Integrating Improved U-Net and Continuous Maximum Flow Algorithm for 3D Brain Tumor Image Segmentation

2020 ◽  
Vol 64 (4) ◽  
pp. 40412-1-40412-11
Author(s):  
Kexin Bai ◽  
Qiang Li ◽  
Ching-Hsin Wang
Keyword(s):  
Brain Tumor ◽  
Data Augmentation ◽  
A Priori ◽  
Class Imbalance ◽  
Maximum Flow ◽  
Magnetic Resonance Images ◽  
Tumor Segmentation ◽  
Similarity Coefficients ◽  
Segmentation Algorithms ◽  
Flow Algorithm

Abstract To address the issues of the relatively small size of brain tumor image datasets, severe class imbalance, and low precision in existing segmentation algorithms for brain tumor images, this study proposes a two-stage segmentation algorithm integrating convolutional neural networks (CNNs) and conventional methods. Four modalities of the original magnetic resonance images were first preprocessed separately. Next, preliminary segmentation was performed using an improved U-Net CNN containing deep monitoring, residual structures, dense connection structures, and dense skip connections. The authors adopted a multiclass Dice loss function to deal with class imbalance and successfully prevented overfitting using data augmentation. The preliminary segmentation results subsequently served as the a priori knowledge for a continuous maximum flow algorithm for fine segmentation of target edges. Experiments revealed that the mean Dice similarity coefficients of the proposed algorithm in whole tumor, tumor core, and enhancing tumor segmentation were 0.9072, 0.8578, and 0.7837, respectively. The proposed algorithm presents higher accuracy and better stability in comparison with some of the more advanced segmentation algorithms for brain tumor images.

scholarly journals Learning rich features with hybrid loss for brain tumor segmentation

2021 ◽  
Vol 21 (S2) ◽  
Author(s):  
Daobin Huang ◽  
Minghui Wang ◽  
Ling Zhang ◽  
Haichun Li ◽  
Minquan Ye ◽  
...  
Keyword(s):  
Feature Extraction ◽  
Brain Tumor ◽  
Class Imbalance ◽  
Feature Representation ◽  
Loss Functions ◽  
Radiotherapy Planning ◽  
Tumor Segmentation ◽  
Brain Tumor Segmentation ◽  
Scale Feature ◽  
Multi Scale

Abstract Background Accurately segment the tumor region of MRI images is important for brain tumor diagnosis and radiotherapy planning. At present, manual segmentation is wildly adopted in clinical and there is a strong need for an automatic and objective system to alleviate the workload of radiologists. Methods We propose a parallel multi-scale feature fusing architecture to generate rich feature representation for accurate brain tumor segmentation. It comprises two parts: (1) Feature Extraction Network (FEN) for brain tumor feature extraction at different levels and (2) Multi-scale Feature Fusing Network (MSFFN) for merge all different scale features in a parallel manner. In addition, we use two hybrid loss functions to optimize the proposed network for the class imbalance issue. Results We validate our method on BRATS 2015, with 0.86, 0.73 and 0.61 in Dice for the three tumor regions (complete, core and enhancing), and the model parameter size is only 6.3 MB. Without any post-processing operations, our method still outperforms published state-of-the-arts methods on the segmentation results of complete tumor regions and obtains competitive performance in another two regions. Conclusions The proposed parallel structure can effectively fuse multi-level features to generate rich feature representation for high-resolution results. Moreover, the hybrid loss functions can alleviate the class imbalance issue and guide the training process. The proposed method can be used in other medical segmentation tasks.

scholarly journals Improving Brain Tumor Segmentation with Data Augmentation Strategies

2021 ◽  
Author(s):  
Radhika Malhotra ◽  
Jasleen Saini ◽  
Barjinder Singh Saini ◽  
Savita Gupta
Keyword(s):  
Brain Tumor ◽  
Data Augmentation ◽  
Large Data ◽  
Training Data ◽  
Tumor Segmentation ◽  
Biomedical Image Processing ◽  
Brain Tumor Segmentation ◽  
Biomedical Image ◽  
Augmentation Strategies ◽  
Unseen Data

In the past decade, there has been a remarkable evolution of convolutional neural networks (CNN) for biomedical image processing. These improvements are inculcated in the basic deep learning-based models for computer-aided detection and prognosis of various ailments. But implementation of these CNN based networks is highly dependent on large data in case of supervised learning processes. This is needed to tackle overfitting issues which is a major concern in supervised techniques. Overfitting refers to the phenomenon when a network starts learning specific patterns of the input such that it fits well on the training data but leads to poor generalization abilities on unseen data. The accessibility of enormous quantity of data limits the field of medical domain research. This paper focuses on utility of data augmentation (DA) techniques, which is a well-recognized solution to the problem of limited data. The experiments were performed on the Brain Tumor Segmentation (BraTS) dataset which is available online. The results signify that different DA approaches have upgraded the accuracies for segmenting brain tumor boundaries using CNN based model.

scholarly journals Brain Tumor Classification of MRI Images Using Deep Convolutional Neural Network

2021 ◽  
Vol 38 (4) ◽  
pp. 1171-1179
Author(s):  
Swaraja Kuraparthi ◽  
Madhavi K. Reddy ◽  
C.N. Sujatha ◽  
Himabindu Valiveti ◽  
Chaitanya Duggineni ◽  
...  
Keyword(s):  
Neural Network ◽  
Brain Tumor ◽  
Magnetic Resonance ◽  
Data Augmentation ◽  
Magnetic Resonance Images ◽  
Tumor Classification ◽  
Support Vector ◽  
Svm Classifier ◽  
Tumor Type

Manual tumor diagnosis from magnetic resonance images (MRIs) is a time-consuming procedure that may lead to human errors and may lead to false detection and classification of the tumor type. Therefore, to automatize the complex medical processes, a deep learning framework is proposed for brain tumor classification to ease the task of doctors for medical diagnosis. Publicly available datasets such as Kaggle and Brats are used for the analysis of brain images. The proposed model is implemented on three pre-trained Deep Convolution Neural Network architectures (DCNN) such as AlexNet, VGG16, and ResNet50. These architectures are the transfer learning methods used to extract the features from the pre-trained DCNN architecture, and the extracted features are classified by using the Support Vector Machine (SVM) classifier. Data augmentation methods are applied on Magnetic Resonance images (MRI) to avoid the network from overfitting. The proposed methodology achieves an overall accuracy of 98.28% and 97.87% without data augmentation and 99.0% and 98.86% with data augmentation for Kaggle and Brat's datasets, respectively. The Area Under Curve (AUC) for Receiver Operator Characteristic (ROC) is 0.9978 and 0.9850 for the same datasets. The result shows that ResNet50 performs best in the classification of brain tumors when compared with the other two networks.

scholarly journals Dense Hierarchical CNN – A Unified Approach for Brain Tumor Segmentation

2021 ◽  
Vol 35 (3) ◽  
pp. 223-233
Author(s):  
Roohi Sille ◽  
Tanupriya Choudhury ◽  
Piyush Chauhan ◽  
Durgansh Sharma
Keyword(s):  
Brain Tumor ◽  
Signal To Noise Ratio ◽  
Imaging Techniques ◽  
Tumor Segmentation ◽  
Neoplastic Tissue ◽  
Brain Tumor Segmentation ◽  
Brain Tumor Cells ◽  
Segmentation Algorithms ◽  
Heterogeneous Nature ◽  
The Brain

Brain tumor segmentation is an essential and challenging task because of the heterogeneous nature of neoplastic tissue in spatial and imaging techniques. Manual segmentation of the tumor in MRI images is prone to error and time-consuming tasks. An efficient segmentation mechanism is vital to the accurate classification and segmentation of tumorous cells. This study presents an efficient hierarchical clustering-based dense CNN approach for accurately classifying and segmenting the brain tumor cells in MRI images. The research focuses on improving the efficiency of the segmentation algorithms by considering the qualitative measures such as the dice score coefficient using quantitative parameters such as mean square error and peak signal to noise ratio. The experimental analysis states the efficacy and prominence of the proposed technique compared to other models are tabulated within the paper.

scholarly journals Emergence of Convolutional Neural Network in Future Medicine: Why and How. A Review on Brain Tumor Segmentation

2018 ◽  
Vol 24 (1) ◽  
pp. 43-53
Author(s):  
Behrouz Alizadeh Savareh ◽  
Hassan Emami ◽  
Mohamadreza Hajiabadi ◽  
Mahyar Ghafoori ◽  
Seyed Majid Azimi
Keyword(s):  
Neural Network ◽  
Image Processing ◽  
Brain Tumor ◽  
Convolutional Neural Network ◽  
Magnetic Resonance Images ◽  
Tumor Segmentation ◽  
Brain Tumor Segmentation ◽  
Manual Analysis ◽  
The Brain ◽  
Evaluation Parameters

Abstract Manual analysis of brain tumors magnetic resonance images is usually accompanied by some problem. Several techniques have been proposed for the brain tumor segmentation. This study will be focused on searching popular databases for related studies, theoretical and practical aspects of Convolutional Neural Network surveyed in brain tumor segmentation. Based on our findings, details about related studies including the datasets used, evaluation parameters, preferred architectures and complementary steps analyzed. Deep learning as a revolutionary idea in image processing, achieved brilliant results in brain tumor segmentation too. This can be continuing until the next revolutionary idea emerging.

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