scholarly journals 11 / MATRIX METALLOPROTEINASE-1 (MMP-1) LEVELS AS A PREDICTIVE MARKER OF ORAL MUCOSITIS SEVERITY AMONG HEAD AND NECK CARCINOMA PATIENTS UNDERGOING RADIOTHERAPY

2018 ◽  
Author(s):  
Jerickson Abbie Flores
Keyword(s):  
Matrix Metalloproteinase ◽  
Head And Neck ◽  
Oral Mucositis ◽  
Predictive Marker ◽  
Head And Neck Carcinoma ◽  
Matrix Metalloproteinase 1 ◽  
Neck Carcinoma

scholarly journals Oral mucositis in patients undergoing radiation treatment for head and neck carcinoma

Cancer ◽  
2006 ◽  
Vol 106 (2) ◽  
pp. 329-336 ◽  
Author(s):  
Montserrat Vera-Llonch ◽  
Gerry Oster ◽  
May Hagiwara ◽  
Stephen Sonis
Keyword(s):  
Head And Neck ◽  
Oral Mucositis ◽  
Radiation Treatment ◽  
Head And Neck Carcinoma ◽  
Neck Carcinoma

scholarly journals Increased expression of membrane type 1-matrix metalloproteinase in head and neck carcinoma

Cancer ◽  
1997 ◽  
Vol 79 (1) ◽  
pp. 139-144 ◽  
Author(s):  
Tomokazu Yoshizaki ◽  
Hiroshi Sato ◽  
Yumiko Maruyama ◽  
Shigeyuki Murono ◽  
Mitsuru Furukawa ◽  
...  
Keyword(s):  
Matrix Metalloproteinase ◽  
Head And Neck ◽  
Head And Neck Carcinoma ◽  
Neck Carcinoma ◽  
Membrane Type

scholarly journals Combined TP53 mutation/3p loss correlates with decreased radiosensitivity and increased matrix-metalloproteinase activity in head and neck carcinoma

Oral Oncology ◽  
2015 ◽  
Vol 51 (5) ◽  
pp. 470-475 ◽  
Author(s):  
Sharat C. Raju ◽  
Samantha J. Hauff ◽  
Aaron J. Lemieux ◽  
Ryan K. Orosco ◽  
Andrew M. Gross ◽  
...  
Keyword(s):  
Matrix Metalloproteinase ◽  
Head And Neck ◽  
Tp53 Mutation ◽  
Head And Neck Carcinoma ◽  
Neck Carcinoma ◽  
Metalloproteinase Activity

Radiobiological modeling of radiation-induced acute mucosal toxicity (oral mucositis and pharyngeal mucositis): A single-institutional study of head-and-neck carcinoma

2021 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
ArunSingh Oinam ◽  
Balbir Singh ◽  
Gaganpreet Singh ◽  
Vivek Kumar ◽  
Rajesh Vashistha ◽  
...  
Keyword(s):  
Head And Neck ◽  
Oral Mucositis ◽  
Head And Neck Carcinoma ◽  
Neck Carcinoma ◽  
Radiation Induced

scholarly journals Is There an Interplay between Oral Microbiome, Head and Neck Carcinoma and Radiation-Induced Oral Mucositis?

Cancers ◽  
2021 ◽  
Vol 13 (23) ◽  
pp. 5902
Author(s):  
Patryk Gugnacki ◽  
Ewa Sierko
Keyword(s):  
Head And Neck ◽  
Oral Mucositis ◽  
Head And Neck Carcinoma ◽  
Radiation Reaction ◽  
Acute Radiation ◽  
Oral Microbiome ◽  
Positive Effects ◽  
Neck Carcinoma ◽  
Radiation Induced ◽  
The Impact

Head and neck carcinoma is one of the most common human malignancy types and it ranks as the sixth most common cancer worldwide. Nowadays, a great potential of microbiome research is observed in oncology—investigating the effect of oral microbiome in oncogenesis, occurrence of treatment side effects and response to anticancer therapies. The microbiome is a unique collection of microorganisms and their genetic material, interactions and products residing within the mucous membranes. The aim of this paper is to summarize current research on the oral microbiome and its impact on the development of head and neck cancer and radiation-induced oral mucositis. Human microbiome might determine an oncogenic effect by, among other things, inducing chronic inflammatory response, instigating cellular antiapoptotic signals, modulation of anticancer immunity or influencing xenobiotic metabolism. Influence of oral microbiome on radiation-induced oral mucositis is expressed by the production of additional inflammatory cytokines and facilitates progression and aggravation of mucositis. Exacerbated acute radiation reaction and bacterial superinfections lead to the deterioration of the patient’s condition and worsening of the quality of life. Simultaneously, positive effects of probiotics on the course of radiation-induced oral mucositis have been observed. Understanding the impact on the emerging acute radiation reaction on the composition of the microflora can be helpful in developing a multifactorial model to forecast the course of radiation-induced oral mucositis. Investigating these processes will allow us to create optimized and personalized preventive measures and treatment aimed at their formation mechanism. Further studies are needed to better establish the structure of the oral microbiome as well as the dynamics of its changes before and after therapy. It will help to expand the understanding of the biological function of commensal and pathogenic oral microbiota in HNC carcinogenesis and the development of radiation-induced oral mucositis.

The Role Of Peptide Growth Factors In Head And Neck Carcinoma

1992 ◽  
Vol 25 (5) ◽  
pp. 1105-1115 ◽  
Author(s):  
Jennifer R. Grandis ◽  
David J. Tweardy
Keyword(s):  
Growth Factors ◽  
Head And Neck ◽  
Head And Neck Carcinoma ◽  
Peptide Growth Factors ◽  
Neck Carcinoma

Experimental Model of Highly Invasive Phenotypes from Cultured Head and Neck Carcinoma and its Biological Characteristics

2019 ◽  
Vol 70 (2) ◽  
pp. 179-180
Author(s):  
H. Kanaya ◽  
K. Goto ◽  
H. Hirabayashi ◽  
S. Haruna
Keyword(s):  
Head And Neck ◽  
Experimental Model ◽  
Head And Neck Carcinoma ◽  
Biological Characteristics ◽  
Neck Carcinoma

Diagnostic and Therapeutic Strategy for Multiple Primary Cancers in Patients with Head and Neck Carcinoma

2014 ◽  
Vol 65 (2) ◽  
pp. 115-115
Author(s):  
T. Yamashita ◽  
K. Araki ◽  
M. Tomifuji ◽  
A. Shiotani
Keyword(s):  
Head And Neck ◽  
Therapeutic Strategy ◽  
Head And Neck Carcinoma ◽  
Multiple Primary Cancers ◽  
Neck Carcinoma ◽  
Multiple Primary
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