Anorexia Nervosa and Salivary Gland Enlargement

1982 ◽  
Vol 11 (3) ◽  
pp. 255-261 ◽  
Author(s):  
B. Timothy Walsh ◽  
Charles B. Croft ◽  
Jack L. Katz
Keyword(s):  
Anorexia Nervosa ◽  
Salivary Gland ◽  
Salivary Glands ◽  
Eating Habits ◽  
Normal Weight ◽  
Nutritional Deficiencies ◽  
Salivary Gland Enlargement ◽  
Gland Enlargement

Enlargement of the salivary glands can occur in patients with anorexia nervosa (AN). This enlargement appears to be related to both the nutritional deficiencies and the bizarre eating habits (particularly the bulimia and vomiting) characteristic of these patients. In some patients, the salivary gland enlargement persists despite return to normal weight. Three patients illustrating this finding are described and the implications of this association between AN and salivary gland enlargement are discussed.

scholarly journals Salivary gland enlargement and sialorrhoea in dogs with spirocercosis: A retrospective and prospective study of 298 cases

2012 ◽  
Vol 83 (1) ◽  
Author(s):  
Liesel L. Van der Merwe ◽  
Jevan Christie ◽  
Sarah J. Clift ◽  
Eran Dvir
Keyword(s):  
Salivary Gland ◽  
Prospective Study ◽  
Salivary Glands ◽  
Clinical Signs ◽  
Neoplastic Transformation ◽  
Whitney Test ◽  
Mann Whitney Test ◽  
Salivary Gland Enlargement ◽  
Canine Spirocercosis ◽  
Gland Enlargement

This longitudinal cross-sectional clinical study investigated the incidence of sialorrhoea in dogs with spirocercosis and determined whether breed, body weight and the extent of the oesophageal involvement was associated with this presentation. A retrospective analysis was performed on the medical records of 233 dogs and information pertaining to 65 dogs was collected as part of a prospective study. All the animals were client-owned. Patients from the retrospective study underwent thoracic radiography or oesophageal endoscopy to diagnose and characterise the infection and were placed on therapy with a macrocyclic lactone, whereas the patients in the prospective study had both radiography and endoscopy routinely performed and biopsies of the oesophageal nodules collected where possible. Tru-cut biopsies of affected salivary glands were taken in 10 of 13 patients demonstrating clinical signs of sialorrhoea and salivary gland enlargement. The entire salivary gland was sectioned in an additional three dogs with spirocercosis and no sialorrhoea that were presented for post mortem examination. Sialorrhoea was present in 33/298 cases (11%). Fox terrier breeds were over-represented in the patients with sialorrhoea, comprising 36% of cases, whereas they only comprised 1.5% of the patients without sialorrhoea (p < 0.001, chi squared test) and 5% of the combined group. Dogs weighing 12 kg or less were significantly over-represented in the sialorrhoea group, 69% versus 19.5% (p < 0.001, chi square test). Age was not significantly different between the two groups (p < 0.08, Mann-Whitney test). The number of oesophageal nodules per case was significantly higher in the non-sialorrhoea cases (p = 0.048, Mann-Whitney test). The prevalence of distal oesophageal and lower oesophageal sphincter involvement, and neoplastic transformation of the nodules were not statistically different between the two groups. None of the fox terriers in either group showed neoplastic transformation of the parasitic nodules even though they were over-represented as a breed. Mandibular salivary glands were affected in 86% of cases showing sialorrhoea. Histopathology revealed acinar hyperplasia in all cases with concurrent necrosis detected in only two cases.Sialorrhoea and salivary gland enlargement has an incidence of 11% (33/298 cases) in canine spirocercosis. Small breeds (≤ 12 kg) and particularly fox terrier breeds are over-represented in the group demonstrating sialorrhoea and this appeared to be the only risk factor.The conclusion was that sialorrhoea secondary to canine spirocercosis occurs frequently and its presence should prompt further investigation for oesophageal and gastro-intestinal disease. Severely affected patients can be managed with phenobarbitone to control the dysphagia in addition to the routine macrocyclic lactones treatment.

Salivary Gland Enlargement and Phenylbutazone

BMJ ◽  
1966 ◽  
Vol 2 (5505) ◽  
pp. 113-113 ◽  
Author(s):  
R. D. Rogers
Keyword(s):  
Salivary Gland ◽  
Salivary Gland Enlargement ◽  
Gland Enlargement

Salivary gland enlargement and elevated serum amylase in bulimia nervosa

1999 ◽  
Vol 45 (11) ◽  
pp. 1520-1522 ◽  
Author(s):  
Eran D Metzger ◽  
Jeffrey M Levine ◽  
Colin R McArdle ◽  
Barbara E Wolfe ◽  
David C Jimerson
Keyword(s):  
Salivary Gland ◽  
Bulimia Nervosa ◽  
Serum Amylase ◽  
Elevated Serum ◽  
Salivary Gland Enlargement ◽  
Gland Enlargement

Thiazolidinediones and Salivary Gland Enlargement

Drug Safety ◽  
2007 ◽  
Vol 30 (10) ◽  
pp. 919-990
Author(s):  
M H Monster-Simons ◽  
J Labadie ◽  
A C van Grootheest
Keyword(s):  
Salivary Gland ◽  
Salivary Gland Enlargement ◽  
Gland Enlargement

scholarly journals Saliva and Blood Asprosin Hormone Concentration Associated with Obesity

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Kader Ugur ◽  
Suleyman Aydin
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Weight Control ◽  
Normal Weight ◽  
Class Iii ◽  
Tissue Mass ◽  
Obese Class ◽  
Gland Tissue ◽  
Treatment Of Obesity ◽  
Normal Weight Control

Background. The aim was to investigate the amounts of saliva and serum asprosin in order to determine whether it is related to obesity and whether salivary glands synthesize asprosin or not.Methods. A total of 116 underweight, normal weight, overweight, and obese (class I, class II, and class III) volunteers participated in the study. Saliva and blood samples were collected simultaneously from the participants. The amounts of asprosin in saliva, salivary gland tissue supernatants, and bloods were determined by ELISA, whereas asprosin synthesis sites of salivary gland tissues were determined immunohistochemically.Results. The amount of asprosin from the lowest to the highest was in the order as follows: underweight, normal weight (control), overweight, and obese classes I and III. The lowest level of asprosin was detected in underweight individuals. It was also found that the interlobular striated ducts and the interlobular ducts of the submandibular and parotid salivary glands produce asprosin. According to these data, the asprosin level is related with obesity as the amount increases in accordance with increasing body mass index (BMI). On the other hand, there is also a relationship between the underweight and asprosin because the amount decreases with BMI decrease.Conclusions. Asprosin, a new adipokine, may be a novel indicator of adipose tissue mass. Therefore, we anticipate that antiasprosin preparations may be an alternative in the treatment of obesity in the future.

Sign in / Sign up

Export Citation Format

Share Document