D2 receptor crosstalk with metabotropic glutamate receptors, but not with GABAB receptors, in the regulation of dopamine synthesis in rat brain

2016 ◽  
Vol 4 (Suppl. 2) ◽  
pp. A7.3
Author(s):  
Doaa Abass
Keyword(s):  
Rat Brain ◽  
Glutamate Receptors ◽  
Metabotropic Glutamate Receptors ◽  
D2 Receptor ◽  
Gabab Receptors ◽  
Dopamine Synthesis ◽  
Metabotropic Glutamate ◽  
Receptor Crosstalk

Expression of groups I and II metabotropic glutamate receptors in the rat brain during aging

2005 ◽  
Vol 1043 (1-2) ◽  
pp. 95-106 ◽  
Author(s):  
Agnes Simonyi ◽  
Richard T. Ngomba ◽  
Marianna Storto ◽  
Maria V. Catania ◽  
Laura A. Miller ◽  
...  
Keyword(s):  
Rat Brain ◽  
Glutamate Receptors ◽  
Metabotropic Glutamate Receptors ◽  
Metabotropic Glutamate

scholarly journals What is the role of neurotransmitter systems in cortical seizures?

2008 ◽  
pp. S111-S120
Author(s):  
P Mareš ◽  
H Kubová
Keyword(s):  
Glutamate Receptors ◽  
Metabotropic Glutamate Receptors ◽  
Gabab Receptor ◽  
Age Groups ◽  
Gabab Receptors ◽  
Neurotransmitter Systems ◽  
Metabotropic Glutamate ◽  
Rat Pups ◽  
Epileptic Afterdischarges

Epileptic afterdischarges (ADs) elicited by electrical stimulation of sensorimotor cortical area were used as a model to study the role of neurotransmitter systems in cortical seizures in three age groups of developing rats. Drugs augmenting inhibition mediated by GABAA receptors were found to suppress ADs in all age groups, their activity was usually more marked in younger than in 25-day-old rat pups. Drugs potentiating GABAB receptors exhibit lower efficacy and more complicated developmental profile than GABAA-ergic drugs. Effects of an antagonist of GABAB receptor--marked prolongation of ADs in all three age groups--suggest an important role of GABAB receptors in arrest of cortical seizures. Drugs affecting glutamate receptors exhibit variable effects, usually better expressed in older animals than in 12-day-old ones. No specific role for ionotropic as well as metabotropic glutamate receptors could be predicted. Activation of adenosinergic inhibitory modulatory system also exhibited anticonvulsant action in the present model. All three neurotransmitter systems probably participate in mechanisms of generation, maintenance and arrest of cortical seizures.

Distributions of the mRNAs for L-2-amino-4-phosphonobutyrate-sensitive metabotropic glutamate receptors, mGluR4 and mGluR7, in the rat brain

1995 ◽  
Vol 360 (4) ◽  
pp. 555-570 ◽  
Author(s):  
Hitoshi Ohishi ◽  
Chihiro Akazawa ◽  
Ryuichi Shigemoto ◽  
Shigetada Nakanishi ◽  
Noboru Mizuno
Keyword(s):  
Rat Brain ◽  
Glutamate Receptors ◽  
Metabotropic Glutamate Receptors ◽  
Metabotropic Glutamate

The depolarization-induced outflow of d-[3H]aspartate from rat brain slices is modulated by metabotropic glutamate receptors

1994 ◽  
Vol 24 (6) ◽  
pp. 525-532 ◽  
Author(s):  
Grazia Lombardi ◽  
Domenico E. Pellegrini-Giampietro ◽  
Patrizia Leonardi ◽  
Giovanna Cherici ◽  
Roberto Pellicciari ◽  
...  
Keyword(s):  
Rat Brain ◽  
Glutamate Receptors ◽  
Metabotropic Glutamate Receptors ◽  
Brain Slices ◽  
Metabotropic Glutamate

Expression cloning of GABAB receptors uncovers similarity to metabotropic glutamate receptors

Nature ◽  
1997 ◽  
Vol 386 (6622) ◽  
pp. 239-246 ◽  
Author(s):  
Klemens Kaupmann ◽  
Katharina Huggel ◽  
Jakob Heid ◽  
Peter J. Flor ◽  
Serge Bischoff ◽  
...  
Keyword(s):  
Glutamate Receptors ◽  
Metabotropic Glutamate Receptors ◽  
Gabab Receptors ◽  
Expression Cloning ◽  
Metabotropic Glutamate
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