Heart rate and other risk factors in outpatients with stable coronary artery disease in Latvia

Heart rate and other risk factors in outpatients with stable coronary artery disease in Latvia The aim of the study was to characterise coronary artery disease (CAD) outpatients in Latvia by risk factors (RF) including heart rate (HR), physical examination data, clinical data and treatment. Twelve practitioners had each examined and questioned 6 to 12 patients with established CAD (n = 120). The most frequent cardiovascular (CV) RF and co-morbidity were dyslipidemia (94.2%) and hypertension (78.3%), respectively. Prevalence of increased resting HR (≥70 bpm) was 35.9% and 33.6%, when measured by pulse palpation and electrocardiography, respectively. Regarding other RFs, prevalence of treated but insufficiently controlled blood pressure 140/90 mmHg, total cholesterol 1 > 5 mmol/l and triglycerides > 1.7 mmol/l was 25.8%, 30.1% and 33.3%, respectively. Aspirin, statins and angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers were used in 96.7%, 94.2% and 85.0% of cases, respectively. Beta blockers were used in 81.7% of cases. Average daily doses of most frequently used β blockers (metoprolol and bisoprolol) were 32% and 53% from target doses, respectively. In three cases β blockers were combined with ivabradin. Our results suggest that practitioners follow guidelines and consider CV prevention by treating CAD patients. Our data identified, however, unused potential for better control of increased HR by higher doses and combinations of HR-reducing agents.

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Control of Resting Heart Rate and Other Risk Factors Over a Three-year Period in Outpatients with Stable Coronary Artery Disease in Latvia

Proceedings of the Latvian Academy of Sciences Section B Natural Exact and Applied Sciences ◽

10.2478/prolas-2013-0081 ◽

2014 ◽

Vol 67 (6) ◽

pp. 457-465

Author(s):

Inga Balode ◽

Sanda Jēgere ◽

Iveta Bajāre ◽

Iveta Mintāle ◽

Inga Narbute ◽

...

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Coronary Artery Disease ◽

Heart Rate ◽

Coronary Artery ◽

Stable Coronary Artery Disease ◽

Density Lipoprotein ◽

Resting Heart Rate ◽

Baseline Systolic Blood Pressure ◽

Artery Disease

Abstract The aim of the study was to evaluate control of heart rate (HR) and other risk factors (RF) over athree-year period in coronary artery disease (CAD) outpatients in Latvia. Patients (n = 120) were examined and questioned at baseline time and annually (four times in total). Increased resting HR (≥70 bpm) when measured by palpation was present in 35.8% of cases at baseline time, 35.6%, 29.8% and 35.1% of cases at Y1, Y2 and Y3, respectively; when measured by electrocardiography: in 33.6% (baseline), 36.8% (Y1), 26.7% (Y2), 33.7% (Y3) of cases. The proportion of patients with increased HR did not significantly change in Y1–Y3 vs baseline. Systolic blood pressure was lower in Y1 and Y3 vs baseline (P = 0.005 and P = 0.003, respectively). The proportion of patients with increased blood pressure (≥140/90 mmHg) was lower in Y1, Y2 and Y3 than at baseline (P = 0.018, P = 0.030 and P = 0.017, respectively). The proportion of patients with a decreased level of high density lipoprotein cholesterol (<1.2 mmol/l for women and <1.0 mmol/l fom men) was lower in Y1–Y3 compared to baseline (P < 0.001). A substantial (about one-third) and stable proportion of patients with increased HR≥70 bpm over the three-year period in the examined sample of treated CAD patients indicates that there is a need for better control of this RF.

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Risk Factors of Cardiac Troponin T Elevation in Patients with Stable Coronary Artery Disease After Elective Coronary Drug-Eluting Stent Implantation

Clinical Cardiology ◽

10.1002/clc.20973 ◽

2011 ◽

Vol 34 (12) ◽

pp. 768-773 ◽

Cited By ~ 3

Author(s):

Zhang-Wei Chen ◽

Ju-Ying Qian ◽

Jian-Ying Ma ◽

Lei Ge ◽

Jun-Bo Ge

Keyword(s):

Risk Factors ◽

Coronary Artery Disease ◽

Coronary Artery ◽

Cardiac Troponin ◽

Troponin T ◽

Stable Coronary Artery Disease ◽

Drug Eluting Stent ◽

Cardiac Troponin T ◽

Drug Eluting ◽

Artery Disease

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Limited utilities of N-terminal pro B-type natriuretic peptide and other newer risk markers compared with traditional risk factors for prediction of significant angiographic lesions in stable coronary artery disease

Heart ◽

10.1136/hrt.2008.145425 ◽

2008 ◽

Vol 95 (4) ◽

pp. 297-303 ◽

Cited By ~ 17

Author(s):

A Peer ◽

G Falkensammer ◽

H Alber ◽

A Kroiss ◽

A Griesmacher ◽

...

Keyword(s):

Risk Factors ◽

Coronary Artery Disease ◽

Coronary Artery ◽

Natriuretic Peptide ◽

Stable Coronary Artery Disease ◽

Risk Markers ◽

Traditional Risk Factors ◽

Artery Disease

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Heart rate turbulence in patients with stable coronary artery disease and its relationship with the severity of the disease

Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology ◽

10.5543/tkda.2015.53496 ◽

2015 ◽

Author(s):

Onur Baydar

Keyword(s):

Coronary Artery Disease ◽

Heart Rate ◽

Coronary Artery ◽

Stable Coronary Artery Disease ◽

Heart Rate Turbulence ◽

Artery Disease ◽

Severity Of The Disease

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Simple heart rate and QT parameters during stress exercise testing to assess presence and severity of stable coronary artery disease

Future Cardiology ◽

10.2217/fca-2020-0163 ◽

2021 ◽

Author(s):

Murugaiyan Rajarajan ◽

Mugula Sudhakar Rao ◽

Padmakumar Ramachandran ◽

Ashwal A Jayaram

Keyword(s):

Coronary Artery Disease ◽

Heart Rate ◽

Coronary Artery ◽

Heart Rate Recovery ◽

Stable Coronary Artery Disease ◽

Peak Exercise ◽

P Value ◽

Characteristic Analysis ◽

Qt Variability ◽

Artery Disease

Aim: The relationship between QT prolongation and myocardial ischemia is well known, however not many studies have correlated corrected QT interval and heart rate recovery with the severity of coronary artery disease (CAD). Methods: This was a single-center, prospective, observational study which included 127 patients with CAD and 124 patients without CAD. Results: Corrected QT variability from peak to recovery correlated well with CAD with a p value of 0.03. Receiver operative characteristic analysis did not show any significant diagnostic accuracy with any heart rate or QT parameters for predicting the presence or severity of CAD. Conclusion: Coronary artery disease is predicted by reduced ability of the heart rate to rise from rest to peak exercise and reduced recovery of heart rate and corrected QT from peak exercise to recovery at 1 min.

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