scholarly journals Evaluation of myocardial function in the presence of left ventricular hypertrophy in athletes and hypertensive patients

2008 ◽  
Vol 61 (3-4) ◽  
pp. 178-182 ◽  
Author(s):  
Marina Deljanin-Ilic ◽  
Stevan Ilic ◽  
Dragan Djordjevic ◽  
Marija Zdravkovic ◽  
Vladimir Ilic
Keyword(s):  
Left Ventricle ◽  
Left Ventricular Hypertrophy ◽  
Diastolic Function ◽  
Ventricular Hypertrophy ◽  
Myocardial Function ◽  
Systolic Function ◽  
Posterior Wall ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
Imaging Results

Introduction Myocardial hypertrophy of the left ventricle may be of physiological or pathological nature. Distinction of these two types of hypertrophy is sometimes not easy and represents a diagnostic challenge. The aim of the study was to assess global diastolic and regional systolic and diastolic myocardial function in the presence of left ventricular hypertrophy in athletes and hypertensive patients. Material and methods In 18 male hypertensive patients and 14 male athletes global diastolic left ventriclar function and regional systolic and diastolic myocardial function of septum and posterior wall were investigated by pulsed wave tissue Doppler imaging. Results Ejection fraction and left ventricle mass index did not differ significantly between two groups. Hypertensive patients were found to have diastolic dysfunction while athletes had normal left ventricular diastolic function (the difference between the groups was P<0.00001). Index of regional diastolic function of septum as well as of the posterior wall was significantly less in hypertensive patients than in athletes (P<0.00001 for both). In spite of the normal global systolic function the regional systolic function of septum and posterior wall was significantly less in hypertensive patients than in athletes (P<0.02for both). Conclusion The present results show significantly less global and regional diastolic function of hypertrophied myocardium in hypertensive patients than in athletes. In the presence of preserved left ventricular systolic function, the quantification of myocardial velocity revealed significantly lower regional systolic function of septum and posterior wall in hypertensive patients than in athletes.

Assessment of the study of longitudinal systolic function by 2D strain in hypertensive patients

2021 ◽  
Vol 22 (Supplement_2) ◽  
Author(s):  
N Taleb Bendiab ◽  
S Benkhedda ◽  
A Meziane Tani
Keyword(s):  
General Population ◽  
Left Ventricular Hypertrophy ◽  
Diastolic Function ◽  
Longitudinal Strain ◽  
Ventricular Hypertrophy ◽  
Systolic Function ◽  
Left Ventricular ◽  
Systemic Hypertension ◽  
Hypertensive Patients ◽  
2D Strain

Abstract Funding Acknowledgements Type of funding sources: Public hospital(s). Main funding source(s): University Hospital Center of Tlemcen Introduction Hypertension is a well-established risk factor for cardiovascular disease. It causes left ventricular (LV) pressure overload, and, changes in cardiac geometry and LV hypertrophy(LVH). LVH as well as patterns of abnormal geometry have been associated with adverse outcomes.  Global longitudinal strain (GLS) has been used to detect early subclinical myocardial dysfunction in a broad spectrum of cardiac conditions and thereby provides a novel approach for LV risk assessment in patients with hypertension. Purpose This study is intended to assess the clinical and echocardiographic factors associated with and predictive for early impairment of left ventricular function as assessed using GLS evaluation in hypertensive patients. Methods Cross-sectional descriptive study, with a total number of 130 hypertensive and with the objective of evaluating the study of longitudinal function by 2D strain in patients with systemic hypertension with preserved LVEF and the determination of predictors the decrease GLS in this population. A complete study echo cardiographic, including LVEF biplane Simpson method, calculation of left ventricular mass indexed and relative parietal thickness to differentiate the eccentric and concentric LVH, analysis diastolic function and finally the study of longitudinal strain of the LV by the speckle tracking technique (calculation of GLS) to seek a possible decline in the GLS and establish a possible correlation between this drop and power and LVH the diagnosis of subclinical hypertensive heart disease. Results The prevalence of left ventricular hypertrophy (LVH) was found in (66%) in this population. half of the patients (49%) presented a concentric hypertrophy, It was clearly noted that 73%of the patients had a relative wall thickness (RWT)&gt;0.42. Alterations in diastolic function were detected in 89% of the group, 18% had severe diastolic dysfunction with elevation in filling pressure. Analysis of the longitudinal systolic function of the left ventricle took the average GLS as a reference value. The mean GLS was found to be -16.9 ± 3.2%, within a range between -25% and-11.6%. Low GLS values (&gt;-17%) were found in 45.5% of the general population. In particular, 34.4% of the patients had no left ventricular hypertrophy (LVH) and 50.7% of them presented LVH. The average systolic and diastolic blood pressures, taken at the time of echocardiographic analysis, were found higher in the subgroup of hypertensive patients with low GLS. Very low GLS values (&gt;-13%) were found in 11% of the general population. Statistical analysis revealed  significant correlation between the decrease in GLS and diabetes the values of blood pressure and elevated filling pressures. Conclusion  The evaluation of longitudinal systolic function  provides new insight of myocardial function in hypertension that could improve the pathophysiological understanding and identify high-risk heart failure patients eligible for preventive strategies.

scholarly journals Serum Zinc and Selenium Concentrations in Patients with Hypertrophy and Remodelling of the Left Ventricle Secondary to Arterial Hypertension

Antioxidants ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1803
Author(s):  
Paweł Gać ◽  
Karolina Czerwińska ◽  
Małgorzata Poręba ◽  
Adam Prokopowicz ◽  
Helena Martynowicz ◽  
...  
Keyword(s):  
Left Ventricle ◽  
Left Ventricular Hypertrophy ◽  
Arterial Hypertension ◽  
Ventricular Hypertrophy ◽  
Serum Zinc ◽  
Left Ventricular ◽  
Left Ventricular Geometry ◽  
Serum Selenium ◽  
Hypertensive Patients ◽  
Concentric Hypertrophy

The aim of the study was to assess the relationship between serum selenium and zinc concentrations (Se-S and Zn-S) and the left ventricle geometry in patients suffering from arterial hypertension. A total of 78 people with arterial hypertension (mean age: 53.72 ± 12.74 years) participated in the study. Se-S and Zn-S were determined in all patients. The type of left ventricular remodelling and hypertrophy was determined by the left ventricular mass index (LVMI) and relative wall thickness (RWT) measured by echocardiography. Se-S and Zn-S in the whole group were 89.84 ± 18.75 µg/L and 0.86 ± 0.13 mg/L. Normal left ventricular geometry was found in 28.2% of patients; left ventricular hypertrophy (LVH) in 71.8%, including concentric remodelling in 28.2%, concentric hypertrophy in 29.5%, and eccentric hypertrophy in 14.1%. LVH was statistically significantly more frequent in patients with Se-S < median compared to patients with Se-S ≥ median (87.2% vs. 56.4%, p < 0.05), as well as in patients with Zn-S < median compared to patients with Zn-S ≥ median (83.8% vs. 60.9%, p < 0.05). In hypertensive patients, older age, higher LDL cholesterol, higher fasting glucose, lower Se-S, and lower Zn-S were independently associated with LVH. In conclusion, in hypertensive patients, left ventricular hypertrophy may be associated with low levels of selenium and zinc in the serum.

scholarly journals Evaluation of left ventricular hypertrophy in hypertensive patients with echocardiographic myocardial videodensitometry normalized by displacement

2010 ◽  
Vol 10 (4) ◽  
pp. 292-296 ◽  
Author(s):  
Xiao-Zhi Zheng ◽  
Lian-Fang Du ◽  
Hui-Ping Wang
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Ventricular Hypertrophy ◽  
Accurate Determination ◽  
Normal Subjects ◽  
Posterior Wall ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
Tissue Tracking ◽  
Cardiovascular Morbidity And Mortality

Left ventricular hypertrophy (LVH) is an important predictor of cardiovascular morbidity and mortality. To investigate the feasibility of the myocardial grayscale intensity (GI) normalized by displacement (d) to discriminate between healthy and hypertrophic myocardium in hypertensive patients, sixty hypertensive patients and sixty age and sex-matched healthy volunteers were involved in this study. The peak d and the maximal GI [GI(max)] and minimal GI [GI(min)] for the middle interventricular septal (IVS) and the middle posterior wall (PW) at the level of papillary muscle were obtained from the standard parasternal long axis views using tissue tracking (TT) and videodensitometric analysis, respectively. The GI and the cyclic variation of GI (CVGI) normalized by d were calculated. The results showed that the d both for IVS and PW the amplitude of CVGI for IVS in hypertensive patients with LVH were smaller than the ones without LVH and the normal subjects. But, the CVGI/d both for IVS and PW in hypertensive patients with LVH were all greater than the ones without LVH and the normal subjects. Moreover, the parameter, CVGI/d correlated positively with left ventricular mass index (LVMI). So, the method employed in this study, videodensitometric analysis in combination with TT allow objective and accurate determination of LVH and CVGI/d is a sensitive indicator for hypertensive patients with LVH.

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