scholarly journals Isolated Pulmonary Presentation of Childhood Goodpasture's Disease

Author(s):  
Ketan Kumar ◽  
Joseph L Mathew ◽  
Lesa Dawman ◽  
Ritambhra Nada ◽  
PANKAJ VAIDYA ◽  
...  
2018 ◽  
Vol 90 (6) ◽  
pp. 130-136 ◽  
Author(s):  
M L Bulanova ◽  
D V Potapov ◽  
N M Bulanov ◽  
L V Lysenko(Kozlovskaya)

Goodpasture’s disease (anti-GBM disease) is a rare small vessels vasculitis characterized by the presence of autoantibodies directed against the glomerular basement membrane (GBM) and alveolar basement membrane. Common feature of anti-GBM disease is a combination of rapidly progressive glomerulonephritis and alveolar hemorrhage (pulmonary-renal syndrome). We present a case of atypical disease course in a young male patient who developed alveolar hemorrhage without renal failure. The only symptom of renal involvement was isolated hematuria. Plasmapheresis combined with immunosuppression (cyclophosphamide and corticosteroids) was effective. We present a review of state-of-art data on the pathogenesis and disease course of anti-GBM disease.


2013 ◽  
Vol 12 (11) ◽  
pp. 1101-1108 ◽  
Author(s):  
Franco Dammacco ◽  
Stefano Battaglia ◽  
Loreto Gesualdo ◽  
Vito Racanelli

Author(s):  
David J. Timson ◽  
Richard J. Reece ◽  
James B. Thoden ◽  
Hazel M. Holden ◽  
Andrea L. Utz ◽  
...  

Author(s):  
Jeremy Levy ◽  
Charles Pusey

Antiglomerular basement membrane disease (anti-GBM disease, also known as Goodpasture’s disease) is a rare autoimmune disease caused by pathogenic autoantibodies directed against the noncollagenous, C-terminal domain of the α‎-3 chain of type IV collagen (α‎3(IV)NC1). Immunohistology is characteristic, with linear deposition of IgG (sometimes with IgA or IgM) and complement C3 along the GBMs....


2014 ◽  
Vol 2014 (nov24 1) ◽  
pp. bcr2014206220-bcr2014206220 ◽  
Author(s):  
M. Narayanan ◽  
I. Casimiro ◽  
R. Pichler

2009 ◽  
Vol 3 (1) ◽  
Author(s):  
Christoph Preul ◽  
Jens Gerth ◽  
Sebastian Lang ◽  
Christoph Bergmeier ◽  
Otto W Witte ◽  
...  

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