PEG mediated synthesis of 6-pyrazinyl-/fused pyrazinylquinazolin-4(3H)-ones using Castro-Stephen coupling, oxidation and cyclocondensation reactions
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A PEG-mediated green synthesis of 6-pyrazinyl-/fused pyrazinylquinazolin- 4(3H)-ones was developed starting from 6-iodo-3-methyl-2-phenylquinazolin- 4(3H)-one by means of quinazolinone-based internal alkyne/1,2-diketone as intermediates using the Castro?Stephen coupling reaction/potassium permanganate mediated oxidation and cyclocondensation reactions.
2017 ◽
Vol 485
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pp. 223-231
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Keyword(s):
2016 ◽
Vol 465
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pp. 121-127
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