THE SAFETY AND EFFICACY OF BLEOMYCIN, ETOPOSIDE AND CISPLATIN (BEP) CHEMOTHERAPY IN PATIENTS WITH MALIGNANT OVARIAN GERM CELL TUMOR

Author(s):  
Park Jeong-Yeol
2009 ◽  
Vol 2009 ◽  
pp. 1-3
Author(s):  
Ali Fuat Atmaca ◽  
Serkan Altınova ◽  
Abdullah Erdem Canda ◽  
M. Fuat Ozcan ◽  
Suleyman Alıcı ◽  
...  

A huge retroperitoneal tumor with a right orbital mass was detected and proved to be an extragonadal nonseminomatous germ cell tumor on biopsy. BEP chemotherapy caused some regression in orbital mass however no change in retroperitoneal tumor size as well as serum tumor marker levels occurred. Herein, we present a rarely seen entity of extragonadal retroperitoneal nonseminomatous germ cell tumor with synchronous orbital metastases and discuss its diagnosis and management.


2021 ◽  
Vol 57 (4) ◽  
pp. 351
Author(s):  
Agustinus Rizki ◽  
Laksmi Wulandari

Highlight:A 28-year-old male suffered chylothorax and mediastinal seminoma.The patient received bleomycin, etoposide and cisplatin chemotherapy for the management of mediastinal seminomas but he died beforeundergoing 5th cycle chemotherapy. Abstract:Seminoma is a type of germ cell tumor. In this case presentation, a rare primary germ cell tumor was reported in the form of mediastinal seminoma. A 28-year-old man with symptoms of shortness of breath, chest pain, swelling in the right upper extremity, enlarged lymph nodes in the colli region. Thoracic physical examination revealed signs of pleural fluid in the right hemithorax. After obtaining the results of radiological and pathological investigations, a mediastinal mass was obtained, then BEP chemotherapy was given. After 3 cycles of chemotherapy, a partial response was obtained. Patients with mediastinal seminoma treated with BEP base chemotherapy gave a partial response.


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