Efficacy and Safety of Mirogabalin (DS-5565) for the Treatment of Diabetic Peripheral Neuropathic Pain: A Randomized, Double-Blind, Placebo- and Active Comparator–Controlled, Adaptive Proof-of-Concept Phase 2 Study

Aaron Vinik; Julio Rosenstock; Uma Sharma; Karen Feins; Ching Hsu; Domenico Merante

doi:10.2337/dc14-1044

Efficacy and Safety of Mirogabalin (DS-5565) for the Treatment of Diabetic Peripheral Neuropathic Pain: A Randomized, Double-Blind, Placebo- and Active Comparator–Controlled, Adaptive Proof-of-Concept Phase 2 Study

Diabetes Care ◽

10.2337/dc14-1044 ◽

2014 ◽

Vol 37 (12) ◽

pp. 3253-3261 ◽

Cited By ~ 43

Author(s):

Aaron Vinik ◽

Julio Rosenstock ◽

Uma Sharma ◽

Karen Feins ◽

Ching Hsu ◽

...

Keyword(s):

Neuropathic Pain ◽

Phase 2 ◽

Proof Of Concept ◽

Efficacy And Safety ◽

Double Blind ◽

Peripheral Neuropathic Pain ◽

Double Blind Placebo ◽

Active Comparator ◽

Phase 2 Study

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Faculty Opinions recommendation of Efficacy and safety of regorafenib in adult patients with metastatic osteosarcoma: a non-comparative, randomised, double-blind, placebo-controlled, phase 2 study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.734506216.793579336 ◽

2020 ◽

Author(s):

Nathalie Gaspar

Keyword(s):

Adult Patients ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Metastatic Osteosarcoma ◽

Phase 2 Study

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SAT0110 Efficacy and Safety of Pateclizumab (Anti-Lymphotoxin-Alpha) in Dmard-Ir Patients: Results of a Randomized, Double-Blind, Placebo-Controlled Head-To-Head Phase 2 Study with Adalimumab

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2013-eular.1836 ◽

2013 ◽

Vol 72 (Suppl 3) ◽

pp. A617.2-A618

Author(s):

W. Kennedy ◽

P. Horn ◽

Z. Su ◽

K. Basu ◽

A. Herman ◽

...

Keyword(s):

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 2 Study ◽

Lymphotoxin Alpha

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Faculty Opinions recommendation of Risankizumab, an IL-23 inhibitor, for ankylosing spondylitis: results of a randomised, double-blind, placebo-controlled, proof-of-concept, dose-finding phase 2 study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.733519001.793576228 ◽

2020 ◽

Author(s):

Pedro Machado

Keyword(s):

Ankylosing Spondylitis ◽

Dose Finding ◽

Phase 2 ◽

Proof Of Concept ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 2 Study

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OP0047 A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Proof-Of-Concept Study to Evaluate the Efficacy and Safety of Sirukumab in Patients with Active Lupus Nephritis

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2014-eular.3974 ◽

2014 ◽

Vol 73 (Suppl 2) ◽

pp. 78.2-78 ◽

Cited By ~ 7

Author(s):

R. van Vollenhoven ◽

C. Aranow ◽

B. Rovin ◽

C. Wagner ◽

B. Zhou ◽

...

Keyword(s):

Lupus Nephritis ◽

Phase 2 ◽

Proof Of Concept ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Concept Study ◽

Active Lupus Nephritis ◽

Active Lupus

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Efficacy and Safety of E6011, an Anti-Fractalkine Monoclonal Antibody, in Active Rheumatoid Arthritis Patients with Inadequate Response to Methotrexate: Results of a Randomized, Double-Blind, Placebo-Controlled Phase 2 Study

SSRN Electronic Journal ◽

10.2139/ssrn.3523879 ◽

2020 ◽

Author(s):

Yoshiya Tanaka ◽

Tsutomu Takeuchi ◽

Hisashi Yamanaka ◽

Toshihiro Nanki ◽

Hisanori Umehara ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Monoclonal Antibody ◽

Active Rheumatoid Arthritis ◽

Inadequate Response ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 2 Study

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Faculty Opinions recommendation of A randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of ABT-594 in patients with diabetic peripheral neuropathic pain.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1166055.626955 ◽

2009 ◽

Author(s):

Nanna Finnerup

Keyword(s):

Neuropathic Pain ◽

Controlled Trial ◽

Efficacy And Safety ◽

Double Blind ◽

Peripheral Neuropathic Pain ◽

Double Blind Placebo

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Double-blind, placebo-controlled, randomized, phase 2 study to evaluate the efficacy and safety of maintenance therapy with anti-TA-MUC1 monoclonal antibody PankoMab after chemotherapy in patients with recurrent epithelial ovarian carcinoma.

Journal of Clinical Oncology ◽

10.1200/jco.2014.32.15_suppl.tps5622 ◽

2014 ◽

Vol 32 (15_suppl) ◽

pp. TPS5622-TPS5622

Author(s):

Jonathan A. Ledermann ◽

Ingo von Broen ◽

Frank Zimmermann ◽

Johannes Nippgen ◽

Steffen Goletz

Keyword(s):

Monoclonal Antibody ◽

Maintenance Therapy ◽

Ovarian Carcinoma ◽

Epithelial Ovarian Carcinoma ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 2 Study ◽

Randomized Phase 2

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A randomized, double-blind, placebo-controlled phase 2 study evaluating the efficacy and safety of romiplostim treatment of patients with low or intermediate-1 risk myelodysplastic syndrome receiving lenalidomide

Journal of Hematology & Oncology ◽

10.1186/1756-8722-5-71 ◽

2012 ◽

Vol 5 (1) ◽

Cited By ~ 39

Author(s):

Eunice S Wang ◽

Roger M Lyons ◽

Richard A Larson ◽

Sunil Gandhi ◽

Delong Liu ◽

...

Keyword(s):

Myelodysplastic Syndrome ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 2 Study

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Efficacy and Safety of E6011, an Anti‐Fractalkine Monoclonal Antibody, in Active Rheumatoid Arthritis Patients with Inadequate Response to Methotrexate: Results of a Randomized, Double‐blind, Placebo‐controlled Phase 2 study

Arthritis & Rheumatology ◽

10.1002/art.41555 ◽

2020 ◽

Author(s):

Yoshiya Tanaka ◽

Tsutomu Takeuchi ◽

Hisashi Yamanaka ◽

Toshihiro Nanki ◽

Hisanori Umehara ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Monoclonal Antibody ◽

Active Rheumatoid Arthritis ◽

Inadequate Response ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 2 Study

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1023-96 A randomized double-blind placebo-controlled phase 2 study on the efficacy and safety of fasudil in patients with stable angina

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(04)91080-7 ◽

2004 ◽

Vol 43 (5) ◽

pp. A254

Author(s):

Ralph M Vicari ◽

Bernard Chaitman ◽

Deborah Keefe ◽

William B Smith ◽

Steven G Chrysant ◽

...

Keyword(s):

Stable Angina ◽

Phase 2 ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Phase 2 Study

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