Association between Paraoxonase 1(PON1) Gene Polymorphisms and PON1 Enzyme Activity in Indian Patients with Coronary Artery Disease (CAD)

2019 ◽  
Vol 16 (3) ◽  
pp. 219-229
Author(s):  
Renuka Munshi ◽  
Falguni Panchal ◽  
Ajay Chaurasia ◽  
Girish Rajadhyaksha
Keyword(s):  
Coronary Artery Disease ◽  
Enzyme Activity ◽  
Coronary Artery ◽  
Gene Polymorphisms ◽  
Paraoxonase 1 ◽  
Pon1 Gene ◽  
Indian Patients ◽  
Artery Disease

PP-209: PARAOXONASE 1 ENZYME ACTIVITY IN METABOLIC SYNDROME PATIENTS WITHOUT CORONARY ARTERY DISEASE

2011 ◽  
Vol 147 ◽  
pp. S148
Author(s):  
E. Yucel ◽  
A. Aydinlar ◽  
A. Aydin Kaderli ◽  
T. Senturk ◽  
S. Gunay ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Metabolic Syndrome ◽  
Enzyme Activity ◽  
Coronary Artery ◽  
Paraoxonase 1 ◽  
Artery Disease

Association of PON1 gene polymorphisms and enzymatic activity with risk of coronary artery disease

2021 ◽  
Vol 17 (1) ◽  
pp. 119-126
Author(s):  
Charuta Godbole ◽  
Saket Thaker ◽  
Prafulla Kerkar ◽  
Milind Nadkar ◽  
Nithya Gogtay ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Enzymatic Activity ◽  
Gene Polymorphisms ◽  
Pon1 Activity ◽  
Pon1 Gene ◽  
Artery Disease ◽  
Pon1 Polymorphisms ◽  
Serum Pon1 Activity ◽  
Control Study

Background: The present case–control study evaluated the association of PON1 gene polymorphisms and enzyme activity in the western Indian population. Materials & methods: Angiographically proven coronary artery disease (CAD) formed the cases. PON1 polymorphisms (Q192R, L55M) and enzymatic activity (paraoxonase) were assessed. Results: A total of 502 participants (251 per group) were studied. PON1 Q192R and L55M polymorphisms were not associated with the risk of CAD. Notably, a weak association was observed between Q192R polymorphisms and the risk of CAD. CAD patients had significantly lower PON1 enzymatic activity (U/L) as compared with the controls regardless of the genotype. Conclusion: Low serum PON1 activity was confirmed to be an independent predictor for the risk of CAD.

scholarly journals Paraoxonase 1 gene polymorphisms and enzyme activities in coronary artery disease and its relationship to serum lipids and glycemia

2016 ◽  
Vol 86 (4) ◽  
pp. 350-357 ◽  
Author(s):  
Osvaldo Fridman ◽  
Luis Gariglio ◽  
Stephanie Riviere ◽  
Rafael Porcile ◽  
Alicia Fuchs ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Enzyme Activities ◽  
Gene Polymorphisms ◽  
Serum Lipids ◽  
Paraoxonase 1 ◽  
Artery Disease

scholarly journals Paraoxonase 1 gene polymorphisms contribute to coronary artery disease risk among north Indians

2009 ◽  
Vol 63 (8) ◽  
pp. 335 ◽  
Author(s):  
S Mastana ◽  
S Agrawal ◽  
Gaurav Tripathi ◽  
R Prajnya ◽  
Nakul Sinha ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Gene Polymorphisms ◽  
Disease Risk ◽  
Paraoxonase 1 ◽  
Coronary Artery Disease Risk ◽  
North Indians ◽  
Artery Disease

scholarly journals Paraoxonase 1 Gene Polymorphisms (Q192R and L55M) Are Associated with Coronary Artery Disease Susceptibility in Asian Indians

2018 ◽  
pp. 38-47 ◽  
Author(s):  
Sumanpreet Kaur ◽  
Gurjit Kaur Bhatti ◽  
Rajesh Vijayvergiya ◽  
Puneetpal Singh ◽  
Sarabjit Singh Mastana ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Gene Polymorphisms ◽  
Asian Indians ◽  
Disease Susceptibility ◽  
Paraoxonase 1 ◽  
Artery Disease
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