Simple heart rate and QT parameters during stress exercise testing to assess presence and severity of stable coronary artery disease

2021 ◽  
Author(s):  
Murugaiyan Rajarajan ◽  
Mugula Sudhakar Rao ◽  
Padmakumar Ramachandran ◽  
Ashwal A Jayaram
Keyword(s):  
Coronary Artery Disease ◽  
Heart Rate ◽  
Coronary Artery ◽  
Heart Rate Recovery ◽  
Stable Coronary Artery Disease ◽  
Peak Exercise ◽  
P Value ◽  
Characteristic Analysis ◽  
Qt Variability ◽  
Artery Disease

Aim: The relationship between QT prolongation and myocardial ischemia is well known, however not many studies have correlated corrected QT interval and heart rate recovery with the severity of coronary artery disease (CAD). Methods: This was a single-center, prospective, observational study which included 127 patients with CAD and 124 patients without CAD. Results: Corrected QT variability from peak to recovery correlated well with CAD with a p value of 0.03. Receiver operative characteristic analysis did not show any significant diagnostic accuracy with any heart rate or QT parameters for predicting the presence or severity of CAD. Conclusion: Coronary artery disease is predicted by reduced ability of the heart rate to rise from rest to peak exercise and reduced recovery of heart rate and corrected QT from peak exercise to recovery at 1 min.

scholarly journals Decreased heart rate recovery may predict a high SYNTAX score in patients with stable coronary artery disease

2019 ◽  
Vol 19 (1) ◽  
pp. 109-115
Author(s):  
Sadık Volkan Emren ◽  
Rahman Bilal Gediz ◽  
Oktay Şenöz ◽  
Uğur Karagöz ◽  
Ersin Çağrı Şimşek ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Rate ◽  
Coronary Artery ◽  
Heart Rate Recovery ◽  
Stable Coronary Artery Disease ◽  
Recovery Period ◽  
Multivariate Logistic Regression Analysis ◽  
Syntax Score ◽  
Increased Risk ◽  
Artery Disease

An impaired heart rate recovery (HRR) has been associated with increased risk of cardiovascular events, cardiovascular, and all‐cause mortality. However, the diagnostic ability of HRR for the presence and severity of coronary artery disease (CAD) has not been clearly elucidated. Our aim was to investigate the relationship between HRR and the SYNTAX (SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery) score in patients with stable CAD (SCAD). A total of 406 patients with an abnormal treadmill exercise test and ≥50% coronary stenosis on coronary angiography were included. The HRR was calculated by subtracting the HR in the first minute of the recovery period from the maximum HR during exercise. The SYNTAX score ≥23 was accepted as high. Correlation of HRR with SYNTAX score and independent predictors of high SYNTAX score were determined. A high SYNTAX score was present in 172 (42%) patients. Mean HRR was lower in patients with a high SYNTAX score (9.8 ± 4.5 vs. 21.3 ± 9, p < 0.001). The SYNTAX score was negatively correlated with HRR (r: -0.580, p < 0.001). In multivariate logistic regression analysis, peripheral arterial disease (OR: 13.3; 95% CI: 3.120–34.520; p < 0.001), decreased HRR (OR: 0.780; 95% CI: 0.674–0.902; p = 0.001), peak systolic blood pressure (OR: 1.054; 95% CI: 1.023–1.087; p = 0.001), and peak HR (OR: 0.950; 95% CI: 0.923–0.977; p < 0.001) were found to be independent predictors of a high SYNTAX score. Our results showed that HRR is significantly correlated with the SYNTAX score, and a decreased HRR is an independent predictor of a high SYNTAX score in patients with SCAD.

scholarly journals Association between cardiac autonomic nervous dysfunction and the severity of coronary lesions in patients with stable coronary artery disease

2018 ◽  
Vol 46 (9) ◽  
pp. 3729-3740 ◽  
Author(s):  
Yafei Chen ◽  
Yijun Yu ◽  
Wusong Zou ◽  
Mingjing Zhang ◽  
Yuting Wang ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Rate ◽  
Coronary Artery ◽  
Heart Rate Recovery ◽  
Stable Coronary Artery Disease ◽  
Multivariate Logistic Regression Analysis ◽  
Control Group ◽  
Autonomic Nervous ◽  
Coronary Lesions ◽  
Artery Disease

Objective Autonomic dysfunction is recognized in patients with coronary artery disease (CAD) and is related to worse cardiovascular outcome. This study aimed to evaluate cardiac autonomic nervous function by heart rate recovery (HRR) and heart rate variability (HRV), and demonstrate their relationship with the severity of coronary lesions in patients with stable CAD (SCAD). Methods Consecutive patients without CAD (controls, n = 65) and those with SCAD (n = 63) were included in this study. Patients with SCAD were further divided into single- or two-/three-vessel disease, as well as <70% or ≥70% stenosis subgroups. The association between HRR/HRV and coronary lesions was analysed. Results HRR and HRV values were significantly lower in the SCAD group compared with the control group. Multivariate logistic regression analysis showed that abnormal HRR and HRV were risk factors of SCAD. Moreover, delayed HRR was a risk factor of the severity of coronary lesions. Conclusions Our results show that autonomic function is impaired in patients with SCAD and delayed HRR is closely related to the severity of coronary lesions.

scholarly journals The Relationship Between Heart Rate Recovery and Heart Rate Variability in Coronary Artery Disease

2006 ◽  
Vol 11 (2) ◽  
pp. 154-162 ◽  
Author(s):  
Harun Evrengul ◽  
Halil Tanriverdi ◽  
Sedat Kose ◽  
Basri Amasyali ◽  
Ayhan Kilic ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Coronary Artery ◽  
Heart Rate Recovery ◽  
Artery Disease ◽  
The Relationship

scholarly journals Determinants of heart rate turbulence in individuals without apparent heart disease and in patients with stable coronary artery disease

EP Europace ◽  
2015 ◽  
Vol 17 (12) ◽  
pp. 1855-1861 ◽  
Author(s):  
Gaetano Pinnacchio ◽  
Gaetano Antonio Lanza ◽  
Alessandra Stazi ◽  
Giulia Careri ◽  
Ilaria Coviello ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Rate ◽  
Heart Disease ◽  
Coronary Artery ◽  
Stable Coronary Artery Disease ◽  
Heart Rate Turbulence ◽  
Artery Disease

Effects of exercise training on heart rate recovery in coronary artery disease patients

2011 ◽  
Vol 163 (1-2) ◽  
pp. 121 ◽  
Author(s):  
V.R. Neves ◽  
A.M. Kiviniemi ◽  
A.J. Hautala ◽  
J. Karjalainen ◽  
A.M. Catai ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Heart Rate ◽  
Coronary Artery ◽  
Exercise Training ◽  
Heart Rate Recovery ◽  
Artery Disease
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