC without interference with each other.

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Improved Voltammetric Determination of Kynurenine at the Nafion Covered Glassy Carbon Electrode – Application in Samples Delivered from Human Cancer Cells

International Journal of Tryptophan Research ◽

10.1177/11786469211023468 ◽

2021 ◽

Vol 14 ◽

pp. 117864692110234

Author(s):

Ilona Sadok ◽

Katarzyna Tyszczuk-Rotko ◽

Robert Mroczka ◽

Jędrzej Kozak ◽

Magdalena Staniszewska

Keyword(s):

Glassy Carbon Electrode ◽

Glassy Carbon ◽

Limit Of Detection ◽

Accurate Determination ◽

Differential Pulse ◽

Carbon Electrode ◽

Reliable Determination ◽

Accumulation Time ◽

Cell Extracts

Nowadays, development of analytical methods responding to a need for rapid and accurate determination of human metabolites is highly desirable. Herein, an electrochemical method employing a Nafion-coated glassy carbon electrode (Nafion/GCE) has been developed for reliable determination of kynurenine (a key tryptophan metabolite) using a differential pulse adsorptive stripping voltammetry. To our knowledge, this is the first analytical method to allow for kynurenine determination at the Nafion-coated electrode. The methodology involves kynurenine pre-concentration in 0.1 M H2SO4 in the Nafion film at the potential of +0.5 V and subsequent stripping from the electrode by differential pulse voltammetry. Under optimal conditions, the sensor can detect 5 nM kynurenine (for the accumulation time of 60 seconds), but the limit of detection can be easily lowered to 0.6 nM by prolonging the accumulation time to 600 seconds. The sensor shows sensitivity of 36.25 μAμM−1cm−2 and 185.50 μAμM−1cm−2 for the accumulation time of 60 and 600 seconds, respectively. The great advantage of the proposed method is easy sensor preparation, employing drop coating method, high sensitivity, short total analysis time, and no need for sample preparation. The method was validated for linearity, precision, accuracy (using a high-performance liquid chromatography), selectivity (towards tryptophan metabolites and different amino acids), and recovery. The comprehensive microscopic and electrochemical characterization of the Nafion/GCE was also conducted with different methods including atomic force microscopy (AFM), optical profilometry, time-of-flight secondary ion mass spectrometry (TOF-SIMS), electrochemical impedance spectroscopy (EIS), and cyclic voltammetry (CV). The method has been applied with satisfactory results for determination of kynurenine concentration in a culture medium collected from the human ovarian carcinoma cells SK-OV-3 and to measure IDO enzyme activity in the cancer cell extracts.

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Simultaneous electrochemical sensing of dihydroxy benzene isomers at cost-effective allura red polymeric film modified glassy carbon electrode

Journal of Analytical Science & Technology ◽

10.1186/s40543-021-00270-w ◽

2021 ◽

Vol 12 (1) ◽

Author(s):

Pattan-Siddappa Ganesh ◽

Ganesh Shimoga ◽

Seok-Han Lee ◽

Sang-Youn Kim ◽

Eno E. Ebenso

Keyword(s):

Glassy Carbon Electrode ◽

Glassy Carbon ◽

Limit Of Detection ◽

Tap Water ◽

Differential Pulse ◽

Oxidation Potential ◽

Electrochemical Sensing ◽

Carbon Electrode ◽

Buffer Solution ◽

Allura Red

Abstract Background A simple and simultaneous electrochemical sensing platform was fabricated by electropolymerization of allura red on glassy carbon electrode (GCE) for the interference-free detection of dihydroxy benzene isomers. Methods The modified working electrode was characterized by electrochemical and field emission scanning electron microscopy methods. The modified electrode showed excellent electrocatalytic activity for the electrooxidation of catechol (CC) and hydroquinone (HQ) at physiological pH of 7.4 by cyclic voltammetric (CV) and differential pulse voltammetric (DPV) techniques. Results The effective split in the overlapped oxidation signal of CC and HQ was achieved in a binary mixture with peak to peak separation of 0.102 V and 0.103 V by CV and DPV techniques. The electrode kinetics was found to be adsorption-controlled. The oxidation potential directly depends on the pH of the buffer solution, and it witnessed the transfer of equal number of protons and electrons in the redox phenomenon. Conclusions The limit of detection (LOD) for CC and HQ was calculated to be 0.126 μM and 0.132 μM in the linear range of 0 to 80.0 μM and 0 to 110.0 μM, respectively, by ultra-sensitive DPV technique. The practical applicability of the proposed sensor was evaluated for tap water sample analysis, and good recovery rates were observed. Graphical abstract Electrocatalytic interaction of ALR/GCE with dihydroxy benzene isomers.

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