scholarly journals Carboplatin-induced Renal Salt Wasting Syndrome in Paediatric Patients with Intracranial Germ Cell Tumours and Concomitant Diabetes Insipidus

2021 ◽  
Author(s):  
Tania Wan ◽  
Joanna Tung ◽  
Samantha Lee ◽  
Alison LT Ma ◽  
Anthony Pak Yin Liu ◽  
...  
Keyword(s):  
Germ Cell ◽  
Diabetes Insipidus ◽  
Germ Cell Tumour ◽  
Case Series ◽  
Salt Wasting ◽  
Renal Salt Wasting ◽  
Wasting Syndrome ◽  
First Case ◽  
Platinum Based Chemotherapy ◽  
Salt Wasting Syndrome

We report the first case series of 14 children with intracranial germ cell tumour (iGCT) and concomitant central diabetes insipidus (DI), who developed hyponatremia secondary to renal salt wasting syndrome (RSWS) following the administration of carboplatin. Clinicians prescribing platinum-based chemotherapy for this group of patients should be alert to the risk of RSWS. Regular monitoring should be performed as hyponatraemia can be asymptomatic until it is severe.

Renal Salt Wasting Syndrome Secondary to Cisplatin-Based Chemotherapy for Lung Cancer: A Case Series

2016 ◽  
Vol 3 ◽  
pp. 77-81 ◽  
Author(s):  
Jun Tanaka ◽  
Katsuyoshi Tomomatsu ◽  
Naoki Hayama ◽  
Masako Sato ◽  
Yukihiro Horio ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Case Series ◽  
Salt Wasting ◽  
Renal Salt Wasting ◽  
Wasting Syndrome ◽  
Salt Wasting Syndrome

Combined Central Diabetes Insipidus and Cerebral Salt Wasting Syndrome in Children

2009 ◽  
Vol 40 (2) ◽  
pp. 84-87 ◽  
Author(s):  
Jainn-Jim Lin ◽  
Kuang-Lin Lin ◽  
Shao-Hsuan Hsia ◽  
Chang-Teng Wu ◽  
Huei-Shyong Wang
Keyword(s):  
Diabetes Insipidus ◽  
Central Diabetes Insipidus ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Salt Wasting Syndrome

scholarly journals Pengelolaan Diabetes Insipidus dengan Cerebral Salt Wasting Syndrome dan Tension Pneumocephalus pada Pasien Pascabedah Eksisi Tumor Pineal

2021 ◽  
Vol 10 (3) ◽  
pp. 182-192
Author(s):  
Dhania A. Santosa ◽  
◽  
Nancy Margareta Rehatta
Keyword(s):  
Brain Injury ◽  
Diabetes Insipidus ◽  
Pineal Tumor ◽  
Secondary Brain Injury ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Tension Pneumocephalus ◽  
Wasting Syndrome ◽  
Salt Wasting Syndrome

Electrolyte imbalance is an often incident in patients underwent neurosurgery and it potentially induces secondary brain injury, leading to a worse outcome, despite successful surgery. Diabetes insipidus is a frequent hypernatremic condition, commonly caused by abnormalities in the hypophysis; but rarely happens due to pineal tumor. A 21-year-old male with preoperative diabetes insipidus experienced episodes of diabetes insipidus complicated by cerebral salt wasting syndrome and tension pneumocephalus after a successful pineal tumor removal surgery. Closed observation on volume status, plasma glucose and electrolyte, along with optimal dose of desmopressin were keys of successful postoperative management in this patient in order to avoid the patient from secondary brain injury. An intensivist plays a key role, mainly in the understanding of intracranial pathophysiology and its implications to fluid and electrolyte balance.

scholarly journals A Case of Severe Hyponatremia Caused by Renal Salt Wasting Syndrome in Oropharyngeal Cancer

2015 ◽  
Vol 118 (8) ◽  
pp. 1046-1052 ◽  
Author(s):  
Taro Fujikawa ◽  
Satoru Shirakura ◽  
Akio Hatanaka ◽  
Wataru Okano ◽  
Takao Tokumaru ◽  
...  
Keyword(s):  
Oropharyngeal Cancer ◽  
Severe Hyponatremia ◽  
Salt Wasting ◽  
Renal Salt Wasting ◽  
Wasting Syndrome ◽  
Salt Wasting Syndrome

scholarly journals Central Neurogenic Diabetes Insipidus, Syndrome of Inappropriate Secretion of Antidiuretic Hormone, and Cerebral Salt-Wasting Syndrome in Traumatic Brain Injury

2012 ◽  
Vol 32 (2) ◽  
pp. e1-e7 ◽  
Author(s):  
Cynthia (Cindi) A. John ◽  
Michael W. Day
Keyword(s):  
Traumatic Brain Injury ◽  
Diabetes Insipidus ◽  
Antidiuretic Hormone ◽  
Cerebral Salt Wasting Syndrome ◽  
Cerebral Salt Wasting ◽  
Salt Wasting ◽  
Wasting Syndrome ◽  
Inappropriate Secretion ◽  
Salt Wasting Syndrome ◽  
Neurogenic Diabetes Insipidus

Central neurogenic diabetes insipidus, syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome are secondary events that affect patients with traumatic brain injury. All 3 syndromes affect both sodium and water balance; however, they have differences in pathophysiology, diagnosis, and treatment. Differentiating between hypernatremia (central neurogenic diabetes insipidus) and the 2 hyponatremia syndromes (syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome) is critical for preventing worsening neurological outcomes in patients with head injuries.

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