scholarly journals A Review of Clinical Studies of Chinese Medicine Treatment of Polycystic Kidney Disease Using the CNKI Database

2021 ◽  
Vol 42 (3) ◽  
pp. 225-238
Author(s):  
Ah-ra Ju ◽  
Mi-so Park ◽  
Yo-sup Choi ◽  
Won-jung Choo ◽  
Hye-kyung Baek ◽  
...  

Objective: This research reviews and investigates the trends in recent clinical studies of polycystic kidney disease (PKD) in China. Method: We searched for clinical studies discussing Oriental medicine-based treatments for PKD in the China National Knowledge Infrastructure (CNKI) database. Thirteen clinical articles published from 2001 to 2019 were analyzed. The search focused on the authors, publication year, type of study, purposes of study, method and duration of treatment, evaluation criteria, and results of the selected articles. Results: Of the articles from the database, 9 case series and 4 randomized controlled trials (RCTs) were analyzed. Ten articles used herbal medicine; 4 used herbal medicine for external use. Gamigyejibokryeong-hwan was the most common herbal prescription. The most frequently used herb was Polia Sclerotium (茯苓), and Cnidii Rhizoma (川芎) was employed in all the external uses. All 13 studies confirmed the efficacy of Oriental medicine treatments. Conclusion:1. Scientifically designed and more varied clinical studies are required to develop treatments for PKD. 2. The current study could be used as basic data in future clinical studies on treatment and further studies of PKD.

2021 ◽  
Vol 11 (2) ◽  
pp. 39-49
Author(s):  
Letizia Spinelli ◽  
Giuseppe Giugliano ◽  
Giovanni Esposito

Cardiovascular disorders are the main complication in autosomal dominant polycystic kidney disease (ADPKD). contributing to both morbidity and mortality. This review considers clinical studies unveiling cardiovascular features in patients with ADPKD. Additionally, it focuses on basic science studies addressing the dysfunction of the polycystin proteins located in the cardiovascular system as a contributing factor to cardiovascular abnormalities. In particular, the effects of polycystin proteins’ deficiency on the cardiomyocyte function have been considered.


Author(s):  
V.V. Doretskyi ◽  
Y.V. Doretskyi

The review contains information about modern conception ofautosomal–dominant polycystic kidney disease, its genetics, epidemiology, pathogenesis, course, clinical presentation and the results of recent clinical studies


1995 ◽  
Vol 28 (10) ◽  
pp. 1353-1358
Author(s):  
Izumi Yoshida ◽  
Shigeyuki Takeda ◽  
Yukio Miyata ◽  
Morimasa Amemiya ◽  
Youichi Akai ◽  
...  

2021 ◽  
Vol 42 (3) ◽  
pp. 308-322
Author(s):  
Yu-ran Je ◽  
Kyong-lim Kim ◽  
Won-deok Hwang

Objectives: This study investigates the latest clinical studies on Korean medicine treatment of chronic subdural hematoma (CSDH) in China.Methods: A CNKI search investigated the last 10 years of clinical studies of Korean medicine treatments in Chinese medical journals for CSDH. The search focused on authors, publication years, types of studies, purposes of studies, methods and duration of treatment, evaluation criteria, and results of treatment.Results: In 19 studies, there were 14 randomized controlled trials (RCTs), 4 case series, and 1 case-control study. In all 19 studies, Korean medical treatment and Western treatment were combined. Herbal medicine was used in 19 studies and acupuncture treatment in 2 studies. The most frequently used prescription was Hyeolbuchukeo-tang-gagambang, and the most frequently used acupoint was PC6. In all 19 studies, the effectiveness of Korean medicine treatment performed in parallel with Western treatment was confirmed.Conclusions: In this study, Korean medicine combined with Western treatment for CSDH was effective. More clinical studies and case reports are required to develop a guided treatment for CSDH.


2019 ◽  
Vol 49 (7) ◽  
pp. 906-912
Author(s):  
Juliette Garel ◽  
Mathilde Lefebvre ◽  
Marie Cassart ◽  
Valeria Della Valle ◽  
Lucie Guilbaud ◽  
...  

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0178488 ◽  
Author(s):  
Kanishka Sharma ◽  
Anna Caroli ◽  
Le Van Quach ◽  
Katja Petzold ◽  
Michela Bozzetto ◽  
...  

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