scholarly journals Evaluation of Solid Focal Liver Lesions by Shear Wave Sonoelastography with FNAC Correlation

2020 ◽  
Vol 6 (2) ◽  
Author(s):  
Singla Ashu ◽  
TT Vishwanath ◽  
Das Sudha Kiran ◽  
Murthy Nagaraj ◽  
Patil Vikram ◽  
...  
Keyword(s):  
Shear Wave ◽  
Focal Liver Lesions ◽  
Liver Lesions

Shear Wave Dispersion Imaging for the Characterization of Focal Liver Lesions – A Pilot study

2021 ◽  
Author(s):  
Daniel Jesper ◽  
Steffen Fiedler ◽  
Daniel Klett ◽  
Maximilian J Waldner ◽  
Barbara Schellhaas ◽  
...  
Keyword(s):  
Shear Wave ◽  
Wave Dispersion ◽  
Liver Parenchyma ◽  
Benign Tumors ◽  
Focal Liver Lesions ◽  
Liver Lesions ◽  
Shear Wave Speed ◽  
Lower Shear ◽  
Malignant Lesions

Abstract Purpose Shear wave dispersion imaging is a novel ultrasound-based technique, which analyzes the speed of different shear wave components depending on their frequency. The dispersion of shear wave speed correlates with the viscosity of the liver parenchyma. The aim of this prospective study was to evaluate the use of shear wave dispersion imaging in focal liver lesions in the non-cirrhotic liver. Methods Patients with unclear focal liver lesions in B-mode ultrasound were prospectively assigned to shear wave dispersion imaging (m/s/kHz). Measurements were conducted within the lesion and in the liver parenchyma of the right liver lobe using an intercostal window. Histology and contrast-enhanced ultrasound served as the reference for the characterization of the lesions. Results Out of 46 patients included in this study, 24 had liver metastases and 22 had benign liver lesions. Benign lesions consisted mostly of hemangiomas (n=12) and focal nodular hyperplasia (n=8). Malignant lesions showed significantly lower shear wave dispersion (13.0±2.45 m/s/kHz) compared to benign tumors (15.2±2.74 m/s/kHz, p<0.01). In further subgroup analysis, the difference was significant for hemangiomas (15.32±2.42 m/s/kHz, p=0.04) but not for FNHs (14.98±3.36 m/s/kHz, p=0.38). The dispersion of reference liver parenchyma did not differ significantly between the groups (p=0.54). Conclusion The quantification of viscosity by shear wave dispersion is a new parameter for the characterization of focal liver lesions with higher dispersion values in hemangiomas and lower dispersion values in metastases. However, it cannot differentiate reliably between benign and malignant lesions.

Utility of point shear wave elastography in characterisation of focal liver lesions

2017 ◽  
Vol 12 (2) ◽  
pp. 201-207 ◽  
Author(s):  
Maha Hasab Allah ◽  
Rabab Maamoun Salama ◽  
Mohamad Saeed Marie ◽  
Ahmed Alsaeed Mandur ◽  
Heba Omar
Keyword(s):  
Shear Wave ◽  
Shear Wave Elastography ◽  
Focal Liver Lesions ◽  
Liver Lesions

Shear wave elastography-based ultrasomics: differentiating malignant from benign focal liver lesions

2020 ◽  
Author(s):  
Wei Wang ◽  
Jian-Chao Zhang ◽  
Wen-Shuo Tian ◽  
Li-Da Chen ◽  
Qiao Zheng ◽  
...  
Keyword(s):  
Shear Wave ◽  
Shear Wave Elastography ◽  
Focal Liver Lesions ◽  
Liver Lesions

Preliminary Clinical Experience with Shear Wave Dispersion Imaging for Liver Viscosity in Preoperative Diagnosis of Focal Liver Lesions

2020 ◽  
Vol 58 (09) ◽  
pp. 847-854
Author(s):  
Yi Dong ◽  
Yijie Qiu ◽  
Qi Zhang ◽  
Daohui Yang ◽  
Lingyun Yu ◽  
...  
Keyword(s):  
Shear Wave ◽  
Liver Tumors ◽  
Area Under The Curve ◽  
Wave Dispersion ◽  
Liver Parenchyma ◽  
Final Diagnosis ◽  
Focal Liver Lesions ◽  
Liver Lesions ◽  
Medical Systems ◽  
The Right

Abstract Background The aim of our study is to analyze viscosity characteristics of focal liver lesions (FLLs) and the diagnostic performance of shear wave dispersion (SWD) in differentiating benign and malignant FLLs. Methods Between January 2018 and April 2018, 58 consecutive patients (median age 57, age range 21–74 years, 37 males) with 58 FLLs located on the right lobe of liver were prospectively studied. The Aplio i900 series diagnostic ultrasound system (Canon Medical systems) equipped with a curvilinear PV1-475BX transducer (1–8 MHz) was used. SWD slope and viscosity measurements were expressed as mean ± standard deviation for both liver tumors and background liver parenchyma. Histopathological results after surgery were regarded as the gold standard for diagnosis. Results Final diagnosis included 40 cases of malignant and 18 cases of benign FLLs. The mean viscosity value were 14.78 ± 1.86 m/s/kHz for hepatocellular carcinoma (n = 30), 14.81 ± 2.35 m/s/kHz for liver metastasis lesions (n = 10), 13.23 ± 1.31 m/s/kHz for hemangioma (n = 13), and 13.67 ± 2.72 m/s/kHz for focal nodular hyperplasia (n = 5). Malignant FLLs showed higher mean viscosity values (14.79 ± 3.15 m/s/KHz) than benign FLLs (13.36 ± 2.76 m/s/KHz) (p < 0.05). The best performing cut-off value of lesion viscosity was 13.15 m/s/kHz (sensitivity 83.3 %; specificity 56.5 %; area under the curve (AUC) 0.71) for malignancy) (p < 0.05). Conclusions The analysis of SWD slope and liver viscosity parameters provide additional viscoelastic information about FLLs before operation.

scholarly journals Value of shear wave elastography with maximal elasticity in differentiating benign and malignant solid focal liver lesions

2020 ◽  
Vol 26 (46) ◽  
pp. 7416-7424
Author(s):  
Hui-Ping Zhang ◽  
Ji-Ying Gu ◽  
Min Bai ◽  
Fan Li ◽  
Yu-Qing Zhou ◽  
...  
Keyword(s):  
Shear Wave ◽  
Shear Wave Elastography ◽  
Focal Liver Lesions ◽  
Liver Lesions

Intraoperative Shear Wave Elastography vs. Contrast-Enhanced Ultrasound for the Characterization and Differentiation of Focal Liver Lesions to Optimize Liver Tumor Surgery

2018 ◽  
Vol 40 (02) ◽  
pp. 205-211 ◽  
Author(s):  
Natascha da Silva ◽  
Matthias Hornung ◽  
Lukas Beyer ◽  
Christina Hackl ◽  
Stefan Brunner ◽  
...  
Keyword(s):  
Shear Wave ◽  
Liver Surgery ◽  
Sulfur Hexafluoride ◽  
Tumor Resection ◽  
Shear Wave Elastography ◽  
Focal Liver Lesions ◽  
Liver Lesions ◽  
Contrast Enhanced Ultrasound ◽  
Shear Wave Speed ◽  
Contrast Enhanced

Abstract Purpose Assessment of intraoperative quantitative shear wave elastography (SWE) and contrast-enhanced ultrasound (CEUS) for the characterization of focal liver lesions (FLLs) during liver surgery using postoperative histopathological results as the gold standard. Materials and Methods US data of 79 consecutive patients with 98 FLLs who underwent liver surgery between 08/2015 – 06/2017 were prospectively acquired and retrospectively analyzed. Multifrequency linear/T-shaped probes (6 – 9 MHz) were used to store cine loops of at least 5 s and images of B-mode, SWE and CEUS. The first CEUS loop was continuously documented over 1 min. in each case. Quantitative SWE analysis of FLLs was performed by placing 5 regions of interest to measure shear wave speed (m/s) and stiffness (kPa). CEUS was evaluated during the arterial, portal venous and late phase after i. v. bolus injections of 2.4 – 10 ml sulfur hexafluoride microbubbles. Postoperative histopathology after tumor resection or intraoperative biopsy was obtained to confirm findings of SWE and CEUS. Results Of 98 FLLs in 79 patients (mean age: 58 years sd ± 12y) 88 were malignant and 10 were benign ranging from 0.69 to 15.2 cm in size (mean: 2.8 cm, sd ± 2.25 cm). SWE characterized 73/88 FLLs correctly as malignant and 7/10 as benign using a cut-off value of 2.5 m/s/21.3 kPa (p < 0.0005). The sensitivity was 83 %, specificity 70 %, accuracy 82 %. CEUS could correctly identify 86/88 malignant and 8/10 benign FLLs. The sensitivity was 98 %, specificity 80 %, accuracy 96 %. SWE could correctly identify 2 malignant FLLs which CEUS falsely characterized as benign. Conclusion Intraoperative CEUS and SWE are excellent tools for the highly accurate visualization, characterization and malignancy assessment of hepatic tumors during liver surgery.

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