scholarly journals Chronic necrotizing pulmonary aspergillosis

2011 ◽  
Vol 68 (11) ◽  
pp. 988-991 ◽  
Author(s):  
Aleksandra Lovrenski ◽  
Milana Panjkovic ◽  
Zivka Eri ◽  
Istvan Klem ◽  
Djordje Povazan ◽  
...  

Introduction. Chronic necrotizing pulmonary aspergillosis (CNPA) is a cavitary, infectious process of lung parenchyma with slow progressive course. Vascular invasion and dissemination to other organs are unusual. Case report. We presented a 25-year old man with bilineal acute leukaemia who developed pulmonary and systemic symptoms. Chest CT showed nodular consolidations and cavitary lesions in both lungs. Bronchial biopsy revealed necrotic hyphae but it was negative for Aspergillus by culture. Serum was positive for antibodies to Aspergillus, but it was negative for antigens. A thoracoscopic lung biopsy of the upper left lobe revealed necrosis of lung tissue, with acute and chronic inflammation of the cavity wall and the presence of hyphae consistent with Aspergillus species. Conclusion. Although confirmation of the diagnosis is difficult, a combination of characteristic clinical, radiological and histological findings and either serological results positive for Aspergillus or the isolation of Aspergillus from respiratory samples are highly indicative of CNPA.

2009 ◽  
Vol 58 (1) ◽  
pp. 146-150 ◽  
Author(s):  
Shalini Malhotra ◽  
Shalini Duggal ◽  
Nirmaljeet Kaur Bhatia ◽  
Nishi Sharma ◽  
Charoo Hans

Zygomycosis and aspergillosis are two serious opportunistic fungal infections that are commonly seen in immunocompromised patients. Since both these fungi invade vessels of the arterial system, an early and rapid diagnosis by direct examination of KOH mounts of the relevant clinical sample can confirm the diagnosis. Here, we present an unusual case of a diabetic patient who presented with nasal blockade and bleeding for 2 months, along with occasional haemoptysis for 15 days. On investigation, the patient was diagnosed with a case of rhinocerebral zygomycosis and was treated with amphotericin B (1 mg kg−1 day−1), which was subsequently replaced with liposomal amphotericin B (2 mg kg−1 day−1). However, the patient did not completely respond to therapy as haemoptysis continued. Further investigations revealed the presence of Aspergillus flavus in respiratory specimens. Thus, a final diagnosis of rhinocerebral zygomycosis with pulmonary aspergillosis in a non-HIV-infected patient was made, but due to infection of two vital sites by these fungi, the patient could not be saved.


Author(s):  
Harsha Vardhan Gowthamnath ◽  
J.S. Jesija ◽  
K. Saraswathi Gopal

2016 ◽  
Vol 3 (1) ◽  
pp. 1-4
Author(s):  
Leena James ◽  
Tejavathi Nagaraj ◽  
Haritma Nigam ◽  
Yogesh

2019 ◽  
Vol 02 (03) ◽  
Author(s):  
Tika Ram Bhandari ◽  
Sudha Shahi ◽  
Sarfaraz Alam Khan

1986 ◽  
Vol 27 (3) ◽  
pp. 170-174 ◽  
Author(s):  
Toshiki Inokuchi ◽  
Koji Kuboki ◽  
Hisaya Tada ◽  
Kimio Hosaka ◽  
Sho Isogai

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
V. Nagalaxmi ◽  
Mithare Sangmesh ◽  
Kotya Naik Maloth ◽  
Srikanth Kodangal ◽  
Vani Chappidi ◽  
...  

Ameloblastoma is a benign odontogenic neoplasm which frequently affects the mandible. The term ameloblastoma includes several clinicoradiological and histological types. Apart from the most commonly encountered clinicopathologic models, there are few variants, whose biological profile is unknown or not elicited. Among these types, unicystic ameloblastoma is the least encountered variant of the ameloblastoma. Unicystic ameloblastoma refers to those cystic lesions that show clinical, radiographic, or gross features of a jaw cyst but on histologic examination show a typical ameloblastomatous epithelium lining the cyst cavity, with or without luminal and/or mural tumor proliferation. Unicystic ameloblastoma is a less encountered variant of the ameloblastoma and is believed to be less aggressive. As this tumor shows considerable similarities with dentigerous cysts, both clinically and radiographically, the biologic behaviour of this tumor group was reviewed. Moreover, recurrence of unicystic ameloblastoma may be long delayed, and a long-term postoperative followup is essential for proper management of these patients. Here we are presenting a case of unicystic ameloblastoma in an 18-year-old female patient.


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