Long-Term Laboratory Evolution of a Genetic Life-History Trade-Off in Drosophila melanogaster. 1. The Role of Genotype-by-Environment Interaction

Evolution ◽  
1994 ◽  
Vol 48 (4) ◽  
pp. 1244 ◽  
Author(s):  
Armand M. Leroi ◽  
Adam K. Chippindale ◽  
Michael R. Rose
Keyword(s):  
Drosophila Melanogaster ◽  
Life History ◽  
Genotype By Environment Interaction ◽  
Environment Interaction ◽  
Laboratory Evolution ◽  
Trade Off ◽  
Genotype By Environment

Long-Term Laboratory Evolution of a Genetic Life-History Trade-Off in Drosophila melanogaster. 2. Stability of Genetic Correlations

Evolution ◽  
1994 ◽  
Vol 48 (4) ◽  
pp. 1258 ◽  
Author(s):  
Armand M. Leroi ◽  
W. Royal Chen ◽  
Michael R. Rose
Keyword(s):  
Drosophila Melanogaster ◽  
Life History ◽  
Genetic Correlations ◽  
Laboratory Evolution ◽  
Trade Off

scholarly journals LONG-TERM LABORATORY EVOLUTION OF A GENETIC LIFE-HISTORY TRADE-OFF INDROSOPHILA MELANOGASTER. 2. STABILITY OF GENETIC CORRELATIONS

Evolution ◽  
1994 ◽  
Vol 48 (4) ◽  
pp. 1258-1268 ◽  
Author(s):  
Armand M. Leroi ◽  
W. Royal Chen ◽  
Michael R. Rose
Keyword(s):  
Life History ◽  
Genetic Correlations ◽  
Laboratory Evolution ◽  
Trade Off

scholarly journals Response of Regulatory Genetic Variation in Gene Expression to Environmental Change in Drosophila melanogaster

2020 ◽  
Author(s):  
Wen Huang ◽  
Mary Anna Carbone ◽  
Richard F. Lyman ◽  
Robert H. H. Anholt ◽  
Trudy F. C. Mackay
Keyword(s):  
Gene Expression ◽  
Drosophila Melanogaster ◽  
Genetic Architecture ◽  
Genetic Variance ◽  
Network Connectivity ◽  
Genotype By Environment Interaction ◽  
Stabilizing Selection ◽  
Environment Interaction ◽  
Genotype By Environment ◽  
Phenotypic Responses

AbstractThe genetics of phenotypic responses to changing environments remains elusive. Using whole genome quantitative gene expression as a model, we studied how the genetic architecture of regulatory variation in gene expression changed in a population of fully sequenced inbred Drosophila melanogaster strains when flies developed at different environments (25 °C and 18 °C). We found a substantial fraction of the transcriptome exhibited genotype by environment interaction, implicating environmentally plastic genetic architecture of gene expression. Genetic variance in expression increased at 18 °C relative to 25 °C for most genes that had a change in genetic variance. Although the majority of expression quantitative trait loci (eQTLs) for the gene expression traits in the two environments were shared and had similar effects, analysis of the environment-specific eQTLs revealed enrichment of binding sites for two transcription factors. Finally, although genotype by environment interaction in gene expression could potentially disrupt genetic networks, the co-expression networks were highly conserved across environments. Genes with higher network connectivity were under stronger stabilizing selection, suggesting that stabilizing selection on expression plays an important role in promoting network robustness.

CONDITION, GENOTYPE-BY-ENVIRONMENT INTERACTION, AND CORRELATIONAL SELECTION IN LIZARD LIFE-HISTORY MORPHS

Evolution ◽  
2001 ◽  
Vol 55 (10) ◽  
pp. 2053-2069 ◽  
Author(s):  
Erik Svensson ◽  
Barry Sinervo ◽  
Tosha Comendant
Keyword(s):  
Life History ◽  
Genotype By Environment Interaction ◽  
Environment Interaction ◽  
Genotype By Environment ◽  
Correlational Selection

scholarly journals Genotype by environment interaction for gene expression in Drosophila melanogaster

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Wen Huang ◽  
Mary Anna Carbone ◽  
Richard F. Lyman ◽  
Robert R. H. Anholt ◽  
Trudy F. C. Mackay
Keyword(s):  
Gene Expression ◽  
Drosophila Melanogaster ◽  
Genetic Architecture ◽  
Genetic Variance ◽  
Network Connectivity ◽  
Genotype By Environment Interaction ◽  
Stabilizing Selection ◽  
Environment Interaction ◽  
Genotype By Environment ◽  
Phenotypic Responses

Abstract The genetics of phenotypic responses to changing environments remains elusive. Using whole-genome quantitative gene expression as a model, here we study how the genetic architecture of regulatory variation in gene expression changed in a population of fully sequenced inbred Drosophila melanogaster strains when flies developed in different environments (25 °C and 18 °C). We find a substantial fraction of the transcriptome exhibited genotype by environment interaction, implicating environmentally plastic genetic architecture of gene expression. Genetic variance in expression increases at 18 °C relative to 25 °C for most genes that have a change in genetic variance. Although the majority of expression quantitative trait loci (eQTLs) for the gene expression traits in the two environments are shared and have similar effects, analysis of the environment-specific eQTLs reveals enrichment of binding sites for two transcription factors. Finally, although genotype by environment interaction in gene expression could potentially disrupt genetic networks, the co-expression networks are highly conserved across environments. Genes with higher network connectivity are under stronger stabilizing selection, suggesting that stabilizing selection on expression plays an important role in promoting network robustness.

Genotype-by-environment interaction analysis for grain yield of barley genotypes under dryland conditions and the role of monthly rainfall

2021 ◽  
Vol 245 ◽  
pp. 106665
Author(s):  
Farhad Ahakpaz ◽  
Hossein Abdi ◽  
Elyas Neyestani ◽  
Ali Hesami ◽  
Behrouz Mohammadi ◽  
...  
Keyword(s):  
Grain Yield ◽  
Interaction Analysis ◽  
Genotype By Environment Interaction ◽  
Monthly Rainfall ◽  
Environment Interaction ◽  
Genotype By Environment ◽  
Barley Genotypes

scholarly journals G × E interaction and neurodevelopment II. Focus on adversities in paediatric depression: the moderating role of serotonin transporter

2012 ◽  
Vol 22 (1) ◽  
pp. 21-28 ◽  
Author(s):  
M. Bellani ◽  
M. Nobile ◽  
V. Bianchi ◽  
J. van Os ◽  
P. Brambilla
Keyword(s):  
Serotonin Transporter ◽  
Internalizing Symptoms ◽  
Developmental Psychopathology ◽  
Genotype By Environment Interaction ◽  
Childhood And Adolescence ◽  
Environment Interaction ◽  
Genotype By Environment ◽  
Moderating Role ◽  
Over Time

In a short series of articles, we will review the evidence for genotype by environment interaction (G × E) in developmental psychopathology. We will focus specifically on the characteristics of types of exposure assessed with respect to both their methods and findings. This article aims to review the studies exploring the moderating role of serotonin transporter on the effect of environmental adversities over time, particularly during childhood and adolescence, which is when level of internalizing symptoms and prevalence of mood disorders change substantially. Environmental adversities will not include abuse and maltreatment that have been reviewed before (see Bellani et al. 2012) and child's broader social ecology that will be reviewed in the next section.

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