scholarly journals Effects of Transdermal Tulobuterol in Pediatric Asthma Patients on Long-Term Leukotriene Receptor Antagonist Therapy: Results of a Randomized, Open-Label, Multicenter Clinical Trial in Japanese Children Aged 4–12 Years

2013 ◽  
Vol 62 (1) ◽  
pp. 37-43 ◽  
Author(s):  
Toshio Katsunuma ◽  
Takao Fujisawa ◽  
Nagao Mizuho ◽  
Akasawa Akira ◽  
Ichiro Nomura ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Receptor Antagonist ◽  
Multicenter Clinical Trial ◽  
Leukotriene Receptor Antagonist ◽  
Japanese Children ◽  
Open Label ◽  
Antagonist Therapy ◽  
Asthma Patients ◽  
Leukotriene Receptor

The Position of Pranlukast, a Cysteinyl Leukotriene Receptor Antagonist, in the Long-Term Treatment of Asthma

Respiration ◽  
2004 ◽  
Vol 71 (3) ◽  
pp. 225-232 ◽  
Author(s):  
Yasushi Obase ◽  
Terufumi Shimoda ◽  
Hiroto Matsuse ◽  
Yuki Kondo ◽  
Ikuko Machida ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Term Treatment ◽  
Leukotriene Receptor Antagonist ◽  
Cysteinyl Leukotriene ◽  
Long Term Treatment ◽  
Leukotriene Receptor ◽  
Cysteinyl Leukotriene Receptor

scholarly journals Successful management of refractory cough with the leukotriene receptor antagonist zafirlukast in a dog with chronic bronchitis: a case report

2018 ◽  
Vol 63 (No. 4) ◽  
pp. 181-186
Author(s):  
IH Yoon ◽  
HJ Han ◽  
JH Kim
Keyword(s):  
Case Report ◽  
Receptor Antagonist ◽  
Chronic Bronchitis ◽  
Imaging Findings ◽  
Leukotriene Receptor Antagonist ◽  
Successful Management ◽  
History Of ◽  
Leukotriene Receptor ◽  
Term Management

A 7-year-old spayed female Pomeranian dog was evaluated for a 6-month history of intractable coughing and dyspnoea. The cough was unresponsive to antibiotics and a bronchodilator medication prescribed by the previous animal hospital. No abnormalities were identified on the blood work, echocardiography and radiography. However, computed tomography revealed mild bronchiectasia. Based on the history, physical examination and non-specific diagnostic imaging findings, the dog was diagnosed with chronic bronchitis. The cough failed to resolve, despite an attempt to manage it with prednisolone, theophylline, codeine and N-acetylcysteine. With the owner’s consent, we stopped all previous medications and finally tried the leukotriene receptor antagonist zafirlukast. The cough progressively improved and had mostly resolved four weeks after starting the administration of zafirlukast. The dog remained in complete remission without recurrence for seven months. This case report is the first to describe the successful long-term management of chronic cough with zafirlukast in a dog.

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