scholarly journals Health Care and Precision Medicine Research: Analysis of a Scalable Data Science Platform (Preprint)

2018 ◽  
Author(s):  
Jacob McPadden ◽  
Thomas JS Durant ◽  
Dustin R Bunch ◽  
Andreas Coppi ◽  
Nathaniel Price ◽  
...  
Keyword(s):  
Health Care ◽  
Big Data ◽  
Precision Medicine ◽  
Open Source ◽  
Real Time ◽  
Data Science ◽  
Patient Monitoring ◽  
Medicine Research ◽  
Health Care Data ◽  
Precision Medicine Research

BACKGROUND Health care data are increasing in volume and complexity. Storing and analyzing these data to implement precision medicine initiatives and data-driven research has exceeded the capabilities of traditional computer systems. Modern big data platforms must be adapted to the specific demands of health care and designed for scalability and growth. OBJECTIVE The objectives of our study were to (1) demonstrate the implementation of a data science platform built on open source technology within a large, academic health care system and (2) describe 2 computational health care applications built on such a platform. METHODS We deployed a data science platform based on several open source technologies to support real-time, big data workloads. We developed data-acquisition workflows for Apache Storm and NiFi in Java and Python to capture patient monitoring and laboratory data for downstream analytics. RESULTS Emerging data management approaches, along with open source technologies such as Hadoop, can be used to create integrated data lakes to store large, real-time datasets. This infrastructure also provides a robust analytics platform where health care and biomedical research data can be analyzed in near real time for precision medicine and computational health care use cases. CONCLUSIONS The implementation and use of integrated data science platforms offer organizations the opportunity to combine traditional datasets, including data from the electronic health record, with emerging big data sources, such as continuous patient monitoring and real-time laboratory results. These platforms can enable cost-effective and scalable analytics for the information that will be key to the delivery of precision medicine initiatives. Organizations that can take advantage of the technical advances found in data science platforms will have the opportunity to provide comprehensive access to health care data for computational health care and precision medicine research.

scholarly journals Health Care and Precision Medicine Research: Analysis of a Scalable Data Science Platform

10.2196/13043 ◽  
2019 ◽  
Vol 21 (4) ◽  
pp. e13043 ◽  
Author(s):  
Jacob McPadden ◽  
Thomas JS Durant ◽  
Dustin R Bunch ◽  
Andreas Coppi ◽  
Nathaniel Price ◽  
...  
Keyword(s):  
Health Care ◽  
Precision Medicine ◽  
Data Science ◽  
Medicine Research ◽  
Precision Medicine Research ◽  
Research Analysis

Big Data, Surveillance Capitalism, and Precision Medicine: Challenges for Privacy

2021 ◽  
Vol 49 (4) ◽  
pp. 666-676
Author(s):  
Mark A. Rothstein
Keyword(s):  
Big Data ◽  
Precision Medicine ◽  
Health Information ◽  
Medicine Research ◽  
Amount Of Information ◽  
Data Surveillance ◽  
Precision Medicine Research

AbstractSurveillance capitalism companies, such as Google and Facebook, have substantially increased the amount of information collected, analyzed, and monetized, including health information increasingly used in precision medicine research, thereby presenting great challenges for health privacy.

scholarly journals Can Precision Medicine Reduce the Burden of Diabetes?

2019 ◽  
Vol 29 (Supp) ◽  
pp. 669-674
Author(s):  
Wylie Burke ◽  
Susan Brown Trinidad ◽  
David Schenck
Keyword(s):  
Health Care ◽  
Precision Medicine ◽  
Health Care Access ◽  
Collective Responsibility ◽  
Good Health ◽  
Medicine Research ◽  
Care Access ◽  
Scant Attention ◽  
Health Promoting ◽  
Precision Medicine Research

Precision medicine is a new health care concept intended to hasten progress toward individualized treatment and, in so doing, to improve everyone’s opportunity to enjoy good health. Yet, this concept pays scant attention to opportunities for change in the social determinants that are the major driv­ers of health. Precision medicine research is likely to generate improvements in medical care but may have the unintended conse­quence of worsening existing disparities in health care access. For prevention, precision medicine emphasizes comprehensive risk prediction and individual efforts to accom­plish risk reduction. The application of the precision medicine vision to type 2 diabe­tes, a growing threat to population health, fails to acknowledge collective responsibility for a health-promoting society.Ethn Dis. 2019;29(Suppl 3):669-674;doi:10.18865/ed.29.S3.669

scholarly journals Modeling Research Topics for Artificial Intelligence Applications in Medicine: Latent Dirichlet Allocation Application Study

10.2196/15511 ◽  
2019 ◽  
Vol 21 (11) ◽  
pp. e15511 ◽  
Author(s):  
Bach Xuan Tran ◽  
Son Nghiem ◽  
Oz Sahin ◽  
Tuan Manh Vu ◽  
Giang Hai Ha ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Health Care ◽  
Precision Medicine ◽  
Data Science ◽  
Latent Dirichlet Allocation ◽  
Developed Countries ◽  
Theory And Practice ◽  
Clinical Practices ◽  
Research Topics ◽  
Dirichlet Allocation

Background Artificial intelligence (AI)–based technologies develop rapidly and have myriad applications in medicine and health care. However, there is a lack of comprehensive reporting on the productivity, workflow, topics, and research landscape of AI in this field. Objective This study aimed to evaluate the global development of scientific publications and constructed interdisciplinary research topics on the theory and practice of AI in medicine from 1977 to 2018. Methods We obtained bibliographic data and abstract contents of publications published between 1977 and 2018 from the Web of Science database. A total of 27,451 eligible articles were analyzed. Research topics were classified by latent Dirichlet allocation, and principal component analysis was used to identify the construct of the research landscape. Results The applications of AI have mainly impacted clinical settings (enhanced prognosis and diagnosis, robot-assisted surgery, and rehabilitation), data science and precision medicine (collecting individual data for precision medicine), and policy making (raising ethical and legal issues, especially regarding privacy and confidentiality of data). However, AI applications have not been commonly used in resource-poor settings due to the limit in infrastructure and human resources. Conclusions The application of AI in medicine has grown rapidly and focuses on three leading platforms: clinical practices, clinical material, and policies. AI might be one of the methods to narrow down the inequality in health care and medicine between developing and developed countries. Technology transfer and support from developed countries are essential measures for the advancement of AI application in health care in developing countries.

Increasing inclusivity in precision medicine research: Views of individuals who are deaf and hard of hearing

2021 ◽  
Author(s):  
Diana C. Garofalo ◽  
Howard A. Rosenblum ◽  
Yuan Zhang ◽  
Ying Chen ◽  
Paul S. Appelbaum ◽  
...  
Keyword(s):  
Precision Medicine ◽  
Hard Of Hearing ◽  
Medicine Research ◽  
Precision Medicine Research
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