scholarly journals Lessons from the Past: Methodological Issues Arising from Comparison of the Disease Burden of the Influenza A (H1N1) Pandemic 2009-10 and Seasonal Influenza 2010-2019 in the United States

2021 ◽  
Vol 7 (7) ◽  
Author(s):  
Koziol James A ◽  
Schnitzer Jan E
Keyword(s):  
United States ◽  
Influenza A ◽  
Disease Burden ◽  
Seasonal Influenza ◽  
The United States ◽  
H1n1 Pandemic ◽  
Methodological Issues ◽  
The Past ◽  
Influenza A H1n1

scholarly journals Lessons from the Past: Comparison of the Disease Burden of the Influenza A (H1N1) Pandemic 2009-10 and Seasonal Influenza 2010-2019 in the United States

2021 ◽  
Author(s):  
James A Koziol
Keyword(s):  
United States ◽  
Influenza A ◽  
Disease Burden ◽  
Seasonal Influenza ◽  
The United States ◽  
H1n1 Pandemic ◽  
Elderly Adults ◽  
The Past ◽  
Medical Visits ◽  
Influenza A H1n1

Abstract Background Annual influenza outbreaks constitute a major public health concern, both in the United States and worldwide. Comparisons of the health burdens of outbreaks might lead to the identification of specific at-risk populations, for whom public health resources should be marshaled appropriately and equitably. Methods We examined the disease burden of the 2009-10 influenza A (H1N1) pandemic relating to illnesses, medical visits, hospitalizations, and mortality, compared to influenza seasons 2010 to 2019, in the United States, as compiled by the Centers for Disease Control. Results With regard to seasonal influenza, rates of illnesses and medical visits were highest in infants aged 0–4 years, followed by adults aged 50–64 years. Rates of hospitalizations and deaths evinced a starkly different pattern, both dominated by elderly adults aged 65 and over. Youths aged 0 to 17 years were especially adversely affected by the H1N1 pandemic relative to hospitalizations and mortality compared to seasonal influenza; but curiously the opposite pattern was observed in elderly adults (aged 65 and older). Conclusions The disease burden of the 2009-10 influenza A pandemic was strikingly unlike that observed in the subsequent influenza seasons 2010 to 2019, in the United States: the past did not predict the future.

scholarly journals Narcolepsy and influenza A(H1N1) pandemic 2009 vaccination in the United States

Neurology ◽  
2014 ◽  
Vol 83 (20) ◽  
pp. 1823-1830 ◽  
Author(s):  
J. Duffy ◽  
E. Weintraub ◽  
C. Vellozzi ◽  
F. DeStefano ◽  
Keyword(s):  
United States ◽  
Influenza A ◽  
The United States ◽  
H1n1 Pandemic ◽  
Influenza A H1n1

scholarly journals Planning for the Control of Pandemic Influenza A (H1N1) in Los Angeles County and the United States

2011 ◽  
Vol 173 (10) ◽  
pp. 1121-1130 ◽  
Author(s):  
D. L. Chao ◽  
L. Matrajt ◽  
N. E. Basta ◽  
J. D. Sugimoto ◽  
B. Dean ◽  
...  
Keyword(s):  
United States ◽  
Los Angeles ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Los Angeles County ◽  
The United States ◽  
Influenza A H1n1

scholarly journals Household Transmission of 2009 Pandemic Influenza A (H1N1) Virus in the United States

2009 ◽  
Vol 361 (27) ◽  
pp. 2619-2627 ◽  
Author(s):  
Simon Cauchemez ◽  
Christl A. Donnelly ◽  
Carrie Reed ◽  
Azra C. Ghani ◽  
Christophe Fraser ◽  
...  
Keyword(s):  
United States ◽  
Pandemic Influenza ◽  
Influenza A ◽  
H1n1 Virus ◽  
The United States ◽  
Household Transmission ◽  
Influenza A H1n1

scholarly journals Epidemiology of 2009 Pandemic Influenza A (H1N1) Deaths in the United States, April-July 2009

2010 ◽  
Vol 52 (Supplement 1) ◽  
pp. S60-S68 ◽  
Author(s):  
A. L. Fowlkes ◽  
P. Arguin ◽  
M. S. Biggerstaff ◽  
J. Gindler ◽  
D. Blau ◽  
...  
Keyword(s):  
United States ◽  
Pandemic Influenza ◽  
Influenza A ◽  
The United States ◽  
Influenza A H1n1

scholarly journals Hospitalized Patients with 2009 Pandemic Influenza A (H1N1) Virus Infection in the United States—September–October 2009

2011 ◽  
Vol 52 (suppl_1) ◽  
pp. S50-S59 ◽  
Author(s):  
Jacek Skarbinski ◽  
Seema Jain ◽  
Anna Bramley ◽  
Esther J. Lee ◽  
Jean Huang ◽  
...  
Keyword(s):  
United States ◽  
Virus Infection ◽  
Pandemic Influenza ◽  
Influenza A ◽  
H1n1 Virus ◽  
The United States ◽  
Hospitalized Patients ◽  
Influenza A H1n1 ◽  
H1n1 Virus Infection

scholarly journals Identification and Epidemiology of Severe Respiratory Disease due to Novel Swine-Origin Influenza A (H1N1) Virus Infection in Alberta

2010 ◽  
Vol 21 (4) ◽  
pp. e151-e157
Author(s):  
George Zahariadis ◽  
Ari R Joffe ◽  
James Talbot ◽  
Albert deVilliers ◽  
Patricia Campbell ◽  
...  
Keyword(s):  
United States ◽  
Respiratory Infection ◽  
Influenza A ◽  
Respiratory Illness ◽  
The United States ◽  
Molecular Methods ◽  
Contact Tracing ◽  
Severe Respiratory Distress ◽  
Influenza A H1n1 ◽  
Severe Respiratory Infection

BACKGROUND: In March 2009, global surveillance started detecting cases of influenza-like illness in Mexico. By mid-April 2009, two pediatric patients were identified in the United States who were confirmed to be infected by a novel influenza A (H1N1) strain. The present article describes the first identified severe respiratory infection and the first death associated with pandemic H1N1 (pH1N1) in Canada.METHODS: Enhanced public health and laboratory surveillance for pH1N1 was implemented throughout Alberta on April 24, 2009. Respiratory specimens from all patients with a respiratory illness and travel history or those presenting with a severe respiratory infection requiring hospitalization underwent screening for respiratory viruses using molecular methods. For the first severe case identified and the first death due to pH1N1, histocompatibility leukocyte antigens were compared by molecular methods.RESULTS: The first death (a 39-year-old woman) occurred on April 28, 2009, and on May 1, 2009, a 10-year-old child presented with severe respiratory distress due to pH1N1. Both patients had no travel or contact with anyone who had travelled to Mexico; the cases were not linked. Histocompatibility antigen comparison of both patients did not identify any notable similarity. pH1N1 strains identified in Alberta did not differ from the Mexican strain.CONCLUSION: Rapid transmission of pH1N1 continued to occur in Alberta following the first death and the first severe respiratory infection in Canada, which were identified without any apparent connection to Mexico or the United States. Contact tracing follow-up suggested that oseltamivir may have prevented ongoing transmission of pH1N1.

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