Evaluation of the Severity of Mitral Valvular Regurgitation with Doppler Echo-Cardiography Using Proximal Flow Convergence Method

2009 ◽  
Vol 4 (3) ◽  
pp. 1-12
Author(s):  
Pinjari Abdul Khayum ◽  
◽  
M.N. Giriprasad ◽  
P.V. Sridevi ◽  
◽  
...  
Keyword(s):  
Valvular Regurgitation ◽  
Convergence Method ◽  
Flow Convergence

scholarly journals Application of the proximal flow convergence method to calculate the effective regurgitant orifice area in aortic regurgitation

1998 ◽  
Vol 32 (4) ◽  
pp. 1032-1039 ◽  
Author(s):  
Christophe M Tribouilloy ◽  
Maurice Enriquez-Sarano ◽  
Sara L Fett ◽  
Kent R Bailey ◽  
James B Seward ◽  
...  
Keyword(s):  
Aortic Regurgitation ◽  
Orifice Area ◽  
Convergence Method ◽  
Flow Convergence ◽  
Regurgitant Orifice Area

Global regurgitant volume: approaching the critical mass in valvular-driven heart failure

2019 ◽  
Author(s):  
Philipp E Bartko ◽  
Henrike Arfsten ◽  
Gregor Heitzinger ◽  
Noemi Pavo ◽  
Georg Spinka ◽  
...  
Keyword(s):  
Heart Failure ◽  
Critical Mass ◽  
Regurgitant Volume ◽  
Reduced Ejection Fraction ◽  
Patients With Heart Failure ◽  
Convergence Method ◽  
Flow Convergence ◽  
Increasing Risk

Abstract Aims Recent progress in the diagnosis of functional valve regurgitation forms a coherent perception of severity thresholds by quantitative assessment. However, thresholds focused on either valve in isolation—not accounting for the global haemodynamic burden arising from concomitant functional regurgitation of the mitral and tricuspid valves. We sought to determine whether the global regurgitant volume is associated with adverse cardiac remodelling and mortality. Methods and results This long-term observational study included 414 patients on guideline-directed medical therapy. Baseline global regurgitant load defined as the sum of mitral and tricuspid regurgitant volume was assessed by the proximal flow convergence method. All-cause mortality during 5 years follow-up served as the primary endpoint. The median global regurgitant load was 30 mL (interquartile range 15–49) with 67% accounting for mitral and 33% accounting for tricuspid regurgitant volume. The global regurgitant load had significant impact on outcome with a crude hazard ratio of 1.46 (1.28–1.66; P < 0.001) for a 1-SD increase in global regurgitant volume, results that remained virtually unchanged after bootstrap or clinical confounder-based adjustment (P < 0.001 for adjusted models). Spline curve analysis showed a linearly increasing risk with a threshold of 50 mL and sustained increasing risk thereafter. Conclusions The present study demonstrates the detrimental effect of the global regurgitant load in patients with heart failure with reduced ejection fraction. The threshold where heart failure is driven by the valve lesions is a global regurgitant volume of 50 mL with continuously increasing risk beyond that threshold. Future studies need to address whether an attempt to reduce the global regurgitant volume can improve outcome.

scholarly journals P1580 Global regurgitant volume - approaching the critical mass in valvular-driven heart failure

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
G Spinka ◽  
P Bartko ◽  
H Arfsten ◽  
G Heitzinger ◽  
N Pavo ◽  
...  
Keyword(s):  
Heart Failure ◽  
Critical Mass ◽  
Regurgitant Volume ◽  
All Cause Mortality ◽  
Convergence Method ◽  
Flow Convergence ◽  
Increasing Risk ◽  
Valve Lesions

Abstract Aims Recent progress in the diagnosis of functional valve regurgitation forms a coherent perception of severity thresholds by quantitative assessment. However, thresholds focused on either valve in isolation -not accounting for the global hemodynamic burden arising from concomitant functional regurgitation of the mitral and tricuspid valves. We sought to determine whether the global regurgitant volume is associated with adverse cardiac remodeling and mortality. Methods and results This long-term observational study included 414 patients on guideline-directed medical therapy. Baseline global regurgitant load defined as the sum of mitral and tricuspid regurgitant volume was assessed by the proximal flow convergence method. All-cause mortality during five years follow-up served as the primary endpoint. The median global regurgitant load was 30ml (IQR 15-49) with 67% accounting for mitral and 33% accounting for tricuspid regurgitant volume. The global regurgitant load had significant impact on outcome with a crude HR of 1.46 (1.28-1.66; P &lt; 0.001) for a 1-SD increase in global regurgitant volume, results that remained virtually unchanged after bootstrap or clinical confounder-based adjustment (P &lt; 0.001 for adjusted models). Spline curve analysis showed a linearly increasing risk with a threshold of 50ml and sustained increasing risk thereafter. Conclusions The present study demonstrates the detrimental effect of the global regurgitant load in patients with HFrEF. The threshold where heart failure is driven by the valve lesions is a global regurgitant volume of 50ml with continuously increasing risk beyond that threshold. Future studies need to address whether an attempt to reduce the global regurgitant volume can improve outcome. Abstract P1580 Figure 1 - Global RegVol

scholarly journals Validation of the proximal flow convergence method. Calculation of orifice area in patients with mitral stenosis.

Circulation ◽  
1993 ◽  
Vol 88 (3) ◽  
pp. 1157-1165 ◽  
Author(s):  
L Rodriguez ◽  
J D Thomas ◽  
V Monterroso ◽  
A E Weyman ◽  
P Harrigan ◽  
...  
Keyword(s):  
Mitral Stenosis ◽  
Orifice Area ◽  
Method Calculation ◽  
Convergence Method ◽  
Flow Convergence

scholarly journals IMPACT OF THE ETIOLOGY OF MITRAL REGURGITATION ON CALCULATION OF REGURGITANT VOLUME USING THE PROXIMAL FLOW CONVERGENCE METHOD

2013 ◽  
Vol 61 (10) ◽  
pp. E882
Author(s):  
Byung Joo Sun ◽  
Jeong Yoon Jang ◽  
Seungmo Kang ◽  
Yun-Sil Choi ◽  
Min Kyoung Jang ◽  
...  
Keyword(s):  
Mitral Regurgitation ◽  
Regurgitant Volume ◽  
Convergence Method ◽  
Flow Convergence
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