scholarly journals A Case of Synchronous Double Cancers Composed of Advanced Gallbladder Cancer and Early Bile Duct Cancer for which Radical Operation was Performed.

2007 ◽  
Vol 56 (3) ◽  
pp. 77-83 ◽  
Author(s):  
Hidefumi KUBO ◽  
Shinsuke KANEKIYO ◽  
Yusaku WATANABE ◽  
Kosuke TADA ◽  
Hiroyasu HASEGAWA ◽  
...  
Keyword(s):  
Bile Duct ◽  
Gallbladder Cancer ◽  
Bile Duct Cancer ◽  
Radical Operation ◽  
Double Cancers ◽  
Duct Cancer ◽  
Advanced Gallbladder Cancer

scholarly journals A Case of Lower Bile Duct Cancer Associated with Pancreaticobiliary Maljunction without Bile Duct Dilation after Operation of a Gallbladder Cancer

2007 ◽  
Vol 40 (9) ◽  
pp. 1623-1629 ◽  
Author(s):  
Michihiro Ishida ◽  
Takefumi Niguma ◽  
Takurou Yukawa ◽  
Tetsushige Mimura ◽  
Masanobu Tsutsui
Keyword(s):  
Bile Duct ◽  
Gallbladder Cancer ◽  
Bile Duct Cancer ◽  
Pancreaticobiliary Maljunction ◽  
Duct Cancer

scholarly journals Smoking, Alcohol, and Biliary Tract Cancer Risk: A Pooling Project of 26 Prospective Studies

2019 ◽  
Vol 111 (12) ◽  
pp. 1263-1278 ◽  
Author(s):  
Emma E McGee ◽  
Sarah S Jackson ◽  
Jessica L Petrick ◽  
Alison L Van Dyke ◽  
Hans-Olov Adami ◽  
...  
Keyword(s):  
Bile Duct ◽  
Alcohol Consumption ◽  
Gallbladder Cancer ◽  
Biliary Tract ◽  
Bile Duct Cancer ◽  
Extrahepatic Bile Duct ◽  
Intrahepatic Bile Duct ◽  
Ampulla Of Vater ◽  
Biliary Tract Cancers ◽  
Duct Cancer

Abstract Background Tobacco and alcohol are well-established risk factors for numerous cancers, yet their relationship to biliary tract cancers remains unclear. Methods We pooled data from 26 prospective studies to evaluate associations of cigarette smoking and alcohol consumption with biliary tract cancer risk. Study-specific hazard ratios (HRs) and 95% confidence intervals (CIs) for associations with smoking and alcohol consumption were calculated. Random-effects meta-analysis produced summary estimates. All statistical tests were two-sided. Results Over a period of 38 369 156 person-years of follow-up, 1391 gallbladder, 758 intrahepatic bile duct, 1208 extrahepatic bile duct, and 623 ampulla of Vater cancer cases were identified. Ever, former, and current smoking were associated with increased extrahepatic bile duct and ampulla of Vater cancers risk (eg, current vs never smokers HR = 1.69, 95% CI = 1.34 to 2.13 and 2.22, 95% CI = 1.69 to 2.92, respectively), with dose-response effects for smoking pack-years, duration, and intensity (all Ptrend < .01). Current smoking and smoking intensity were also associated with intrahepatic bile duct cancer (eg, >40 cigarettes per day vs never smokers HR = 2.15, 95 % CI = 1.15 to 4.00; Ptrend = .001). No convincing association was observed between smoking and gallbladder cancer. Alcohol consumption was only associated with intrahepatic bile duct cancer, with increased risk for individuals consuming five or more vs zero drinks per day (HR = 2.35, 95%CI = 1.46 to 3.78; Ptrend = .04). There was evidence of statistical heterogeneity among several cancer sites, particularly between gallbladder cancer and the other biliary tract cancers. Conclusions Smoking appears to increase the risk of developing all biliary tract cancers except gallbladder cancer. Alcohol may increase the risk of intrahepatic bile duct cancer. Findings highlight etiologic heterogeneity across the biliary tract.

scholarly journals A CASE REPORT OF METACHRONOUS TRIPLE CANCER-(GASTRIC CANCER, GALLBLADDER CANCER, COMMON BILE DUCT CANCER)-

1997 ◽  
Vol 58 (12) ◽  
pp. 3015-3019
Author(s):  
Masatoshi ISHIZAKI ◽  
Norio AKIYAMA ◽  
Hiroyuki KATO ◽  
Hajime SASAMOTO ◽  
Hidenobu OSAWA ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Case Report ◽  
Bile Duct ◽  
Common Bile Duct ◽  
Gallbladder Cancer ◽  
Bile Duct Cancer ◽  
Common Bile Duct Cancer ◽  
Duct Cancer ◽  
Triple Cancer

Is extended hemihepatectomy plus pancreaticoduodenectomy justified for advanced bile duct cancer and gallbladder cancer?

Surgery ◽  
2013 ◽  
Vol 153 (6) ◽  
pp. 794-800 ◽  
Author(s):  
Yoshihiro Sakamoto ◽  
Satoshi Nara ◽  
Yoji Kishi ◽  
Minoru Esaki ◽  
Kazuaki Shimada ◽  
...  
Keyword(s):  
Bile Duct ◽  
Gallbladder Cancer ◽  
Bile Duct Cancer ◽  
Duct Cancer

scholarly journals Increased prevalence of pancreaticobiliary maljunction in biliary malignancies

2019 ◽  
Vol 108 (4) ◽  
pp. 285-290 ◽  
Author(s):  
I. Hyvärinen ◽  
M. Hukkinen ◽  
R. Kivisaari ◽  
H. Parviainen ◽  
A. Nordin ◽  
...  
Keyword(s):  
Bile Duct ◽  
Magnetic Resonance ◽  
Gallbladder Cancer ◽  
Bile Duct Cancer ◽  
Magnetic Resonance Cholangiopancreatography ◽  
Pancreaticobiliary Maljunction ◽  
Age At Diagnosis ◽  
Extrahepatic Bile Duct Cancer ◽  
Duct Cancer ◽  
Biliary Malignancies

Aim: The incidence of pancreaticobiliary maljunction is thought to approximate 1:100,000 within Western populations. We aimed to study the significance of pancreaticobiliary maljunction in biliary tract malignancies. Methods: Medical records and magnetic resonance cholangiopancreatography images of 252 consecutive patients treated for biliary malignancies during 2005–2016 were reviewed. Patients with other known risk factors for biliary cancers (n = 27) were excluded. A common pancreaticobiliary channel measuring ⩾10 mm outside the duodenal wall was defined as pancreaticobiliary maljunction. Main Results: Of the 225 patients, a reliably interpretable preoperative magnetic resonance cholangiopancreatography was available for 73 (32%). Sex (47% vs 57% females) and age at diagnosis (67 vs 66 years) were similar among patients with or without an magnetic resonance cholangiopancreatography (p = ns for both). In magnetic resonance cholangiopancreatography, a pancreaticobiliary maljunction with a median length of 20 mm (range 10–23 mm) was identified in four patients (5.5%, 95% confidence interval 1.6–14), while none had evident accompanying biliary tree dilatation. Pancreaticobiliary maljunction patients were significantly more often females (100% vs 43%, p = 0.043), less likely to have intrahepatic bile duct cancer (0% vs 65%, p = 0.019) while more likely to have gallbladder cancer (75% vs 22%, p = 0.044) compared to the others. Age at diagnosis (66 vs 67 years, p = 0.898), extrahepatic bile duct cancer incidence (25% vs 13%, p = 0.453), and survival status at last follow-up (50% vs 42% alive, p = 1.000) were comparable between the subgroups. Conclusion: The prevalence of pancreaticobiliary maljunction is substantially higher in adults with biliary malignancies than one would expect based on its incidence, reinforcing the etiologic role of pancreaticobiliary maljunction especially in females with gallbladder cancer.

Hepatopancreatoduodenectomy: its suitability for bile duct cancer versus gallbladder cancer

2007 ◽  
Vol 14 (2) ◽  
pp. 142-148 ◽  
Author(s):  
Yuji Kaneoka ◽  
Akihiro Yamaguchi ◽  
Masatoshi Isogai
Keyword(s):  
Bile Duct ◽  
Gallbladder Cancer ◽  
Bile Duct Cancer ◽  
Duct Cancer

scholarly journals A Surgical Case of Synchronous Double Primary Cancers of the Bile Duct and Pancreas

2017 ◽  
Author(s):  
Kazuhiro Suzumura ◽  
Yasukane Asano ◽  
Hisashi Kosaka ◽  
Hideaki Sueoka ◽  
Tadamichi Hirano ◽  
...  
Keyword(s):  
Bile Duct ◽  
Pancreatic Duct ◽  
Bile Duct Cancer ◽  
Main Pancreatic Duct ◽  
Histopathological Examination ◽  
Tubular Adenocarcinoma ◽  
Pancreatic Body ◽  
Double Cancers ◽  
Duct Cancer ◽  
Pancreatic Body Cancer

Abstract A 54-year-old female was seen at another hospital because of jaundice. CT showed an unclear boundary and a poorly enhanced mass lesion in the pancreatic body, measuring 28 mm in diameter. MRCP showed stenosis of the lower bile duct and the main pancreatic duct in the pancreatic body and slight dilatation of the main pancreatic duct in the pancreatic tail. According to these findings, the preoperative diagnosis was synchronous double cancers of primary lower bile duct cancer and pancreatic body cancer. We performed pylorus-preserving pancreaticoduodenectomy with splenic artery and vein resection. A histopathological examination revealed that the lower bile duct tumor was moderately differentiated tubular adenocarcinoma, and the pancreatic body tumor was moderately differentiated tubular adenocarcinoma. These two tumors showed no histopathological continuity. According to these pathological findings, we diagnosed the patient with synchronous double cancers of primary lower bile duct cancer and pancreatic body cancer. The patient was discharged from the hospital on the 48th day after surgery. However, she died of multiple organ failure due to cancer recurrence 22 months after surgery.

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