scholarly journals CENTRAL DIABETES INSIPIDUS AFTER ABDOMINAL SURGERY: A CASE REPORT

2021 ◽  
Author(s):  
Aarti Maharaj ◽  
Kundan Jana ◽  
Kalyana Janga ◽  
Sheldon Greenberg ◽  
Elie Fein
Keyword(s):  
Case Report ◽  
Blood Loss ◽  
Abdominal Surgery ◽  
Diabetes Insipidus ◽  
Pituitary Surgery ◽  
Central Diabetes Insipidus ◽  
Intraoperative Blood Loss ◽  
Prolonged Surgery

Post-operative polyuria due to Diabetes Insipidus is a commonly reported complication of pituitary surgery. However, central DI post abdominal surgery is rare and may be related to pre-existing DI or prolonged surgery with intraoperative blood loss. A thorough workup needs to be done to exclude central DI in such patients.

Central diabetes insipidus in neonate born at 24 weeks of pregnancy – Case report and review of literature

2017 ◽  
Vol 92 (2) ◽  
pp. 205-209
Author(s):  
Dawid Szpecht ◽  
Irmina Nowak ◽  
Agnieszka Ciesielska ◽  
Marta Szymankiewicz ◽  
Janusz Gadzinowski
Keyword(s):  
Case Report ◽  
Diabetes Insipidus ◽  
Central Diabetes Insipidus ◽  
Review Of Literature

Early Copeptin Determination Allows Prompt Diagnosis of Post-Neurosurgical Central Diabetes Insipidus

2019 ◽  
Vol 110 (6) ◽  
pp. 525-534 ◽  
Author(s):  
Alessandro Maria Berton ◽  
Filippo Gatti ◽  
Federica Penner ◽  
Emanuele Varaldo ◽  
Nunzia Prencipe ◽  
...  
Keyword(s):  
Diabetes Insipidus ◽  
Surrogate Marker ◽  
Pituitary Surgery ◽  
Central Diabetes Insipidus ◽  
Optimal Timing ◽  
Vasopressin Release ◽  
Biochemical Alterations ◽  
Post Surgery ◽  
Patients At Risk ◽  
Pituitary Lesion

Introduction: Central diabetes insipidus (CDI) is a frequent complication of pituitary surgery, but its diagnosis lacks standardized criteria. Copeptin, a surrogate marker of arginine vasopressin release, is triggered by psycho-physical stresses such as pituitary surgery. Low postoperative copeptin could predict CDI onset. The aims of this study were the validation of copeptin as a predictor of post-neurosurgical CDI and the identification of the optimal timing for its determination. Methods: Sixty-six consecutive patients operated for a hypothalamic-pituitary lesion were evaluated. Copeptin was determined preoperatively and at 1, 6, 12, 24 and 48 h post-extubation. Fifty-eight patients were reassessed after 3–6 months post-surgery to confirm transient (3 cases) or permanent CDI (5 cases) diagnosis. Results: A marked copeptin peak was identified at 1 h after extubation, when a value below or equal to 12.8 pmol/L had a good accuracy in identifying CDI cases (AUC 0.866, 95% CI 0.751–0.941). Moreover, a copeptin peak above 4.2 pmol/L excluded permanent forms (AUC 1, 95% CI 0.629–1). Regression analysis identified copeptin as the only significant predictor of CDI (OR 0.86, 95% CI 0.75–0.98, p = 0.02). A copeptin T1/T0 ratio below or equal to 1.47 identified patients at risk of isolated biochemical alterations even in the absence of an overt CDI. Conclusions: A prompt increase of copeptin is expected at 1 h after extubation. The absence of this peak is a reliable predictor of post-neurosurgical CDI.

Newly Developed Central Diabetes Insipidus Following Kidney Transplantation: A Case Report

2013 ◽  
Vol 45 (7) ◽  
pp. 2804-2806 ◽  
Author(s):  
K.M. Kim ◽  
S.M. Kim ◽  
J. Lee ◽  
S.Y. Lee ◽  
S.K. Kwon ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Case Report ◽  
Diabetes Insipidus ◽  
Central Diabetes Insipidus
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